{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Head+Injuries%2C+Multiple",
    "query": {
      "condition": "Head Injuries, Multiple"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 59,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Head+Injuries%2C+Multiple&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:10:05.057Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04677829",
      "title": "Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "PNT001",
          "type": "BIOLOGICAL"
        },
        {
          "name": "%5 dextrose for infusion",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Pinteon Therapeutics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 1,
      "start_date": "2021-03-29",
      "completion_date": "2021-04-12",
      "has_results": false,
      "last_update_posted_date": "2022-06-29",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04677829"
    },
    {
      "nct_id": "NCT03723434",
      "title": "Physiology of Interregional Connectivity in the Human Brain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Stroke",
        "Traumatic Brain Injury",
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Single-pulse transcranial magnetic stimulation (spTMS)",
          "type": "DEVICE"
        },
        {
          "name": "Paired associative stimulation (PAS)",
          "type": "DEVICE"
        },
        {
          "name": "Repetitive transcranial magnetic stimulation (rTMS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 76,
      "start_date": "2017-05-31",
      "completion_date": "2020-11",
      "has_results": false,
      "last_update_posted_date": "2018-10-29",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03723434"
    },
    {
      "nct_id": "NCT04423198",
      "title": "HEAD Injury Serum Markers and Multi-modalities for Assessing Response to Trauma",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mild Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Cognitive Assessment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Neurological Outcome Assessments",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Blood Draw",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "BRAINBox Solutions Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2020-12-31",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-08-04",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 11,
      "location_summary": "Kansas City, Kansas • Detroit, Michigan • Rochester, New York + 5 more",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04423198"
    },
    {
      "nct_id": "NCT00776048",
      "title": "Validation of an Obstacle Course Used in Patients With Muscle Tightness",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke",
        "Traumatic Brain Injury",
        "Multiple Sclerosis",
        "Spasticity",
        "Healthy Controls"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2007-01",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-06-24",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00776048"
    },
    {
      "nct_id": "NCT05183152",
      "title": "Non-invasive BCI-controlled Assistive Devices",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Motor Disorders",
        "Healthy",
        "Spinal Cord Injuries",
        "Muscular Diseases",
        "Motor Neuron Disease",
        "Stroke",
        "Traumatic Brain Injury",
        "Movement Disorders",
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "NMES Feedback",
          "type": "DEVICE"
        },
        {
          "name": "Visual Feedback",
          "type": "DEVICE"
        },
        {
          "name": "TESS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2021-06-16",
      "completion_date": "2028-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05183152"
    },
    {
      "nct_id": "NCT06078371",
      "title": "Opioid-Free Pain Treatment in Trauma Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Femoral Neck Fractures",
        "Intertrochanteric Fractures",
        "Femoral Shaft Fracture",
        "Distal Femur Fracture",
        "Patella Fracture",
        "Tibial Shaft Fracture with or Without Associated Fibula Fracture",
        "Ankle Fracture (bimalleolar Equivalent, Bimalleolar, or Trimalleolar)",
        "Tibial Pilon Fracture",
        "Talar Head, Neck, Body, or Process Fractures",
        "Calcaneus Fractures",
        "Lisfranc Injuries",
        "Isolated or Multiple Metatarsal Fractures",
        "Phalanx Fractures of the Foot, Single or Multiple",
        "Clavicle Fractures",
        "Proximal Humerus Fractures",
        "Humeral Shaft Fractures",
        "Distal Humerus Fractures (intra or Extra-articular)",
        "Olecranon Fractures",
        "Radial Head or Neck Fractures",
        "Elbow Fractures Involving a Combination of Fractures of the Radius and Uln",
        "Forearm Fractures (both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft)",
        "Distal Radius Fractures"
      ],
      "interventions": [
        {
          "name": "Opioid-free pain treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2023-11-01",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06078371"
    },
    {
      "nct_id": "NCT03806842",
      "title": "Easytech Reversed Shoulder System Clinical Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteo Arthritis Shoulders",
