{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gingival+Diseases&page=4",
    "query": {
      "condition": "Gingival Diseases",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 253,
    "total_pages": 26,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gingival+Diseases&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gingival+Diseases&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T18:45:24.862Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07500935",
      "title": "Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus",
        "Gingival Recession, Generalized",
        "Gingival Recession, Localized"
      ],
      "interventions": [
        {
          "name": "Free gingival graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mauro Santamaria",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-09-09",
      "completion_date": "2030-04",
      "has_results": false,
      "last_update_posted_date": "2026-10-22",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07500935"
    },
    {
      "nct_id": "NCT00679081",
      "title": "A Pilot Study of CelTx(TM) (Apligraf®) in the Treatment of Gingival Recession Requiring Root Coverage",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Gingival Recession"
      ],
      "interventions": [
        {
          "name": "CelTx",
          "type": "DEVICE"
        },
        {
          "name": "Autologous sub-epithelial connective tissue graft",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Organogenesis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 15,
      "start_date": "2008-05",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2012-01-11",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00679081"
    },
    {
      "nct_id": "NCT05961566",
      "title": "Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Recession, Gingival"
      ],
      "interventions": [
        {
          "name": "Use of collagen matrix after subepithelial connective tissue graft harvest",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hailey Bivens",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-10-01",
      "completion_date": "2025-03-30",
      "has_results": false,
      "last_update_posted_date": "2024-01-19",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05961566"
    },
    {
      "nct_id": "NCT01877421",
      "title": "Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "2 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "4 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "6 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "10 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "20 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "30 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "50 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "75 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "100 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "U.S. Army Medical Research and Development Command",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 135,
      "start_date": "2014-02-25",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2020-02-13",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01877421"
    },
    {
      "nct_id": "NCT02709785",
      "title": "SmartMouth Advanced Clinical Formula Clinical Research Design Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "SmartMouth Clinical DDS mouthrinse",
          "type": "DRUG"
        },
        {
          "name": "0.12% chlorhexidine rinse",
          "type": "DRUG"
        },
        {
          "name": "Placebo rinse",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 80,
      "start_date": "2016-03",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2018-12-04",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 2,
      "location_summary": "Alton, Illinois • St Louis, Missouri",
      "locations": [
        {
          "city": "Alton",
          "state": "Illinois"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02709785"
    },
    {
      "nct_id": "NCT05633511",
      "title": "Changes of Soft Tissue Grafting: A Randomized Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Recession"
      ],
      "interventions": [
        {
          "name": "Split Mouth Design",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2023-01-11",
      "completion_date": "2036-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05633511"
    },
    {
      "nct_id": "NCT06933368",
      "title": "A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Crest Cavity Protection Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Experimental Mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 138,
      "start_date": "2025-04-21",
      "completion_date": "2025-08-14",
      "has_results": true,
      "last_update_posted_date": "2026-10-26",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06933368"
    },
    {
      "nct_id": "NCT00871676",
      "title": "Use of Chewing Gum to Facilitate Appetite Control and Weight Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Lifestyle modification",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lifestyle modification plus gum",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 146,
      "start_date": "2006-05",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2016-08-17",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00871676"
    },
    {
      "nct_id": "NCT01559662",
      "title": "Effect of Sugared Chewing Gum on Gastrointestinal Recovery After Major Colorectal Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Ileus"
      ],
      "interventions": [
        {
          "name": "Sugared Chewing Gum (Juicy Fruit)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 114,
      "start_date": "2010-08",
      "completion_date": "2012-03",
      "has_results": false,
      "last_update_posted_date": "2012-08-15",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01559662"
    },
    {
      "nct_id": "NCT02027597",
      "title": "Improving Oral Health With Serious Games",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caries",
        "Tooth Decay",
        "Cavities",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Attack of the S. Mutans",
          "type": "OTHER"
        },
        {
          "name": "Follow-up",
          "type": "OTHER"
        },
        {
          "name": "SnowWorld",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "8 Years to 12 Years"
      },
      "enrollment_count": 161,
      "start_date": "2008-10",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2014-01-06",
      "last_synced_at": "2026-11-15T18:45:24.862Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02027597"
    }
  ]
}