{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Great+Saphenous+Vein+Insufficiency",
    "query": {
      "condition": "Great Saphenous Vein Insufficiency"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Great+Saphenous+Vein+Insufficiency&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T09:22:51.187Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02248740",
      "title": "Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Ablation of the incompetent small saphenous vein",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2008-09",
      "completion_date": "2017-03-29",
      "has_results": true,
      "last_update_posted_date": "2019-02-07",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02248740"
    },
    {
      "nct_id": "NCT01428076",
      "title": "Pharmacokinetic Study of Polidocanol Endovenous Microfoam (PEM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Varicose Veins"
      ],
      "interventions": [
        {
          "name": "Polidocanol Endovenous Microfoam (PEM)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 21,
      "start_date": "2011-08",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 1,
      "location_summary": "Bradenton, Florida",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01428076"
    },
    {
      "nct_id": "NCT05193643",
      "title": "Minimally Invasive Treatment of Primary Great Saphenous Vein (GSV) Insufficiency Using High Intensity Focused Ultrasound (HIFU)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Great Saphenous Vein Insufficiency"
      ],
      "interventions": [
        {
          "name": "Sonovein Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Englewood Hospital and Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2022-03-23",
      "completion_date": "2023-01-31",
      "has_results": false,
      "last_update_posted_date": "2023-04-19",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 1,
      "location_summary": "Englewood, New Jersey",
      "locations": [
        {
          "city": "Englewood",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05193643"
    },
    {
      "nct_id": "NCT05926830",
      "title": "Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Sonovein Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Theraclion",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2023-10-12",
      "completion_date": "2025-06-11",
      "has_results": false,
      "last_update_posted_date": "2025-06-19",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 2,
      "location_summary": "Englewood, New Jersey • Lake Success, New York",
      "locations": [
        {
          "city": "Englewood",
          "state": "New Jersey"
        },
        {
          "city": "Lake Success",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05926830"
    },
    {
      "nct_id": "NCT02236338",
      "title": "Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous Vein",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Ablation of the Incompetent Greater Saphenous Vein",
          "type": "PROCEDURE"
        },
        {
          "name": "ClosureFAST radiofrequency catheter",
          "type": "DEVICE"
        },
        {
          "name": "EVLT 980nm diode laser system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2008-09",
      "completion_date": "2016-08-11",
      "has_results": true,
      "last_update_posted_date": "2018-05-14",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02236338"
    },
    {
      "nct_id": "NCT01173419",
      "title": "Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Varicose Veins",
        "Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "VNUS RF ClosureFAST",
          "type": "DEVICE"
        },
        {
          "name": "VenaCure EVLT NeverTouch",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Angiodynamics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2010-07",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2012-07-13",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 6,
      "location_summary": "Sacramento, California • Bradenton, Florida • Melrose Park, Illinois + 3 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Melrose Park",
          "state": "Illinois"
        },
        {
          "city": "Novi",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01173419"
    },
    {
      "nct_id": "NCT03820947",
      "title": "VenaSeal Spectrum: Global Post-Market Randomized Controlled Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Reflux"
      ],
      "interventions": [
        {
          "name": "VenaSeal™ System",
          "type": "DEVICE"
        },
        {
          "name": "Endothermal Ablation (ETA)",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Stripping",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Medtronic Endovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 506,
      "start_date": "2020-02-05",
      "completion_date": "2025-11-10",
      "has_results": true,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 12,
      "location_summary": "Prescott Valley, Arizona • Tucson, Arizona • Fresno, California + 9 more",
      "locations": [
        {
          "city": "Prescott Valley",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03820947"
    },
    {
      "nct_id": "NCT04006184",
      "title": "Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal Ablation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Varicose Veins",
        "Venous Reflux",
        "Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Chart review",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Lake Washington Vascular",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 547,
      "start_date": "2019-06-14",
      "completion_date": "2019-08-30",
      "has_results": false,
      "last_update_posted_date": "2019-10-03",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 1,
      "location_summary": "Bellevue, Washington",
      "locations": [
        {
          "city": "Bellevue",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04006184"
    },
    {
      "nct_id": "NCT05504070",
      "title": "Venclose digiRF System Post Market Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Reflux",
        "Chronic Venous Insufficiency"
      ],
      "interventions": [
        {
          "name": "Venclose System (digiRF generator w EVSRF catheter)",
          "type": "DEVICE"
        },
        {
          "name": "Venclose MAVEN System (digiRF generator w MAVEN catheter)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "C. R. Bard",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 203,
      "start_date": "2023-09-08",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 7,
      "location_summary": "Thornton, Colorado • Kailua, Hawaii • Roseville, Michigan + 4 more",
      "locations": [
        {
          "city": "Thornton",
          "state": "Colorado"
        },
        {
          "city": "Kailua",
          "state": "Hawaii"
        },
        {
          "city": "Roseville",
          "state": "Michigan"
        },
        {
          "city": "Englewood",
          "state": "New Jersey"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05504070"
    },
    {
      "nct_id": "NCT01197833",
      "title": "Endovenous Ablation With and Without Polidocanol Endovenous Microfoam Treatment for Patients With Great Saphenous Vein Incompetence and Visible Varicosities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Great Saphenous Vein Incompetence",
        "Visible Varicosities"
      ],
      "interventions": [
        {
          "name": "endovenous ablation+polidocanol injectable microfoam 0.125%",
          "type": "DRUG"
        },
        {
          "name": "Endovenous ablation+polidocanol injectable microfoam 1.0%",
          "type": "DRUG"
        },
        {
          "name": "Endovenous ablation+polidocanol injectable foam 2.0%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 117,
      "start_date": "2010-09",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-07-23T09:22:51.187Z",
      "location_count": 7,
      "location_summary": "Scottsdale, Arizona • Bradenton, Florida • Oak Brook, Illinois + 4 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Oak Brook",
          "state": "Illinois"
        },
        {
          "city": "North Tonawanda",
          "state": "New York"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01197833"
    }
  ]
}