{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Headache+Disorders%2C+Secondary",
    "query": {
      "condition": "Headache Disorders, Secondary"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 91,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Headache+Disorders%2C+Secondary&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T01:54:21.566Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03806985",
      "title": "Effects of Psilocybin in Concussion Headache",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Post-Traumatic Headache"
      ],
      "interventions": [
        {
          "name": "Placebo oral capsule",
          "type": "DRUG"
        },
        {
          "name": "Low Dose Psilocybin",
          "type": "DRUG"
        },
        {
          "name": "High Dose Psilocybin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 12,
      "start_date": "2019-03-28",
      "completion_date": "2023-06-27",
      "has_results": false,
      "last_update_posted_date": "2023-10-12",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03806985"
    },
    {
      "nct_id": "NCT00122278",
      "title": "Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 205,
      "start_date": "2005-07",
      "completion_date": "2006-08",
      "has_results": true,
      "last_update_posted_date": "2018-11-13",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 3,
      "location_summary": "Manhattan, New York • New York, New York • The Bronx, New York",
      "locations": [
        {
          "city": "Manhattan",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00122278"
    },
    {
      "nct_id": "NCT04799015",
      "title": "Dexamethasone for Post Traumatic Headache",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-Traumatic Headache"
      ],
      "interventions": [
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Metoclopramide 10mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 162,
      "start_date": "2021-06-25",
      "completion_date": "2024-12-22",
      "has_results": true,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04799015"
    },
    {
      "nct_id": "NCT04356963",
      "title": "Adjunct VR Pain Management in Acute Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury",
        "Headaches Posttraumatic",
        "Trauma",
        "Pain, Acute"
      ],
      "interventions": [
        {
          "name": "Virtual Reality Session (VR Blu)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tablet-based Session (Tablet Blu)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Use of Virtual Reality Head Mounted Display without Content (VR Blank)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2020-09-05",
      "completion_date": "2022-04-30",
      "has_results": true,
      "last_update_posted_date": "2023-04-24",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04356963"
    },
    {
      "nct_id": "NCT04776304",
      "title": "Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Traumatic Headache",
        "PTSD",
        "TBI",
        "TBI (Traumatic Brain Injury)",
        "MTBI - Mild Traumatic Brain Injury",
        "Posttraumatic Stress Disorder",
        "Posttraumatic Stress Disorder, Delayed Onset",
        "Sleep Disturbance",
        "Nightmare",
        "Nightmares, REM-Sleep Type",
        "Headache",
        "Irritable Mood",
        "Anger",
        "Eating Disorders",
        "Combat and Operational Stress Reaction",
        "Combat Stress Disorders",
        "Military Operations",
        "Military Activity",
        "Military Family"
      ],
      "interventions": [
        {
          "name": "Art Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 2,
      "start_date": "2021-10-30",
      "completion_date": "2024-01-25",
      "has_results": false,
      "last_update_posted_date": "2024-11-06",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04776304"
    },
    {
      "nct_id": "NCT05620719",
      "title": "Multisite Advancement of Research on Chronic Posttraumatic Headache",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Headache"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Posttraumatic Headache",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment as Usual",
          "type": "OTHER"
        },
        {
          "name": "Telemedicine-based Cognitive Behavioral Therapy (TCBT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 525,
      "start_date": "2023-08-24",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-06-26",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Palo Alto, California • Honolulu, Hawaii + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05620719"
    },
    {
      "nct_id": "NCT02090998",
      "title": "Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Transformed Migraine",
        "Chronic Daily Headache"
      ],
      "interventions": [
        {
          "name": "SPG Block with 5% Lidocaine gel",
          "type": "PROCEDURE"
        },
        {
          "name": "Amitriptyline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2014-05",
      "completion_date": "2020-03-16",
      "has_results": true,
      "last_update_posted_date": "2026-06-23",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02090998"
    },
    {
      "nct_id": "NCT03560349",
      "title": "RCT of SPG Blocks for Post-dural Headache",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post-Dural Puncture Headache"
      ],
      "interventions": [
        {
          "name": "Lidocaine HCl Gel 2%",
          "type": "DRUG"
        },
        {
          "name": "placebo gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2018-07-01",
      "completion_date": "2019-01-01",
      "has_results": false,
      "last_update_posted_date": "2022-12-13",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03560349"
    },
    {
      "nct_id": "NCT05212844",
      "title": "McKenzie Method of Mechanical Diagnosis and Therapy for Management of Cervicogenic Headache: A Prospective Case Series",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cervicogenic Headache"
      ],
      "interventions": [
        {
          "name": "Musculoskeletal Physical Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Faith Regional Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "19 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-12-17",
      "completion_date": "2022-07-31",
      "has_results": false,
      "last_update_posted_date": "2022-01-28",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 1,
      "location_summary": "Norfolk, Nebraska",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05212844"
    },
    {
      "nct_id": "NCT05049057",
      "title": "Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Posttraumatic Headache",
        "Mild Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Erenumab 140 Mg/mL Subcutaneous Solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 404,
      "start_date": "2022-07-19",
      "completion_date": "2027-05-19",
      "has_results": false,
      "last_update_posted_date": "2024-02-22",
      "last_synced_at": "2026-07-23T01:54:21.566Z",
      "location_count": 4,
      "location_summary": "Fort Bragg, North Carolina • Pittsburgh, Pennsylvania • El Paso, Texas + 1 more",
      "locations": [
        {
          "city": "Fort Bragg",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "El Paso",
          "state": "Texas"
        },
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05049057"
    }
  ]
}