{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Headache+Migraine+Chronic&page=2", "query": { "condition": "Headache Migraine Chronic", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Headache+Migraine+Chronic&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-26T22:15:48.953Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02905227", "title": "A Study of the Pulmonary Safety and Pharmacokinetics of Zolmitriptan Inhalation Powder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Migraine" ], "interventions": [ { "name": "CVT-427 (zolmitriptan inhalation powder)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Acorda Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 60, "start_date": "2016-09", "completion_date": "2016-12", "has_results": false, "last_update_posted_date": "2018-02-14", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 3, "location_summary": "North Dartmouth, Massachusetts • Lincoln, Nebraska • Dallas, Texas", "locations": [ { "city": "North Dartmouth", "state": "Massachusetts" }, { "city": "Lincoln", "state": "Nebraska" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02905227" }, { "nct_id": "NCT00269581", "title": "Headstrong Intervention for Pediatric Headache", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Headaches" ], "interventions": [ { "name": "Educational CD-rom", "type": "OTHER" }, { "name": "Headstrong CD-rom", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Michael Rapoff, Ph.D.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "7 Years to 12 Years" }, "enrollment_count": 35, "start_date": "2004-08", "completion_date": "2010-05", "has_results": false, "last_update_posted_date": "2012-09-25", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 2, "location_summary": "Kansas City, Kansas • Kansas City, Missouri", "locations": [ { "city": "Kansas City", "state": "Kansas" }, { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00269581" }, { "nct_id": "NCT02720211", "title": "Spectacle Tints and Thin-Films for Migraine", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Headache Migraine Chronic" ], "interventions": [ { "name": "Gray tinted spectacle lenses", "type": "DEVICE" }, { "name": "Thin-Film spectacle lenses", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 10, "start_date": "2016-08", "completion_date": "2018-11-06", "has_results": true, "last_update_posted_date": "2022-11-29", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 4, "location_summary": "Phoenix, Arizona • Boston, Massachusetts • Great Neck, New York + 1 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Great Neck", "state": "New York" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02720211" }, { "nct_id": "NCT03231241", "title": "Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chronic Daily Headache", "Chronic Migraine" ], "interventions": [], "intervention_types": [], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 700, "start_date": "2014-12-12", "completion_date": "2026-09-01", "has_results": false, "last_update_posted_date": "2025-07-23", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03231241" }, { "nct_id": "NCT04031469", "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease", "overall_status": "SUSPENDED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Gut Microbiome", "Gastrointestinal Microbiome", "Autism", "Autism Spectrum Disorder", "Autism Spectrum Disorder High-Functioning", "Alzheimer Disease", "Alzheimer Dementia (AD)", "Alzheimer Dementia", "Alzheimer Disease (AD)", "Crohn", "Crohn Colitis", "Crohn Disease (CD)", "Crohn Disease Colon", "Myalgic Encephalomyelitis", "ME/CFS", "Myalgic Encephalomyelitis (ME)", "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", "Psoriasis", "Psoriasis Annularis", "Psoriasis Chronic", "Chronic Urinary Tract Infection", "Ulcerative Colitis (Disorder)", "Ulcerative Colitis (UC)", "Ulcerative Colitis Acute", "Ulcerative Colitis Chronic", "Multiple Sclerosis", "Multiple Sclerosis (MS) - Relapsing-remitting", "Multiple Sclerosis (MS) Primary Progressive", "Constipation Chronic Idiopathic", "Constipation", "Celiac", "Celiac Disease", "Celiac Sprue", "Lyme Arthritis", "Lyme Borreliosis, Nervous System", "Lyme Disease, Chronic", "Cholesterol", "Cholesterol Level, High", "Cancer", "Colon Cancer", "Amyotrophic Lateral Sclerosis (ALS)", "Amyotrophic Lateral Sclerosis", "Rheumatoid Arthritis (RA)", "Rheumatoid Arthritis - Rheumatism", "Chronic Fatigue Syndrome (CFS)", "PARKINSON DISEASE (Disorder)", "Parkinson Disease", "Parkinson Disease (PD)", "Depression", "Major Depressive Disorder (MDD)", "Depression Disorder", "Depression in Adults", "Anxiety", "Anxiety Disorder Generalized", "Obsessive Compulsive Disorder (OCD)", "Obsessive Compulsive Disorder OCD", "Obsessive - Compulsive