{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Glioblastoma+Multiforme%2FAnaplastic+Astrocytoma&page=3", "query": { "condition": "Glioblastoma Multiforme/Anaplastic Astrocytoma", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 343, "total_pages": 35, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Glioblastoma+Multiforme%2FAnaplastic+Astrocytoma&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Glioblastoma+Multiforme%2FAnaplastic+Astrocytoma&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-04T01:37:59.244Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04295759", "title": "INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Glioblastoma Multiforme", "Anaplastic Astrocytoma", "Anaplastic Oligodendroglioma", "DIPG", "High-grade Astrocytoma NOS", "CNS Primary Tumor, NOS (Malignant Glioma)" ], "interventions": [ { "name": "INCB7839", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pediatric Brain Tumor Consortium", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "3 Years to 21 Years" }, "enrollment_count": 13, "start_date": "2020-07-27", "completion_date": "2026-09-08", "has_results": true, "last_update_posted_date": "2026-10-01", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 11, "location_summary": "Los Angeles, California • Palo Alto, California • Aurora, Colorado + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04295759" }, { "nct_id": "NCT03911388", "title": "HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Neoplasms, Brain", "Glioblastoma Multiforme", "Glioblastoma of Cerebellum", "Neoplasms", "Astrocytoma", "Astrocytoma, Cerebellar", "Neuroectodermal Tumors", "Neuroectodermal Tumors, Primitive", "Cerebellar PNET, Childhood", "Cerebellar Neoplasms", "Cerebellar Neoplasms, Primary", "Cerebellar Neoplasm, Malignant", "Cerebellar Neoplasm Malignant Primary", "Neoplasm Metastases", "Neoplasm Malignant", "Neoplasms, Neuroepithelial", "Neoplasms, Germ Cell and Embryonal", "Neoplasms by Histologic Type", "Neoplasms, Glandular and Epithelial", "Neoplasms, Nerve Tissue", "Central Nervous System Neoplasms, Primary", "Central Nervous System Neoplasms, Malignant", "Nervous System Neoplasms", "Neoplasms by Site", "Brain Diseases", "Central Nervous System Diseases", "Nervous System Diseases", "Medulloblastoma Recurrent", "HSV", "Virus", "Pediatric Brain Tumor", "Nervous System Cancer", "Primitive Neuroectodermal Tumor (PNET) of Cerebellum" ], "interventions": [ { "name": "G207", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "36 Months", "maximum_age": "22 Years", "sex": "ALL", "summary": "36 Months to 22 Years" }, "enrollment_count": 24, "start_date": "2019-09-12", "completion_date": "2027-09-01", "has_results": false, "last_update_posted_date": "2026-09-04", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 3, "location_summary": "Birmingham, Alabama • St Louis, Missouri • Houston, Texas", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03911388" }, { "nct_id": "NCT00610571", "title": "Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Glioblastoma", "Gliosarcoma", "Anaplastic Astrocytoma" ], "interventions": [ { "name": "Oral Topotecan and Temodar", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Katy Peters", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 62, "start_date": "2004-04", "completion_date": "2012-04", "has_results": false, "last_update_posted_date": "2013-10-25", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00610571" }, { "nct_id": "NCT03919071", "title": "Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Anaplastic Astrocytoma", "Anaplastic Astrocytoma, Not Otherwise Specified", "Anaplastic Ganglioglioma", "Anaplastic Pleomorphic Xanthoastrocytoma", "Glioblastoma", "Malignant Glioma", "WHO Grade 3 Glioma", "WHO Grade 4 Glioma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Dabrafenib Mesylate", "type": "DRUG" }, { "name": "Lumbar Puncture", "type": "PROCEDURE" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Radiation Therapy", "type": "RADIATION" }, { "name": "Trametinib Dimethyl Sulfoxide", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG", "RADIATION" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "3 Years to 25 Years" }, "enrollment_count": 58, "start_date": "2020-02-20", "completion_date": "2027-09-30", "has_results": false, "last_update_posted_date": "2026-07-10", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 130, "location_summary": "Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 106 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Downey", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03919071" }, { "nct_id": "NCT01884740", "title": "Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Glioblastoma Multiforme", "Fibrillary Astrocytoma of Brain", "Glioma of Brainstem", "Anaplastic Astrocytoma", "Pilomyxoid Astrocytoma", "Mixed Oligodendroglioma-Astrocytoma", "Brain Stem Glioma", "Diffuse Intrinsic Pontine Glioma" ], "interventions": [ { "name": "SIACI of Erbitux and Bevacizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "21 Years", "sex": "ALL", "summary": "1 Year to 21 Years" }, "enrollment_count": 13, "start_date": "2013-06", "completion_date": "2018-10", "has_results": true, "last_update_posted_date": "2022-08-09", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01884740" }, { "nct_id": "NCT02055196", "title": "Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adult Anaplastic Astrocytoma", "Adult Anaplastic Oligodendroglioma", "Adult Giant Cell Glioblastoma", "Adult Glioblastoma", "Adult Gliosarcoma", "Recurrent Adult Brain Tumor" ], "interventions": [ { "name": "carboxylesterase-expressing allogeneic neural stem cells", "type": "BIOLOGICAL" }, { "name": "irinotecan hydrochloride", "type": "DRUG" }, { "name": "laboratory biomarker analysis", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "OTHER" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 0, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2014-06-02", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 1, "location_summary": "Duarte, California", "locations": [ { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02055196" }, { "nct_id": "NCT00003348", "title": "Carmustine Plus O(6)-Benzylguanine in Treating Patients With Recurrent or Progressive Gliomas of the Brain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Brain and Central Nervous System Tumors" ], "interventions": [ { "name": "O6-benzylguanine", "type": "DRUG" }, { "name": "carmustine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 56, "start_date": "1998-05", "completion_date": "2000-08", "has_results": false, "last_update_posted_date": "2013-02-20", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00003348" }, { "nct_id": "NCT00268385", "title": "Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adult Anaplastic Astrocytoma", "Adult Anaplastic Oligodendroglioma", "Adult Giant Cell Glioblastoma", "Adult Glioblastoma", "Adult Gliosarcoma", "Adult Mixed Glioma", "Recurrent Adult Brain Neoplasm" ], "interventions": [ { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Pharmacological Study", "type": "OTHER" }, { "name": "Temozolomide", "type": "DRUG" }, { "name": "Vorinostat", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2005-12-16", "completion_date": "2027-04-24", "has_results": false, "last_update_posted_date": "2026-08-20", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 17, "location_summary": "Birmingham, Alabama • Los Angeles, California • San Francisco, California + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Tampa", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00268385" }, { "nct_id": "NCT00068510", "title": "Vaccine Therapy in Treating Patients With Malignant Glioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Brain and Central Nervous System Tumors" ], "interventions": [ { "name": "therapeutic autologous dendritic cells", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Jonsson Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2003-06", "completion_date": "2012-09", "has_results": false, "last_update_posted_date": "2020-08-03", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00068510" }, { "nct_id": "NCT04047303", "title": "CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Astrocytoma", "Glioblastoma" ], "interventions": [ { "name": "CC-90010", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Celgene", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2020-01-02", "completion_date": "2024-06-03", "has_results": false, "last_update_posted_date": "2024-07-05", "last_synced_at": "2026-10-04T01:37:59.244Z", "location_count": 2, "location_summary": "Tampa, Florida • Boston, Massachusetts", "locations": [ { "city": "Tampa", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04047303" } ] }