{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Healthy+Smokers",
    "query": {
      "condition": "Healthy Smokers"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Healthy+Smokers&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T05:12:25.521Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04019626",
      "title": "A Study to Assess Tobacco-related Biomarkers of Exposure in Smokers Using myBlu E-cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Continue-smoking",
          "type": "OTHER"
        },
        {
          "name": "myblu Tobacco 2.5%",
          "type": "OTHER"
        },
        {
          "name": "myblu Tobacco 4.0%",
          "type": "OTHER"
        },
        {
          "name": "myblu Honeymoon 2.5%",
          "type": "OTHER"
        },
        {
          "name": "myblu Honeymoon 4.0%",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5%",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fontem Ventures BV",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 240,
      "start_date": "2019-03-01",
      "completion_date": "2020-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-06-30",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04019626"
    },
    {
      "nct_id": "NCT01375933",
      "title": "A Comparability Study of the Phase 3 Lot and a Single Commercial Lot of NicVAX in Healthy Adult Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "NicVAX Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Nabi Biopharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 260,
      "start_date": "2011-05",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2012-05-14",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 6,
      "location_summary": "Huntsville, Alabama • San Diego, California • Melbourne, Florida + 3 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Melbourne",
          "state": "Florida"
        },
        {
          "city": "Peoria",
          "state": "Illinois"
        },
        {
          "city": "South Bend",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01375933"
    },
    {
      "nct_id": "NCT02906995",
      "title": "Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tobacco Use Disorder",
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Sublingual tablet 4 mg versus Nicorette Lozenge 4mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Friends Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 24,
      "start_date": "2017-05-25",
      "completion_date": "2017-11-27",
      "has_results": false,
      "last_update_posted_date": "2017-12-04",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "Raleigh, North Carolina",
      "locations": [
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02906995"
    },
    {
      "nct_id": "NCT04429932",
      "title": "A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Myblu flavor A_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor B_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor C_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor D_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor E_1.2",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor F_1.2",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor G_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor H_2.4",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fontem US LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 39,
      "start_date": "2019-12-01",
      "completion_date": "2020-01-31",
      "has_results": true,
      "last_update_posted_date": "2021-06-07",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04429932"
    },
    {
      "nct_id": "NCT00414960",
      "title": "A Trial of Placebo Versus Enzastaurin for Lung Cancer Prevention in Former Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "Enzastaurin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eli Lilly and Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2007-12",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2020-09-21",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00414960"
    },
    {
      "nct_id": "NCT01974063",
      "title": "Alternate Nicotine Delivery Systems and Airway Epithelial Biology",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Smoking",
        "Smoking Cessation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2013-03",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2018-05-03",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01974063"
    },
    {
      "nct_id": "NCT01632384",
      "title": "The Effects of Smoking Withdrawal On Resting State Functional Connectivity",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Abstain from smoking for 24 hours",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 0,
      "start_date": "2012-02",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2017-01-31",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01632384"
    },
    {
      "nct_id": "NCT00565214",
      "title": "Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease (COPD)"
      ],
      "interventions": [
        {
          "name": "Group 1",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Group 2",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 46,
      "start_date": "2007-09",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2017-05-25",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00565214"
    },
    {
      "nct_id": "NCT02585791",
      "title": "Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Lifetime Non-smokers"
      ],
      "interventions": [
        {
          "name": "Propylene Glycol",
          "type": "OTHER"
        },
        {
          "name": "vegetable glycerin",
          "type": "OTHER"
        },
        {
          "name": "PG+VG",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-02-22",
      "completion_date": "2019-12-11",
      "has_results": false,
      "last_update_posted_date": "2020-01-14",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02585791"
    },
    {
      "nct_id": "NCT02575885",
      "title": "Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoker",
        "Current Smoker",
        "Healthy Subject"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Pharmacological Study",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Roswell Park Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 36,
      "start_date": "2016-03-16",
      "completion_date": "2018-06-06",
      "has_results": false,
      "last_update_posted_date": "2018-06-12",
      "last_synced_at": "2026-07-22T05:12:25.521Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02575885"
    }
  ]
}