{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Graves+Disease&page=3", "query": { "condition": "Graves Disease", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 84, "total_pages": 9, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Graves+Disease&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Graves+Disease&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-21T03:08:37.852Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07753603", "title": "Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Thyroid Eye Disease, TED", "Graves Orbitopathy" ], "interventions": [ { "name": "linsitinib", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sling Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 130, "start_date": "2026-08-04", "completion_date": "2030-06-28", "has_results": false, "last_update_posted_date": "2026-10-20", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 18, "location_summary": "Glendale, Arizona • Beverly Hills, California • Canoga Park, California + 15 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Canoga Park", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07753603" }, { "nct_id": "NCT00424151", "title": "Rituximab Treatment of Graves' Dysthyroid Ophthalmopathy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Graves' Dysthyroid Ophthalmopathy", "Thyroid Related Orbitopathy" ], "interventions": [ { "name": "Rituximab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Silkiss, Rona Z., M.D., FACS", "sponsor_class": "INDIV", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 12, "start_date": "2006-12", "completion_date": "2009-03", "has_results": false, "last_update_posted_date": "2010-10-06", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 2, "location_summary": "Oakland, California • New York, New York", "locations": [ { "city": "Oakland", "state": "California" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00424151" }, { "nct_id": "NCT07018323", "title": "A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Graves' Disease" ], "interventions": [ { "name": "IMVT-1402", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Immunovant Sciences GmbH", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 210, "start_date": "2025-06-19", "completion_date": "2027-05", "has_results": false, "last_update_posted_date": "2026-08-25", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 33, "location_summary": "Tucson, Arizona • Concord, California • Aurora, Colorado + 28 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Concord", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Doral", "state": "Florida" }, { "city": "Hialeah", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07018323" }, { "nct_id": "NCT07413874", "title": "Telehealth Music Therapy for Adults With Endocrine Disorder and Depression", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Type 1 Diabetes", "Hashimoto Disease", "Graves Disease", "Addison Disease", "Autoimmune Polyglandular Syndrome Type III", "Depression", "Endocrine System Diseases" ], "interventions": [ { "name": "Telehealth Resource Oriented Music Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Appalachian State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 10, "start_date": "2026-07-16", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-07-30", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 1, "location_summary": "Boone, North Carolina", "locations": [ { "city": "Boone", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT07413874" }, { "nct_id": "NCT01616108", "title": "Bupivacaine Injection of Eye Muscles to Treat Strabismus", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Strabismus", "Esotropia", "Exotropia", "Graves Disease", "Ptosis, Eyelid" ], "interventions": [ { "name": "Bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Smith-Kettlewell Eye Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": "95 Years", "sex": "ALL", "summary": "8 Years to 95 Years" }, "enrollment_count": 120, "start_date": "2012-04", "completion_date": "2020-09", "has_results": false, "last_update_posted_date": "2019-09-23", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01616108" }, { "nct_id": "NCT06179875", "title": "An Open-label Study (OLE) for Non-responders of VRDN-001-101 and VRDN-001-301", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Thyroid Eye Disease" ], "interventions": [ { "name": "Veligrotug", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Viridian Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 139, "start_date": "2024-01-31", "completion_date": "2025-06-23", "has_results": true, "last_update_posted_date": "2026-08-14", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 18, "location_summary": "Los Angeles, California • Newport Beach, California • Palo Alto, California + 13 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06179875" }, { "nct_id": "NCT07369063", "title": "Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Graves Disease", "Graves' Disease", "Hyperthyroidism" ], "interventions": [ { "name": "Ergocalciferol 50,000 IU", "type": "DRUG" }, { "name": "Methimazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "9 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "9 Years to 17 Years" }, "enrollment_count": 30, "start_date": "2025-08-01", "completion_date": "2027-02-28", "has_results": false, "last_update_posted_date": "2026-01-27", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 1, "location_summary": "New Hyde Park, New York", "locations": [ { "city": "New Hyde Park", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07369063" }, { "nct_id": "NCT05635266", "title": "Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Age-Related Macular Degeneration", "Allergies", "Alpha-Gal Syndrome", "Alzheimer Disease", "Amyloidosis", "Ankylosing Spondylitis", "Arthritis", "Alopecia Areata", "Asthma", "Atopic Dermatitis", "Autism", "Autoimmune Hepatitis", "Behcet's Disease", "Beta-Thalassemia", "Cancer", "Celiac Disease", "Kidney Diseases", "COPD", "Crohn Disease", "Cystic Fibrosis", "Diabetes", "Dravet Syndrome", "DMD", "Fibromyalgia", "Graves Disease", "Thyroid Diseases", "Hepatitis", "Hidradenitis Suppurativa", "ITP", "Leukemia", "ALS", "Lupus or SLE", "Lymphoma", "Multiple Sclerosis", "Myasthenia Gravis", "Heart Diseases", "Parkinson Disease", "Pemphigus Vulgaris", "Cirrhosis", "Psoriasis", "Schizophrenia", "Scleroderma", "Sickle Cell Disease", "Stroke", "Ulcerative Colitis", "Vasculitis", "Vitiligo" ], "interventions": [ { "name": "Specimen sample", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Sanguine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 20000, "start_date": "2021-10-26", "completion_date": "2025-10", "has_results": false, "last_update_posted_date": "2024-05-07", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 1, "location_summary": "Waltham, Massachusetts", "locations": [ { "city": "Waltham", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05635266" }, { "nct_id": "NCT04311606", "title": "Anti-VEGF Therapy for Acute Thyroid Eye Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Thyroid Eye Disease" ], "interventions": [ { "name": "Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept", "type": "DRUG" }, { "name": "Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept", "type": "DRUG" }, { "name": "Sub-tenon injection of hyaluronidase (HA) alone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts Eye and Ear Infirmary", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2020-11-02", "completion_date": "2024-12-17", "has_results": true, "last_update_posted_date": "2026-10-20", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04311606" }, { "nct_id": "NCT01927406", "title": "The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Thyroid Eye Disease", "Ocular Hypertension", "Glaucoma" ], "interventions": [ { "name": "Prostaglandin Analog", "type": "DRUG" }, { "name": "Timolol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2014-06", "completion_date": "2016-12", "has_results": false, "last_update_posted_date": "2018-05-15", "last_synced_at": "2026-10-21T03:08:37.852Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01927406" } ] }