{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Great+Saphenous+Vein+Incompetence",
    "query": {
      "condition": "Great Saphenous Vein Incompetence"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Great+Saphenous+Vein+Incompetence&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T06:05:45.192Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02236338",
      "title": "Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous Vein",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Ablation of the Incompetent Greater Saphenous Vein",
          "type": "PROCEDURE"
        },
        {
          "name": "ClosureFAST radiofrequency catheter",
          "type": "DEVICE"
        },
        {
          "name": "EVLT 980nm diode laser system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2008-09",
      "completion_date": "2016-08-11",
      "has_results": true,
      "last_update_posted_date": "2018-05-14",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02236338"
    },
    {
      "nct_id": "NCT05926830",
      "title": "Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Sonovein Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Theraclion",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2023-10-12",
      "completion_date": "2025-06-11",
      "has_results": false,
      "last_update_posted_date": "2025-06-19",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 2,
      "location_summary": "Englewood, New Jersey • Lake Success, New York",
      "locations": [
        {
          "city": "Englewood",
          "state": "New Jersey"
        },
        {
          "city": "Lake Success",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05926830"
    },
    {
      "nct_id": "NCT07699796",
      "title": "Apixaban vs Rivaroxaban vs No Anticoagulant to Prevent EHIT After Great Saphenous Vein Laser Ablation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Venous Thrombosis Deep (Limbs)",
        "Venous Insufficiency (Chronic)(Peripheral)",
        "Varicose Veins Leg",
        "Venous Thrombosis"
      ],
      "interventions": [
        {
          "name": "Apixaban",
          "type": "DRUG"
        },
        {
          "name": "Rivaroxaban",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Heart, Artery, and Vein Center of Fresno",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 564,
      "start_date": "2018-03-06",
      "completion_date": "2021-06-15",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 1,
      "location_summary": "Fresno, California",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07699796"
    },
    {
      "nct_id": "NCT01173419",
      "title": "Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Varicose Veins",
        "Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "VNUS RF ClosureFAST",
          "type": "DEVICE"
        },
        {
          "name": "VenaCure EVLT NeverTouch",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Angiodynamics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2010-07",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2012-07-13",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 6,
      "location_summary": "Sacramento, California • Bradenton, Florida • Melrose Park, Illinois + 3 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Melrose Park",
          "state": "Illinois"
        },
        {
          "city": "Novi",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01173419"
    },
    {
      "nct_id": "NCT01428076",
      "title": "Pharmacokinetic Study of Polidocanol Endovenous Microfoam (PEM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Varicose Veins"
      ],
      "interventions": [
        {
          "name": "Polidocanol Endovenous Microfoam (PEM)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 21,
      "start_date": "2011-08",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 1,
      "location_summary": "Bradenton, Florida",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01428076"
    },
    {
      "nct_id": "NCT01197833",
      "title": "Endovenous Ablation With and Without Polidocanol Endovenous Microfoam Treatment for Patients With Great Saphenous Vein Incompetence and Visible Varicosities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Great Saphenous Vein Incompetence",
        "Visible Varicosities"
      ],
      "interventions": [
        {
          "name": "endovenous ablation+polidocanol injectable microfoam 0.125%",
          "type": "DRUG"
        },
        {
          "name": "Endovenous ablation+polidocanol injectable microfoam 1.0%",
          "type": "DRUG"
        },
        {
          "name": "Endovenous ablation+polidocanol injectable foam 2.0%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 117,
      "start_date": "2010-09",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 7,
      "location_summary": "Scottsdale, Arizona • Bradenton, Florida • Oak Brook, Illinois + 4 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Oak Brook",
          "state": "Illinois"
        },
        {
          "city": "North Tonawanda",
          "state": "New York"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01197833"
    },
    {
      "nct_id": "NCT05312970",
      "title": "Varithena Versus Endothermal Ablation of the Great Saphenous Vein (VERITAS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Varicose Veins"
      ],
      "interventions": [
        {
          "name": "Varithena®",
          "type": "DRUG"
        },
        {
          "name": "FDA-approved Endothermal Ablation (ETA) systems",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2023-02-10",
      "completion_date": "2024-04-04",
      "has_results": true,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 9,
      "location_summary": "Darien, Connecticut • Washington D.C., District of Columbia • Houma, Louisiana + 6 more",
      "locations": [
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Houma",
          "state": "Louisiana"
        },
        {
          "city": "South Portland",
          "state": "Maine"
        },
        {
          "city": "Englewood",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05312970"
    },
    {
      "nct_id": "NCT02248740",
      "title": "Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Ablation of the incompetent small saphenous vein",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2008-09",
      "completion_date": "2017-03-29",
      "has_results": true,
      "last_update_posted_date": "2019-02-07",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02248740"
    },
    {
      "nct_id": "NCT02585726",
      "title": "Lake Washington Vascular VenaSeal™ Post-Market Evaluation (WAVES)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Reflux"
      ],
      "interventions": [
        {
          "name": "SP-402 VenaSeal™ Closure System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lake Washington Vascular",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2015-10",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2018-03-16",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 1,
      "location_summary": "Bellevue, Washington",
      "locations": [
        {
          "city": "Bellevue",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02585726"
    },
    {
      "nct_id": "NCT03820947",
      "title": "VenaSeal Spectrum: Global Post-Market Randomized Controlled Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Reflux"
      ],
      "interventions": [
        {
          "name": "VenaSeal™ System",
          "type": "DEVICE"
        },
        {
          "name": "Endothermal Ablation (ETA)",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Stripping",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Medtronic Endovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 506,
      "start_date": "2020-02-05",
      "completion_date": "2025-11-10",
      "has_results": true,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-07-24T06:05:45.192Z",
      "location_count": 12,
      "location_summary": "Prescott Valley, Arizona • Tucson, Arizona • Fresno, California + 9 more",
      "locations": [
        {
          "city": "Prescott Valley",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03820947"
    }
  ]
}