{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Head&page=25", "query": { "condition": "Head", "page": 25 }, "page_size": 10 }, "pagination": { "page": 25, "page_size": 10, "total_count": 4252, "total_pages": 426, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Head&page=26&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Head&page=24&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-20T04:18:27.229Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03739931", "title": "Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma", "Dose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma" ], "interventions": [ { "name": "mRNA-2752", "type": "BIOLOGICAL" }, { "name": "Durvalumab", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "ModernaTX, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 134, "start_date": "2018-11-27", "completion_date": "2025-08-01", "has_results": false, "last_update_posted_date": "2025-08-15", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 16, "location_summary": "San Francisco, California • Santa Monica, California • Aurora, Colorado + 10 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Sarasota", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03739931" }, { "nct_id": "NCT03894553", "title": "Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cancer of Head and Neck", "Pain, Face", "Pain, Neck" ], "interventions": [ { "name": "ExAblate Neuro", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Jeff Elias, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 6, "start_date": "2020-06-22", "completion_date": "2025-08-31", "has_results": false, "last_update_posted_date": "2025-10-23", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 1, "location_summary": "Charlottesville, Virginia", "locations": [ { "city": "Charlottesville", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03894553" }, { "nct_id": "NCT03509012", "title": "Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Carcinoma, Squamous Cell of Head and Neck", "Carcinoma, Non-Small-Cell Lung", "Small Cell Lung Carcinoma" ], "interventions": [ { "name": "Durvalumab", "type": "DRUG" }, { "name": "Tremelimumab", "type": "DRUG" }, { "name": "Cisplatin (dose level 4)", "type": "DRUG" }, { "name": "Cisplatin (dose level 3)", "type": "DRUG" }, { "name": "Carboplatin (dose level 1)", "type": "DRUG" }, { "name": "Carboplatin (dose level 2)", "type": "DRUG" }, { "name": "Etoposide (dose level 1)", "type": "DRUG" }, { "name": "Etoposide (dose level 2)", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Pemetrexed", "type": "DRUG" }, { "name": "External beam radiation (dose level 1)", "type": "RADIATION" }, { "name": "External beam radiation (dose level 2)", "type": "RADIATION" }, { "name": "External beam radiation (hyperfractionated)", "type": "RADIATION" }, { "name": "Cisplatin (dose level 1)", "type": "DRUG" }, { "name": "Cisplatin (dose level 2)", "type": "DRUG" }, { "name": "External beam radiation (standard)", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "110 Years", "sex": "ALL", "summary": "18 Years to 110 Years" }, "enrollment_count": 105, "start_date": "2018-05-02", "completion_date": "2025-01-08", "has_results": false, "last_update_posted_date": "2025-01-14", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 3, "location_summary": "Tucson, Arizona • Aurora, Colorado • Houston, Texas", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03509012" }, { "nct_id": "NCT02239328", "title": "A Study of Patient-reported Outcomes in Patients With Lung or Esophageal Cancer", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lung Cancer", "Esophageal Cancer" ], "interventions": [], "intervention_types": [], "sponsor": "University of Virginia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 182, "start_date": "2014-08", "completion_date": "2017-07-01", "has_results": true, "last_update_posted_date": "2018-10-26", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 1, "location_summary": "Charlottesville, Virginia", "locations": [ { "city": "Charlottesville", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02239328" }, { "nct_id": "NCT07423078", "title": "Window of Opportunity in Preserving Laryngeal Function Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)", "Locally Advanced Laryngeal Squamous Cell Carcinoma", "Hypopharyngeal Squamous Cell Carcinoma" ], "interventions": [ { "name": "Toripalimab", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Radiation Therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Matthew Spector", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 87, "start_date": "2026-04-06", "completion_date": "2031-04-30", "has_results": false, "last_update_posted_date": "2026-10-16", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07423078" }, { "nct_id": "NCT00459043", "title": "Docetaxel in Combination With Zactima (ZD6474) in Patients With Locally Advanced Squamous Cell Carcinoma of the the Head and Neck", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Squamous Cell Carcinoma of Head and Neck" ], "interventions": [ { "name": "ZD6474", "type": "DRUG" }, { "name": "Docetaxel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dana-Farber Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2007-03", "completion_date": "2012-02", "has_results": true, "last_update_posted_date": "2013-07-03", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 3, "location_summary": "Maywood, Illinois • Boston, Massachusetts", "locations": [ { "city": "Maywood", "state": "Illinois" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00459043" }, { "nct_id": "NCT04248582", "title": "Cryotherapy for Locally Advanced Esophageal Cancer", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Esophageal Cancer" ], "interventions": [ { "name": "Cryotherapy", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Hunter Holmes Mcguire Veteran Affairs Medical Center", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2020-02-11", "completion_date": "2027-03-01", "has_results": false, "last_update_posted_date": "2026-09-18", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04248582" }, { "nct_id": "NCT01465776", "title": "Freeze-Dried Black Raspberries in Treating Patients With Oral Squamous Cell Cancer Undergoing Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Squamous Cell Carcinoma of Mouth" ], "interventions": [ { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "preventative dietary intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Amit Agrawal", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 38, "start_date": "2005-01-10", "completion_date": "2010-02-16", "has_results": false, "last_update_posted_date": "2018-03-06", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01465776" }, { "nct_id": "NCT05399849", "title": "Mindfulness Intervention in Young Adults With a Concussion History", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Concussion, Brain", "Concussion Post Syndrome" ], "interventions": [ { "name": "Mindfulness Exercises and Meditations", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "18 Years to 30 Years" }, "enrollment_count": 15, "start_date": "2022-07-25", "completion_date": "2022-10-02", "has_results": false, "last_update_posted_date": "2022-10-14", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05399849" }, { "nct_id": "NCT00761397", "title": "Adherence to Swallowing Exercises in Head and Neck Cancer", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Head and Neck Cancer" ], "interventions": [ { "name": "Interview", "type": "BEHAVIORAL" }, { "name": "Phone Call", "type": "BEHAVIORAL" }, { "name": "Brochure", "type": "OTHER" }, { "name": "Questionnaire", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 485, "start_date": "2008-08-29", "completion_date": "2020-09-30", "has_results": false, "last_update_posted_date": "2020-01-13", "last_synced_at": "2026-10-20T04:18:27.229Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00761397" } ] }