{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Glaucoma+Eye&page=2", "query": { "condition": "Glaucoma Eye", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Glaucoma+Eye&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T05:12:12.319Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03691649", "title": "A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Glaucoma and Ocular Hypertension" ], "interventions": [ { "name": "DE-117 Ophthalmic Solution", "type": "DRUG" }, { "name": "Timolol Maleate Ophthalmic Solution 0.5%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Months", "maximum_age": null, "sex": "ALL", "summary": "12 Months and older" }, "enrollment_count": 426, "start_date": "2018-09-14", "completion_date": "2020-09-03", "has_results": true, "last_update_posted_date": "2023-08-30", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 47, "location_summary": "Phoenix, Arizona • Sun City, Arizona • Burbank, California + 40 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Burbank", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Mission Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03691649" }, { "nct_id": "NCT00846989", "title": "Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "RKI983A", "type": "DRUG" }, { "name": "Latanoprost", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 276, "start_date": "2009-01", "completion_date": "2009-04", "has_results": false, "last_update_posted_date": "2020-12-19", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 29, "location_summary": "Artesia, California • Inglewood, California • La Jolla, California + 25 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Inglewood", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Poway", "state": "California" }, { "city": "Stockton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00846989" }, { "nct_id": "NCT02083289", "title": "A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ocular Hypertension", "Open Angle-glaucoma" ], "interventions": [ { "name": "ONO-9054", "type": "DRUG" }, { "name": "Latanoprost", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ono Pharmaceutical Co., Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 123, "start_date": "2014-05", "completion_date": null, "has_results": false, "last_update_posted_date": "2016-02-25", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 12, "location_summary": "Los Angeles, California • Mission Hills, California • Newport Beach, California + 9 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Mission Hills", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Petaluma", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02083289" }, { "nct_id": "NCT04676126", "title": "Augmented Macular Pigment-containing Nutraceutical and Central Visual Function", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Glaucoma", "Glaucoma Eye", "Glaucoma, Open-Angle" ], "interventions": [ { "name": "Lumega-Z", "type": "DIETARY_SUPPLEMENT" }, { "name": "Dorzolamide Hcl 2% Oph Soln", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG", "OTHER" ], "sponsor": "University of the Incarnate Word", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2021-05", "completion_date": "2022-05", "has_results": false, "last_update_posted_date": "2022-10-04", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04676126" }, { "nct_id": "NCT02674854", "title": "Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Open-angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "PG324 Ophthalmic Solution 0.02%/0.005%", "type": "DRUG" }, { "name": "Netarsudil (AR-13324) ophthalmic solution 0.02%", "type": "DRUG" }, { "name": "Latanoprost ophthalmic solution 0.005%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aerie Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 750, "start_date": "2016-02", "completion_date": "2017-03", "has_results": true, "last_update_posted_date": "2019-05-21", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 1, "location_summary": "Bedminster, New Jersey", "locations": [ { "city": "Bedminster", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT02674854" }, { "nct_id": "NCT00402493", "title": "Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "ibuprofen, latanoprost, brimonidine", "type": "DRUG" }, { "name": "Ibuprofen, brimonidine, latanoprost", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Philadelphia Eye Associates", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 51, "start_date": "2006-12", "completion_date": "2008-03", "has_results": false, "last_update_posted_date": "2018-04-04", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 3, "location_summary": "Willingboro, New Jersey • Philadelphia, Pennsylvania", "locations": [ { "city": "Willingboro", "state": "New Jersey" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00402493" }, { "nct_id": "NCT00338533", "title": "Endoscopic Goniotomy for Infantile Glaucoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "endoscopic goniotomy", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Week", "maximum_age": "3 Years", "sex": "ALL", "summary": "1 Week to 3 Years" }, "enrollment_count": 7, "start_date": "1997-04", "completion_date": "2007-07", "has_results": false, "last_update_posted_date": "2013-01-08", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00338533" }, { "nct_id": "NCT07218783", "title": "Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cataract", "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Bimatoprost Implant System", "type": "DRUG" }, { "name": "SpyGlass IOL", "type": "DEVICE" }, { "name": "Timolol Maleate Ophthalmic Solution, 0.5%", "type": "DRUG" }, { "name": "Commercial IOL", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "SpyGlass Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 400, "start_date": "2025-10-15", "completion_date": "2031-03-31", "has_results": false, "last_update_posted_date": "2025-10-20", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07218783" }, { "nct_id": "NCT03216902", "title": "A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Open-angle Glaucoma, Ocular Hypertension" ], "interventions": [ { "name": "Vehicle of DE-126 Ophthalmic Solution, high dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical ultra-low dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical low dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical medium dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical high dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "0.005% Latanoprost Ophthalmic Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 241, "start_date": "2017-07-25", "completion_date": "2018-02-27", "has_results": true, "last_update_posted_date": "2020-10-23", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 12, "location_summary": "Artesia, California • Mission Hills, California • Newport Beach, California + 9 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Mission Hills", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Petaluma", "state": "California" }, { "city": "Largo", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03216902" }, { "nct_id": "NCT03057496", "title": "Collision Warning Device for Blind and Visually Impaired", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hemianopia", "Hemianopsia", "Peripheral Visual Field Defect", "Blindness", "Retinitis Pigmentosa", "Glaucoma" ], "interventions": [ { "name": "Collision warning device", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Massachusetts Eye and Ear Infirmary", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 49, "start_date": "2018-01-22", "completion_date": "2019-12-05", "has_results": true, "last_update_posted_date": "2021-02-10", "last_synced_at": "2026-05-22T05:12:12.319Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03057496" } ] }