{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=HBOC+Syndrome&page=2",
    "query": {
      "condition": "HBOC Syndrome",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=HBOC+Syndrome&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T09:19:31.527Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03421327",
      "title": "Genetic Risk: Whether, When, and How to Tell Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Huntington Disease",
        "Hereditary Breast and Ovarian Cancer",
        "Hereditary Cancer",
        "Hereditary Non-polyposis Colon Cancer",
        "Hereditary Non-Polyposis Colorectal Cancer Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2017-09-01",
      "completion_date": "2018-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-02-07",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03421327"
    },
    {
      "nct_id": "NCT00829959",
      "title": "Attitudes About Childbearing And Fertility With Inherited Breast And Ovarian Cancer Syndromes (HBOC)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer",
        "Ovarian Cancer"
      ],
      "interventions": [
        {
          "name": "Questionnaire",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 156,
      "start_date": "2009-02",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2016-08-04",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00829959"
    },
    {
      "nct_id": "NCT01273909",
      "title": "Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer",
        "Hereditary Breast/Ovarian Cancer (brca1, brca2)",
        "Acquired Lymphedema",
        "Congenital Lymphedema"
      ],
      "interventions": [
        {
          "name": "Perforator Flap Breast Reconstruction",
          "type": "PROCEDURE"
        },
        {
          "name": "Vascularized Lymph Node Transfer",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The National Institute of Lymphology",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2010-07",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2014-06-06",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • New Orleans, Louisiana • Charleston, South Carolina",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01273909"
    },
    {
      "nct_id": "NCT03959267",
      "title": "Testing a Culturally Adapted Telephone Genetic Counseling Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Hereditary Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Telephone Genetic Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 90 Years · Female only"
      },
      "enrollment_count": 37,
      "start_date": "2017-07-07",
      "completion_date": "2021-01-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-01",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 4,
      "location_summary": "Washington D.C., District of Columbia • Hackensack, New Jersey • Alexandria, Virginia + 1 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Hackensack",
          "state": "New Jersey"
        },
        {
          "city": "Alexandria",
          "state": "Virginia"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03959267"
    },
    {
      "nct_id": "NCT03832985",
      "title": "Pediatric Reporting of Adult-Onset Genomic Results",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Hereditary Breast and Ovarian Cancer Syndrome",
        "Lynch Syndrome",
        "Familial Hypercholesterolemia"
      ],
      "interventions": [
        {
          "name": "Child(ren) receive an adult-onset result",
          "type": "GENETIC"
        },
        {
          "name": "Child(ren) received a pediatric-onset result",
          "type": "GENETIC"
        },
        {
          "name": "Control - Negative Result",
          "type": "GENETIC"
        },
        {
          "name": "Adolescents who received adult-onset result",
          "type": "GENETIC"
        },
        {
          "name": "Adolescents who received a pediatric-onset result",
          "type": "GENETIC"
        },
        {
          "name": "Adolescent controls - negative for familial variant",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Geisinger Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 162,
      "start_date": "2020-11-25",
      "completion_date": "2024-10-31",
      "has_results": true,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 1,
      "location_summary": "Danville, Pennsylvania",
      "locations": [
        {
          "city": "Danville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03832985"
    },
    {
      "nct_id": "NCT04494945",
      "title": "Identifying and Caring for Individuals With Inherited Cancer Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome",
        "Breast Ductal Carcinoma In Situ",
        "Hematopoietic and Lymphoid System Neoplasm",
        "Hereditary Neoplastic Syndrome",
        "Lynch Syndrome",
        "Malignant Solid Neoplasm"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Genetic Counseling",
          "type": "OTHER"
        },
        {
          "name": "Genetic Testing",
          "type": "OTHER"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "OHSU Knight Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27500,
      "start_date": "2020-03-09",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04494945"
    },
    {
      "nct_id": "NCT04508764",
      "title": "Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hereditary Breast and Ovarian Cancer",
        "Lynch Syndrome"
      ],
      "interventions": [
        {
          "name": "Families Accelerating Cascade Testing Toolkit",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2021-04-09",
      "completion_date": "2024-03-20",
      "has_results": false,
      "last_update_posted_date": "2024-04-16",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04508764"
    },
    {
      "nct_id": "NCT02786147",
      "title": "Identification and Referral of Women at Risk for Hereditary Breast/Ovarian Cancer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hereditary Breast and Ovarian Cancer"
      ],
      "interventions": [
        {
          "name": "Breast Cancer Genetics Referral Screening Tool 3.0",
          "type": "OTHER"
        },
        {
          "name": "Standard Handout",
          "type": "OTHER"
        },
        {
          "name": "Physician Notification",
          "type": "OTHER"
        },
        {
          "name": "Automatic Follow-Up by Genetic Counseling Staff",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 665,
      "start_date": "2016-04",
      "completion_date": "2018-02-28",
      "has_results": false,
      "last_update_posted_date": "2018-04-20",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02786147"
    },
    {
      "nct_id": "NCT00609505",
      "title": "Telemedicine vs. Face-to-Face Cancer Genetic Counseling",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hereditary Breast and Ovarian Cancer Syndrome",
        "Lynch Syndrome"
      ],
      "interventions": [
        {
          "name": "Telemedicine",
          "type": "OTHER"
        },
        {
          "name": "Face-to-Face",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2008-08",
      "completion_date": "2011-04",
      "has_results": false,
      "last_update_posted_date": "2012-02-22",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 4,
      "location_summary": "Henderson, North Carolina • Laurinburg, North Carolina • Lumberton, North Carolina + 1 more",
      "locations": [
        {
          "city": "Henderson",
          "state": "North Carolina"
        },
        {
          "city": "Laurinburg",
          "state": "North Carolina"
        },
        {
          "city": "Lumberton",
          "state": "North Carolina"
        },
        {
          "city": "Smithfield",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00609505"
    },
    {
      "nct_id": "NCT00535119",
      "title": "Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Adult Solid Neoplasm",
        "BRCA1 Mutation Carrier",
        "BRCA2 Mutation Carrier",
        "Hereditary Breast and Ovarian Cancer Syndrome"
      ],
      "interventions": [
        {
          "name": "Carboplatin",
          "type": "DRUG"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Paclitaxel",
          "type": "DRUG"
        },
        {
          "name": "Pharmacological Study",
          "type": "OTHER"
        },
        {
          "name": "Veliparib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2007-09",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2015-05-22",
      "last_synced_at": "2026-07-23T09:19:31.527Z",
      "location_count": 7,
      "location_summary": "Duarte, California • Los Angeles, California • Sacramento, California + 3 more",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00535119"
    }
  ]
}