{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gum+Disease",
    "query": {
      "condition": "Gum Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 451,
    "total_pages": 46,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gum+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T08:11:10.156Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01770470",
      "title": "Chitosan Chewing Gum Study in Dialysis Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Chitosan",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 15,
      "start_date": "2010-04",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2021-06-23",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01770470"
    },
    {
      "nct_id": "NCT06659471",
      "title": "Brief Title: a Clinical Study to Assess Gingivitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Diseases"
      ],
      "interventions": [
        {
          "name": "0.76% Sodium Monofluorophosphate Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "0.454% Stannous Fluoride Dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2022-03-07",
      "completion_date": "2022-06-06",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06659471"
    },
    {
      "nct_id": "NCT01330719",
      "title": "Mechanisms and Treatment Response of Aggressive Periodontitis in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aggressive Periodontitis"
      ],
      "interventions": [
        {
          "name": "Diseased periodontal treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Conventional periodontal treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "5 Years to 90 Years"
      },
      "enrollment_count": 514,
      "start_date": "2006-12",
      "completion_date": "2022-12-02",
      "has_results": false,
      "last_update_posted_date": "2024-03-12",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 10,
      "location_summary": "Brooker, Florida • Fort Lauderdale, Florida • Gainesville, Florida + 6 more",
      "locations": [
        {
          "city": "Brooker",
          "state": "Florida"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Hialeah",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01330719"
    },
    {
      "nct_id": "NCT06966492",
      "title": "Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingival Inflammation"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Toothpaste (SnF)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-06",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-26",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06966492"
    },
    {
      "nct_id": "NCT01215201",
      "title": "Diode Laser Study for Periodontal Maintenance Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontal Diseases",
        "Periodontitis, Apical, Chronic Nonsuppurative",
        "Suppuration of Gingival Crevice"
      ],
      "interventions": [
        {
          "name": "Scaling and Root Planing",
          "type": "PROCEDURE"
        },
        {
          "name": "Diode Laser + Scaling and Root Planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2010-05-01",
      "completion_date": "2011-07-01",
      "has_results": false,
      "last_update_posted_date": "2023-09-15",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01215201"
    },
    {
      "nct_id": "NCT00798031",
      "title": "Case Series Evaluation of a Short Dental Implant",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Loss"
      ],
      "interventions": [
        {
          "name": "A minimum of two but up to three Astra Tech Dental Implant, Fixture Osseospeed will be placed in the posterior upper jaw of 20 eligible subjects.",
          "type": "DEVICE"
        },
        {
          "name": "Placement of dental implant",
          "type": "DEVICE"
        },
        {
          "name": "dental implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Clark Stanford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 0,
      "start_date": "2008-10",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00798031"
    },
    {
      "nct_id": "NCT00223327",
      "title": "Measurement of Bite Force in Humans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Pulp Necrosis",
        "Periapical Periodontitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "16 Years to 60 Years"
      },
      "enrollment_count": 89,
      "start_date": "2005-03",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2012-03-09",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00223327"
    },
    {
      "nct_id": "NCT04210375",
      "title": "Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Failure With Reduced Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "JK07",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Salubris Biotherapeutics Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 14,
      "start_date": "2020-09-21",
      "completion_date": "2023-07-07",
      "has_results": true,
      "last_update_posted_date": "2025-07-09",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 7,
      "location_summary": "Tucson, Arizona • Stanford, California • Boston, Massachusetts + 4 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04210375"
    },
    {
      "nct_id": "NCT01156155",
      "title": "Periodontal Disease and P. Gingivalis in Rheumatoid Arthritis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rheumatoid Arthritis",
        "Osteoarthritis",
        "Periodontal Disease"
      ],
      "interventions": [
        {
          "name": "Digital xray of jaw and teeth",
          "type": "RADIATION"
        },
        {
          "name": "Blood draw",
          "type": "PROCEDURE"
        },
        {
          "name": "questionnaires",
          "type": "OTHER"
        },
        {
          "name": "Periodontal Examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Bilateral digital xray of hands",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 617,
      "start_date": "2010-07-14",
      "completion_date": "2018-08-30",
      "has_results": false,
      "last_update_posted_date": "2023-11-02",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01156155"
    },
    {
      "nct_id": "NCT01878071",
      "title": "The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obesity",
        "Peri-implant Inflammation",
        "Peri-implantitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 73,
      "start_date": "2012-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-05-20",
      "last_synced_at": "2026-06-26T08:11:10.156Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01878071"
    }
  ]
}