{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=HPV-Related+Carcinoma&page=3", "query": { "condition": "HPV-Related Carcinoma", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 80, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=HPV-Related+Carcinoma&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=HPV-Related+Carcinoma&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-03T18:11:41.432Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04900623", "title": "Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HPV-Associated Oropharyngeal Squamous Cell Carcinoma", "HPV Positive Oropharyngeal Squamous Cell Carcinoma", "HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage", "HPV-Related Squamous Cell Carcinoma", "Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage", "HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Pathologic Stage" ], "interventions": [ { "name": "NavDx HPV ctDNA Testing", "type": "DEVICE" }, { "name": "Radiotherapy", "type": "RADIATION" }, { "name": "Chemotherapy drug", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "RADIATION", "DRUG" ], "sponsor": "Jonathan Schoenfeld, MD, MPH", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 145, "start_date": "2021-07-02", "completion_date": "2032-06-01", "has_results": false, "last_update_posted_date": "2026-08-05", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 2, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04900623" }, { "nct_id": "NCT06949800", "title": "CASCADE 2002: PROTECT Study, \"PRObiotics to TrEat Anal preCancer Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HSIL, High Grade Squamous Intraepithelial Lesion", "HPV-Related Squamous Cell Carcinoma", "Anal HSIL" ], "interventions": [ { "name": "EXE-346 Probiotic", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Usual Care High Resolution Anoscopy (HRA)", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 90, "start_date": "2026-09-04", "completion_date": "2028-05-31", "has_results": false, "last_update_posted_date": "2026-09-15", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06949800" }, { "nct_id": "NCT06651957", "title": "Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Human Immunodeficiency Virus", "Human Papillomavirus-Related Anal Squamous Cell Carcinoma", "High-Grade Squamous Intraepithelial Lesions" ], "interventions": [ { "name": "Biospecimen Collection", "type": "OTHER" }, { "name": "Questionnaires", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 217, "start_date": "2024-10-31", "completion_date": "2027-05-01", "has_results": false, "last_update_posted_date": "2026-08-20", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06651957" }, { "nct_id": "NCT04452526", "title": "I Vaccinate: Testing Multi-Level Interventions to Improve HPV Vaccination", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cervical Carcinoma", "Human Papillomavirus-Related Malignant Neoplasm" ], "interventions": [ { "name": "Best Practice", "type": "OTHER" }, { "name": "Educational Intervention", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Reminder", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "11 Years", "maximum_age": null, "sex": "ALL", "summary": "11 Years and older" }, "enrollment_count": 372, "start_date": "2020-10-21", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-06-15", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 4, "location_summary": "Lexington, Kentucky • Columbus, Ohio • Charlottesville, Virginia + 1 more", "locations": [ { "city": "Lexington", "state": "Kentucky" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Charlottesville", "state": "Virginia" }, { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04452526" }, { "nct_id": "NCT05075993", "title": "Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Metastatic Esophageal", "Gastric Cancer", "Metastatic Head and Neck Carcinoma", "Metastatic Hepatocellular Carcinoma", "Metastatic HPV Related Solid Tumors", "Metastatic Ovarian Carcinoma", "Metastatic Soft Tissue Sarcoma", "Metastatic Uveal Melanoma" ], "interventions": [ { "name": "LVGN3616 + LVGN6051 + Nab-Paclitaxel", "type": "DRUG" }, { "name": "LVGN3616 + LVGN6051 + Bevacizumab + Cyclophosphamide", "type": "DRUG" }, { "name": "LVGN3616 + LVGN6051 + LVGN7409 + Nab-Paclitaxel", "type": "DRUG" }, { "name": "LVGN3616 + LVGN6051 + LVGN7409 + Bevacizumab + Cyclophosphamide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 352, "start_date": "2021-11-12", "completion_date": "2027-02-02", "has_results": false, "last_update_posted_date": "2026-06-12", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05075993" }, { "nct_id": "NCT03634267", "title": "MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Human Papillomavirus-Related Carcinoma", "Human Papillomavirus-Related Cervical Carcinoma", "Stage IB2 Cervical Cancer AJCC v8", "Stage II Cervical