{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Giant+Lymph+Node",
    "query": {
      "condition": "Giant Lymph Node"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T08:03:21.634Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02871050",
      "title": "Castleman Disease Collaborative Network Biobank",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Castleman Disease",
        "Castleman's Disease",
        "Giant Lymph Node Hyperplasia",
        "Angiofollicular Lymph Hyperplasia",
        "Angiofollicular Lymph Node Hyperplasia",
        "Angiofollicular Lymphoid Hyperplasia",
        "GLNH",
        "Hyperplasia",
        "Giant Lymph Node"
      ],
      "interventions": [
        {
          "name": "Sample Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Castleman Disease Collaborative Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2016-06",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2018-07-31",
      "last_synced_at": "2026-07-22T08:03:21.634Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02871050"
    },
    {
      "nct_id": "NCT02853968",
      "title": "Unlock the Cell: Castleman's Disease Flow Cytometry Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Castleman Disease",
        "Angiofollicular Lymphoid Hyperplasia",
        "GLNH",
        "Hyperplasia",
        "Castleman's Disease",
        "Angiofollicular Lymph Hyperplasia",
        "Giant Lymph Node Hyperplasia"
      ],
      "interventions": [
        {
          "name": "Blood draw/buccal swab",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 130,
      "start_date": "2016-02",
      "completion_date": "2019-03-30",
      "has_results": false,
      "last_update_posted_date": "2020-03-26",
      "last_synced_at": "2026-07-22T08:03:21.634Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02853968"
    },
    {
      "nct_id": "NCT02817997",
      "title": "International Registry for Patients With Castleman Disease",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Castleman Disease",
        "Castleman's Disease",
        "Giant Lymph Node Hyperplasia",
        "Angiofollicular Lymph Hyperplasia",
        "Angiofollicular Lymph Node Hyperplasia",
        "Angiofollicular Lymphoid Hyperplasia",
        "GLNH",
        "Hyperplasia, Giant Lymph Node",
        "Lymph Node Hyperplasia, Giant"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2016-10",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-03-03",
      "last_synced_at": "2026-07-22T08:03:21.634Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02817997"
    },
    {
      "nct_id": "NCT02176070",
      "title": "Reproductive Health in Men and Women With Vasculitis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Giant Cell Arteritis",
        "Takayasu's Arteritis",
        "Polyarteritis Nodosa",
        "Wegener's Granulomatosis",
        "Microscopic Polyangiitis",
        "Churg-Strauss Syndrome",
        "Behcet's Disease",
        "Kawasaki Disease",
        "Henoch-schoenlein Purpura",
        "Vasculitis, Central Nervous System",
        "Drug-induced Necrotizing Vasculitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 467,
      "start_date": "2011-02",
      "completion_date": "2012-03",
      "has_results": false,
      "last_update_posted_date": "2014-06-26",
      "last_synced_at": "2026-07-22T08:03:21.634Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02176070"
    },
    {
      "nct_id": "NCT00412321",
      "title": "A Safety and Efficacy Study of CNTO 328 in Patients With B-Cell Non-Hodgkin's Lymphoma, Multiple Myeloma, or Castleman's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Lymphoma, Non-Hodgkin",
        "Multiple Myeloma",
        "Giant Lymph Node Hyperplasia"
      ],
      "interventions": [
        {
          "name": "CNTO 328",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Centocor, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2005-05",
      "completion_date": "2011-04",
      "has_results": false,
      "last_update_posted_date": "2014-07-01",
      "last_synced_at": "2026-07-22T08:03:21.634Z",
      "location_count": 9,
      "location_summary": "Little Rock, Arkansas • Tampa, Florida • Atlanta, Georgia + 6 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Box 302",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00412321"
    },
    {
      "nct_id": "NCT01441063",
      "title": "Tocilizumab for KSHV-Associated Multicentric Castleman Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Castleman Disease",
        "Multicentric Castleman Disease",
        "Giant Lymph Node Hyperplasia"
      ],
      "interventions": [
        {
          "name": "Zidovudine",
          "type": "DRUG"
        },
        {
          "name": "Tocilizumab",
          "type": "DRUG"
        },
        {
          "name": "Valganciclovir (VGC)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2011-09-13",
      "completion_date": "2020-10-05",
      "has_results": true,
      "last_update_posted_date": "2020-10-27",
      "last_synced_at": "2026-07-22T08:03:21.634Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01441063"
    }
  ]
}