{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gut+Permeability%2C+Gut+Inflammation",
    "query": {
      "condition": "Gut Permeability, Gut Inflammation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gut+Permeability%2C+Gut+Inflammation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T08:28:33.941Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07650058",
      "title": "Postprandial Effects of Fresh Mango as a Table Sugar Replacement in High-Sugar Breakfasts.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Participants"
      ],
      "interventions": [
        {
          "name": "High-Glycemic Breakfast Containing Cereal and Fresh Mango",
          "type": "OTHER"
        },
        {
          "name": "High-Glycemic Breakfast Containing Cereal and Table Sugar",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ball State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 35,
      "start_date": "2026-02-01",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Muncie, Indiana",
      "locations": [
        {
          "city": "Muncie",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07650058"
    },
    {
      "nct_id": "NCT01155492",
      "title": "Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson's Disease",
        "Multiple System Atrophy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2007-09",
      "completion_date": "2013-02",
      "has_results": false,
      "last_update_posted_date": "2013-05-30",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01155492"
    },
    {
      "nct_id": "NCT01477034",
      "title": "Vitamin D and Adipose Tissue Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vitamin D Deficiency",
        "Obesity",
        "Type 2 Diabetes Mellitus",
        "Intestinal Permeability"
      ],
      "interventions": [
        {
          "name": "Vitamin D3",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 18,
      "start_date": "2011-11",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2014-04-04",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01477034"
    },
    {
      "nct_id": "NCT05318183",
      "title": "Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PreDiabetes",
        "Dysbiosis",
        "Endotoxemia",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Whole Wheat Bread",
          "type": "OTHER"
        },
        {
          "name": "White Bread (control)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 65,
      "start_date": "2022-01-27",
      "completion_date": "2026-05-30",
      "has_results": true,
      "last_update_posted_date": "2025-11-20",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05318183"
    },
    {
      "nct_id": "NCT07387991",
      "title": "Evaluating the Ability of a Multi-Strain Postbiotic to Impact Inflammation, Immune Components, Gastrointestinal Symptoms, Recovery, Anxiety, and Intestinal Permeability",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inflammation",
        "Gastrointestinal Symptoms"
      ],
      "interventions": [
        {
          "name": "Multi-Strain Postbiotic",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Lindenwood University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 50,
      "start_date": "2026-06-01",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Saint Charles, Missouri",
      "locations": [
        {
          "city": "Saint Charles",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07387991"
    },
    {
      "nct_id": "NCT06501898",
      "title": "Tributyrin: Time Course & Efficacy to Improve Health & Performance",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolite Concentration",
        "Gut Permeability",
        "Inflammation",
        "Sleep",
        "Performance"
      ],
      "interventions": [
        {
          "name": "CoreBiome",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "30 Years to 50 Years"
      },
      "enrollment_count": 4,
      "start_date": "2024-08-19",
      "completion_date": "2025-03-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-13",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06501898"
    },
    {
      "nct_id": "NCT01424306",
      "title": "Diet and Systemic Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low-grade Chronic Inflammation",
        "Intestinal Permeability",
        "Type 2 Diabetes Mellitus",
        "Cardiovascular Disease",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Fructose-sweetened beverages",
          "type": "OTHER"
        },
        {
          "name": "Glucose-sweetened beverages",
          "type": "OTHER"
        },
        {
          "name": "High-fructose corn syrup-sweetened beverages",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 25,
      "start_date": "2011-10",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2017-08-14",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01424306"
    },
    {
      "nct_id": "NCT03427879",
      "title": "Effect of Flavonoids on Gut Permeability in Cyclists",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gut Permeability, Gut Inflammation"
      ],
      "interventions": [
        {
          "name": "Low flavonoid beverage",
          "type": "DRUG"
        },
        {
          "name": "High flavonoid beverage",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Utah State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 12,
      "start_date": "2018-09-14",
      "completion_date": "2019-07-31",
      "has_results": false,
      "last_update_posted_date": "2021-02-25",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Logan, Utah",
      "locations": [
        {
          "city": "Logan",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03427879"
    },
    {
      "nct_id": "NCT05308394",
      "title": "Gut Permeability-related Inflammation and Cardiovascular Disease Risk in Normal-weight and Metabolically Healthy Obesity",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "No experimental intervention will take place - the study is cross-sectional. Each participant will provide biological samples.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oklahoma State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-03-10",
      "completion_date": "2022-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-04-15",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Stillwater, Oklahoma",
      "locations": [
        {
          "city": "Stillwater",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05308394"
    },
    {
      "nct_id": "NCT04543877",
      "title": "WHNRC (Western Human Nutrition Research Center) Fiber Intervention Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Inflammation",
        "Vaccine",
        "Intestinal Permeability",
        "Typhoid Fever"
      ],
      "interventions": [
        {
          "name": "Inulin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Maltodextrin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Ty21a Typhoid Fever Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BIOLOGICAL"
      ],
      "sponsor": "USDA, Western Human Nutrition Research Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "18 Years to 59 Years"
      },
      "enrollment_count": 60,
      "start_date": "2022-09-27",
      "completion_date": "2025-06-11",
      "has_results": false,
      "last_update_posted_date": "2025-12-17",
      "last_synced_at": "2026-07-24T08:28:33.941Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04543877"
    }
  ]
}