{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Glabellar+Lines&page=2",
    "query": {
      "condition": "Glabellar Lines",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Glabellar+Lines&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T12:40:41.630Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02184988",
      "title": "Safety Study of DWP-450 (Botulinum Purified Neurotoxin, Type A) Injection to Treat Glabellar Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Glabellar Frown Lines"
      ],
      "interventions": [
        {
          "name": "Botulinum purified neurotoxin, Type A",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Evolus, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 352,
      "start_date": "2014-08",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2019-04-24",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02184988"
    },
    {
      "nct_id": "NCT02176356",
      "title": "Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Facial Rhytides",
        "Crow's Feet Lines",
        "Glabellar Lines",
        "Nasolabial Fold"
      ],
      "interventions": [
        {
          "name": "onabotulinumtoxinA",
          "type": "BIOLOGICAL"
        },
        {
          "name": "bimatoprost ophthalmic solution 0.03%",
          "type": "DRUG"
        },
        {
          "name": "JUVÉDERM® ULTRA XC",
          "type": "DEVICE"
        },
        {
          "name": "JUVÉDERM® ULTRA PLUS XC",
          "type": "DEVICE"
        },
        {
          "name": "JUVÉDERM® VOLUMA® XC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "35 Years to 65 Years"
      },
      "enrollment_count": 116,
      "start_date": "2014-06-30",
      "completion_date": "2015-05-03",
      "has_results": true,
      "last_update_posted_date": "2019-01-09",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02176356"
    },
    {
      "nct_id": "NCT01801826",
      "title": "A Prospective Study Evaluating the Treatment of Forehead and/or Glabellar Lines With the Cryo-Touch IV Device",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Frown Lines",
        "Glabellar Frown Lines"
      ],
      "interventions": [
        {
          "name": "Treatment with CryoTouch IV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Pacira Pharmaceuticals, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 61,
      "start_date": "2013-01",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2015-03-24",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 2,
      "location_summary": "Beverly Hills, California • San Francisco, California",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01801826"
    },
    {
      "nct_id": "NCT00856414",
      "title": "Patient Satisfaction With Treatment of BOTOX® Cosmetic for the Temporary Correction of Moderate to Severe Glabellar Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Skin Aging"
      ],
      "interventions": [
        {
          "name": "botulinum toxin Type A",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 55 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2009-03",
      "completion_date": "2009-04",
      "has_results": true,
      "last_update_posted_date": "2019-01-29",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 2,
      "location_summary": "West Palm Beach, Florida • Livonia, Michigan",
      "locations": [
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Livonia",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00856414"
    },
    {
      "nct_id": "NCT06161246",
      "title": "A Controlled Study on Pain Management With Injection of Botulinum Toxin for Glabellar Line Correction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Injection Site Discomfort"
      ],
      "interventions": [
        {
          "name": "Vibrating Beauty Bar",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-10-23",
      "completion_date": "2024-02-15",
      "has_results": false,
      "last_update_posted_date": "2024-03-22",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06161246"
    },
    {
      "nct_id": "NCT05013424",
      "title": "A Study of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Glabellar Lines"
      ],
      "interventions": [
        {
          "name": "Formulation A: OnabotulinumtoxinA",
          "type": "DRUG"
        },
        {
          "name": "Formulation B: OnabotulinumtoxinA",
          "type": "DRUG"
        },
        {
          "name": "Formulation C: OnabotulinumtoxinA",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 92,
      "start_date": "2021-09-01",
      "completion_date": "2022-07-07",
      "has_results": true,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 5,
      "location_summary": "Glendale, Arizona • Coral Gables, Florida • New Orleans, Louisiana + 2 more",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Mount Kisco",
          "state": "New York"
        },
        {
          "city": "Pflugerville",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05013424"
    },
    {
      "nct_id": "NCT04715048",
      "title": "Split-Face Study Comparing Botox and Jeuveau in Treating Glabellar Lines",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Glabellar Frown Lines"
      ],
      "interventions": [
        {
          "name": "PrabotulinumtoxinA",
          "type": "DRUG"
        },
        {
          "name": "Onabotulinum toxin A",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2021-01-01",
      "completion_date": "2025-06",
      "has_results": false,
      "last_update_posted_date": "2023-12-14",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04715048"
    },
    {
      "nct_id": "NCT05248880",
      "title": "A Study to Assess Adverse Events and Change in Disease Activity of Intramuscular AGN-151586 Injection in Toxin-Naïve Adult Participants With Glabellar Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Glabellar Lines"
      ],
      "interventions": [
        {
          "name": "AGN-151586",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AbbVie",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 309,
      "start_date": "2022-03-08",
      "completion_date": "2023-02-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 12,
      "location_summary": "Scottsdale, Arizona • Newport Beach, California • Redondo Beach, California + 9 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Redondo Beach",
          "state": "California"
        },
        {
          "city": "Westport",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05248880"
    },
    {
      "nct_id": "NCT03687736",
      "title": "Subject Satisfaction With AbobutulinumtoxinA Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Glabellar Frown Lines"
      ],
      "interventions": [
        {
          "name": "AbobotulinumtoxinA",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 120,
      "start_date": "2018-10-02",
      "completion_date": "2019-12-04",
      "has_results": true,
      "last_update_posted_date": "2022-08-26",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 6,
      "location_summary": "Los Angeles, California • San Francisco, California • Santa Monica, California + 3 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03687736"
    },
    {
      "nct_id": "NCT02718118",
      "title": "Comparison of Dysport Reconstitution at 1.5 mL and 2.5 mL for the Treatment of Moderate to Severe Glabellar Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Glabellar Lines",
        "Wrinkles"
      ],
      "interventions": [
        {
          "name": "Dysport reconstituted at 1.5 mL (0.05 mL/injection)",
          "type": "DEVICE"
        },
        {
          "name": "Dysport reconstituted at 2.5 mL (0.08 mL/injection)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 60,
      "start_date": "2016-04",
      "completion_date": "2016-10",
      "has_results": true,
      "last_update_posted_date": "2022-08-01",
      "last_synced_at": "2026-06-11T12:40:41.630Z",
      "location_count": 3,
      "location_summary": "Greenwood Village, Colorado • Coral Gables, Florida • Smithtown, New York",
      "locations": [
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Smithtown",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02718118"
    }
  ]
}