Cancer AJCC v8", "Stage II Vaginal Cancer AJCC v8", "Stage IIA Cervical Cancer AJCC v8", "Stage IIA Vaginal Cancer AJCC v8", "Stage IIA1 Cervical Cancer AJCC v8", "Stage IIA2 Cervical Cancer AJCC v8", "Stage IIB Cervical Cancer AJCC v8", "Stage IIB Vaginal Cancer AJCC v8", "Stage III Cervical Cancer AJCC v8", "Stage III Vaginal Cancer AJCC v8", "Stage IIIA Cervical Cancer AJCC v8", "Stage IIIB Cervical Cancer AJCC v8", "Stage IVA Cervical Cancer AJCC v8", "Stage IVA Vaginal Cancer AJCC v8" ], "interventions": [ { "name": "Internal Radiation Therapy", "type": "RADIATION" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" } ], "intervention_types": [ "RADIATION", "PROCEDURE" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 26, "start_date": "2018-08-03", "completion_date": "2026-08-26", "has_results": false, "last_update_posted_date": "2026-09-15", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03634267" }, { "nct_id": "NCT06305676", "title": "Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Oropharyngeal Cancer", "HPV-Related Carcinoma" ], "interventions": [ { "name": "combined HPV 16 DNA and host gene methylation oral biomarker panel", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "H. Lee Moffitt Cancer Center and Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2024-01-22", "completion_date": "2029-01", "has_results": false, "last_update_posted_date": "2026-09-23", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 3, "location_summary": "Tampa, Florida • Omaha, Nebraska • Pittsburgh, Pennsylvania", "locations": [ { "city": "Tampa", "state": "Florida" }, { "city": "Omaha", "state": "Nebraska" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT06305676" }, { "nct_id": "NCT04920344", "title": "Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8", "Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma" ], "interventions": [ { "name": "Transoral Surgery", "type": "PROCEDURE" }, { "name": "External Beam Radiation Therapy", "type": "RADIATION" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Incisional Tumor Biopsy", "type": "PROCEDURE" }, { "name": "Circulating tumor deoxyribonucleic acid (ctDNA) levels assessment", "type": "OTHER" }, { "name": "MD Anderson Dysphagia Index", "type": "OTHER" }, { "name": "University of Washington Quality of Life Questionnaire", "type": "OTHER" }, { "name": "Euro-QOL 5 dimension scale questionnaire", "type": "OTHER" }, { "name": "Modified barium swallow (MBS) evaluation with aspiration-penetration scale", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "PROCEDURE", "RADIATION", "DRUG", "OTHER", "DIAGNOSTIC_TEST" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2021-05-19", "completion_date": "2026-09", "has_results": false, "last_update_posted_date": "2026-08-14", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 3, "location_summary": "New Brunswick, New Jersey • Newark, New Jersey", "locations": [ { "city": "New Brunswick", "state": "New Jersey" }, { "city": "New Brunswick", "state": "New Jersey" }, { "city": "Newark", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT04920344" }, { "nct_id": "NCT04857528", "title": "Detecting HPV DNA in Anal and Cervical Cancers", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cervical Cancer", "Anal Cancer", "HPV-Related Anal Squamous Cell Carcinoma", "HPV-Related Cervical Carcinoma", "HPV-Related Carcinoma", "Uterine Cervical Cancer" ], "interventions": [ { "name": "Radiation Treatment With or Without Chemotherapy", "type": "RADIATION" }, { "name": "Blood Sample Collection", "type": "OTHER" }, { "name": "HPV Genotyping (HPV DNA Test)", "type": "DIAGNOSTIC_TEST" }, { "name": "Testing Archival Tumor Tissue", "type": "DIAGNOSTIC_TEST" }, { "name": "Physical Exam", "type": "OTHER" }, { "name": "Positron Emission Tomography Scan (PET Scan)/ Computed Tomography Scan (CT Scan)", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "RADIATION", "OTHER", "DIAGNOSTIC_TEST" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2020-10-06", "completion_date": "2027-11-15", "has_results": false, "last_update_posted_date": "2026-03-04", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 2, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04857528" }, { "nct_id": "NCT04880837", "title": "Human Papillomavirus Education Programs", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Human Papillomavirus-Related Carcinoma" ], "interventions": [ { "name": "Educational Intervention", "type": "OTHER" }, { "name": "Informational Intervention", "type": "OTHER" }, { "name": "Survey Administration", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 12, "start_date": "2022-04-27", "completion_date": "2022-12-31", "has_results": false, "last_update_posted_date": "2023-11-02", "last_synced_at": "2026-10-03T18:11:41.432Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04880837" } ] }