Disorder", "Bipolar", "Bipolar 1 Disorder", "Bipolar Disorder (BD)", "Bipolar Disorder I and II", "Bipolar and Related Disorders", "Migraine", "Migraine Disorder", "Diabetes (DM)", "Diabetes", "Lupus", "Lupus Erythematosus", "Epidermolysis Bullosa (EB)", "Mesothelioma", "Mesothelioma Malignant", "IBS (Irritable Bowel Syndrome)", "Irritable Bowel", "IBS - Irritable Bowel Syndrome", "Irritable Bowel Syndrome (IBS)", "Eczema", "Eczema Atopic Dermatitis", "Acne", "Myasthaenia Gravis", "Gout" ], "interventions": [ { "name": "There is no intervention in this study", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "ProgenaBiome", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 1000, "start_date": "2019-07-11", "completion_date": "2030-12-10", "has_results": false, "last_update_posted_date": "2025-07-31", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 1, "location_summary": "Ventura, California", "locations": [ { "city": "Ventura", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04031469" }, { "nct_id": "NCT07487701", "title": "Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Migraine", "Chronic Migraine Headache" ], "interventions": [ { "name": "Nerivio REN device", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Theranica", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": null, "sex": "ALL", "summary": "8 Years and older" }, "enrollment_count": 150, "start_date": "2026-02-20", "completion_date": "2026-04-15", "has_results": false, "last_update_posted_date": "2026-03-23", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 1, "location_summary": "Bridgewater, New Jersey", "locations": [ { "city": "Bridgewater", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT07487701" }, { "nct_id": "NCT05679908", "title": "A Study to Evaluate the Efficacy and Safety of TNX-1900 in Patients With Chronic Migraine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Migraine", "Chronic Migraine, Headache", "Chronic Migraine Without Aura", "Aura Migraine" ], "interventions": [ { "name": "TNX-1900", "type": "DRUG" }, { "name": "Placebo Nasal Spray", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tonix Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 88, "start_date": "2022-12-06", "completion_date": "2023-10-23", "has_results": true, "last_update_posted_date": "2025-02-25", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 26, "location_summary": "Little Rock, Arkansas • Lemon Grove, California • Oceanside, California + 23 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Lemon Grove", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "Temecula", "state": "California" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05679908" }, { "nct_id": "NCT05893914", "title": "Intramuscular Electrical Stimulation for the Treatment of Trigger Points in Patients With Migraine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Migraine" ], "interventions": [ { "name": "Dry Needling and intramuscular electrical stimulation to trigger points", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Thomas W. Perreault, PT", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 4, "start_date": "2023-08-04", "completion_date": "2024-10-07", "has_results": false, "last_update_posted_date": "2025-05-08", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 1, "location_summary": "Dover, New Hampshire", "locations": [ { "city": "Dover", "state": "New Hampshire" } ], "official_url": "https://clinicaltrials.gov/study/NCT05893914" }, { "nct_id": "NCT05730556", "title": "A Study of Remote Electrical Neuromodulation for Acute Procedural Pain", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Migraine" ], "interventions": [ { "name": "Nerivio ®", "type": "DEVICE" }, { "name": "Sham", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 80, "start_date": "2023-02-13", "completion_date": "2024-09-09", "has_results": true, "last_update_posted_date": "2025-10-27", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 1, "location_summary": "Scottsdale, Arizona", "locations": [ { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT05730556" }, { "nct_id": "NCT03526874", "title": "Occipital Blocks for Acute Migraine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Migraine, Headache", "Episodic Migraine" ], "interventions": [ { "name": "Lidocaine 4% Topical Application Cream [LMX 4]", "type": "DRUG" }, { "name": "Lidocaine Hydrochloride 2 mg/mL Injectable Solution", "type": "DRUG" }, { "name": "Normal Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "7 Years to 21 Years" }, "enrollment_count": 63, "start_date": "2019-04-03", "completion_date": "2023-03-10", "has_results": true, "last_update_posted_date": "2025-04-17", "last_synced_at": "2026-06-26T22:15:48.953Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03526874" } ] }