{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=HTN",
    "query": {
      "condition": "HTN"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3848,
    "total_pages": 385,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=HTN&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T16:27:26.945Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00158743",
      "title": "Efficacy Study of Digibind for Treatment of Severe Preeclampsia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pre-eclampsia"
      ],
      "interventions": [
        {
          "name": "Anti-digoxin antibody (FAB fragment)",
          "type": "DRUG"
        },
        {
          "name": "sodium chloride",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "BTG International Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 51,
      "start_date": "2004-02",
      "completion_date": "2007-12",
      "has_results": true,
      "last_update_posted_date": "2014-08-08",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 8,
      "location_summary": "Mobile, Alabama • Phoenix, Arizona • Orlando, Florida + 5 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00158743"
    },
    {
      "nct_id": "NCT03497689",
      "title": "EXPEDITE: A Study of Remodulin Induction Followed by Orenitram Optimization to Treat Pulmonary Arterial Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pulmonary Arterial Hypertension"
      ],
      "interventions": [
        {
          "name": "Intravenous/Subcutaneous Treprostinil; Oral Treprostinil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 36,
      "start_date": "2019-01-31",
      "completion_date": "2022-05-11",
      "has_results": true,
      "last_update_posted_date": "2023-08-07",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 11,
      "location_summary": "Fresno, California • Torrance, California • Orlando, Florida + 8 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Austell",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03497689"
    },
    {
      "nct_id": "NCT05280366",
      "title": "STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle Glaucoma",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Open Angle Glaucoma"
      ],
      "interventions": [
        {
          "name": "Streamline Surgical System",
          "type": "DEVICE"
        },
        {
          "name": "iStent Inject W",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "New World Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2022-02-09",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-11-12",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 18,
      "location_summary": "Fayetteville, Arkansas • Newport Beach, California • Torrance, California + 15 more",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Ocala",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05280366"
    },
    {
      "nct_id": "NCT00331188",
      "title": "Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Esophageal Varices",
        "Portal Hypertension",
        "Gastric Varices",
        "Esophageal Bleeding"
      ],
      "interventions": [
        {
          "name": "Sanvar® (vapreotide)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Debiovision",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 70,
      "start_date": "2006-05",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2008-07-08",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Montgomery, Alabama • Scottsdale, Arizona + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00331188"
    },
    {
      "nct_id": "NCT02565173",
      "title": "Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Primary Open-Angle Glaucoma (POAG)",
        "Ocular Hypertension (OHT)"
      ],
      "interventions": [
        {
          "name": "trabodenoson 4.5% BID",
          "type": "DRUG"
        },
        {
          "name": "trabodenoson 6.0% QD",
          "type": "DRUG"
        },
        {
          "name": "trabodenoson 3.0% QD",
          "type": "DRUG"
        },
        {
          "name": "timolol 0.5% BID",
          "type": "DRUG"
        },
        {
          "name": "placebo BID",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Inotek Pharmaceuticals Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 303,
      "start_date": "2015-09",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2016-12-06",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 1,
      "location_summary": "Lexington, Massachusetts",
      "locations": [
        {
          "city": "Lexington",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02565173"
    },
    {
      "nct_id": "NCT06778239",
      "title": "Childhood-Onset Essential Hypertension Natural History Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypertension",
        "Essential Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Human Genome Research Institute (NHGRI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "2 Years to 99 Years"
      },
      "enrollment_count": 2300,
      "start_date": "2025-05-30",
      "completion_date": "2034-12-09",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06778239"
    },
    {
      "nct_id": "NCT01972139",
      "title": "Renal Denervation in Patients With Uncontrolled Hypertension - SYMPLICITY HTN-4",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Vascular Diseases",
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Renal Denervation using the Symplicity Renal Denervation System",
          "type": "DEVICE"
        },
        {
          "name": "Sham Renal Denervation",
          "type": "OTHER"
        },
        {
          "name": "Renal Angiography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Medtronic Vascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 44,
      "start_date": "2013-10",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2017-04-26",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Durham, North Carolina • Charleston, South Carolina",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01972139"
    },
    {
      "nct_id": "NCT02032459",
      "title": "Vitamin D and Pregnancy: Camden Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Reproductive Effects",
        "Pregnancy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rowan University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1141,
      "start_date": "2007-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-01-10",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 1,
      "location_summary": "Stratford, New Jersey",
      "locations": [
        {
          "city": "Stratford",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02032459"
    },
    {
      "nct_id": "NCT03013179",
      "title": "Intergenerational Blood Pressure Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "3 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2015-04",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2020-03-20",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 1,
      "location_summary": "Orange, Connecticut",
      "locations": [
        {
          "city": "Orange",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03013179"
    },
    {
      "nct_id": "NCT07224542",
      "title": "Smart Soft Contact Lenses for Monitoring Glaucoma",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Bare Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "Clinical IOP Measure",
          "type": "DEVICE"
        },
        {
          "name": "Experimental Contact Lens Sensor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2025-10-19",
      "completion_date": "2028-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-05",
      "last_synced_at": "2026-07-24T16:27:26.945Z",
      "location_count": 1,
      "location_summary": "Bloomington, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07224542"
    }
  ]
}