        "Avascular Necrosis of the Head of Humerus",
        "Rotator Cuff Tear"
      ],
      "interventions": [
        {
          "name": "Easytech group",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "FX Shoulder Solutions",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2018-11-28",
      "completion_date": "2024-12-28",
      "has_results": false,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 6,
      "location_summary": "Sun City West, Arizona • Menlo Park, California • Philadelphia, Pennsylvania + 3 more",
      "locations": [
        {
          "city": "Sun City West",
          "state": "Arizona"
        },
        {
          "city": "Menlo Park",
          "state": "California"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Wakefield",
          "state": "Rhode Island"
        },
        {
          "city": "Bedford",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03806842"
    },
    {
      "nct_id": "NCT04530955",
      "title": "Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Injuries, Spinal Cord",
        "CVA (Cerebrovascular Accident)",
        "Traumatic Brain Injury",
        "MS (Multiple Sclerosis)",
        "Muscle Spasticity",
        "Cerebral Palsy, Spastic"
      ],
      "interventions": [
        {
          "name": "Prometra II Programmable Pump - Flowonix Medical",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Culicchia Neurological Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 92,
      "start_date": "2020-09-24",
      "completion_date": "2023-06",
      "has_results": false,
      "last_update_posted_date": "2020-09-28",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 1,
      "location_summary": "Marrero, Louisiana",
      "locations": [
        {
          "city": "Marrero",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04530955"
    },
    {
      "nct_id": "NCT04806620",
      "title": "Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-Acute COVID-19 Syndrome",
        "ME/CFS",
        "Rheumatic Arthritis",
        "Juvenile Rheumatoid Arthritis (JRA)",
        "Psoriatic Arthritis (PsA)",
        "Ankylosing Spondylitis (AS)",
        "Autoimmune Encephalitis",
        "Celiac Disease",
        "Celiac Disease in Children",
        "Chronic Lyme Disease",
        "Post-treatment Lyme Disease Syndrome",
        "Crohn's Disease",
        "Dysautonomia",
        "Anorexia Nervosa",
        "Bulimia Nervosa",
        "ARFID",
        "Avoidant / Restrictive Food Intake Disorder",
        "Ehlers Danlos Syndrome",
        "Endometriosis",
        "Fibromyalgia (FM)",
        "Long COVID",
        "Lupus",
        "Migraines",
        "Mast Cell Activation Syndrome",
        "Multiple Sclerosis",
        "Myalgic Encephalomyelitis (ME)",
        "Myasthenia Gravis, Generalized",
        "Myasthenia Gravis in Children",
        "Narcolepsy",
        "Obsessive Compulsive Disorder (OCD)",
        "PANDAS",
        "Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)",
        "POTS - Postural Orthostatic Tachycardia Syndrome",
        "General Anxiety Disorder, Social Anxiety Disorder",
        "PTSD - Post Traumatic Stress Disorder",
        "Psoriasis",
        "Traumatic Brain Injury",
        "Tourette's Syndrome",
        "Inflammatory Bowel Disease (IBD)",
        "Autoimmune Diseases",
        "Neurological Diseases or Conditions",
        "Psychiatric Disorder",
        "Sjogren's Syndrome",
        "Ulcerative Colitis and Crohn's Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Brain Inflammation Collaborative",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2023-07-05",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-22",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 1,
      "location_summary": "Delafield, Wisconsin",
      "locations": [
        {
          "city": "Delafield",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04806620"
    },
    {
      "nct_id": "NCT04815967",
      "title": "Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Spasticity",
        "Cerebrovascular Accident",
        "Multiple Sclerosis",
        "Traumatic Brain Injury",
        "Cervical Spinal Cord Injury",
        "Cerebral Palsy"
      ],
      "interventions": [
        {
          "name": "Phase 2; Low Dose MYOBLOC",
          "type": "DRUG"
        },
        {
          "name": "Phase 2; High Dose MYOBLOC",
          "type": "DRUG"
        },
        {
          "name": "Phase 2; Placebo",
          "type": "DRUG"
        },
        {
          "name": "Phase 3; MYOBLOC",
          "type": "DRUG"
        },
        {
          "name": "Phase 3; Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Supernus Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 272,
      "start_date": "2021-11-16",
      "completion_date": "2024-07-01",
      "has_results": false,
      "last_update_posted_date": "2023-03-07",
      "last_synced_at": "2026-05-22T08:10:05.057Z",
      "location_count": 7,
      "location_summary": "Downey, California • Stamford, Connecticut • Bradenton, Florida + 4 more",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Boise",
          "state": "Idaho"
        },
        {
          "city": "Port Royal",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04815967"
    }
  ]
}