{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hearing+Loss%2C+Profound",
    "query": {
      "condition": "Hearing Loss, Profound"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hearing+Loss%2C+Profound&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T18:49:32.300Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01616576",
      "title": "Evaluation of a HiRes™ Optima Sound Processing Strategy for the HiResolution™ Bionic Ear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe to Profound Hearing Loss",
        "in Adult Users of Advanced Bionics HiResolution™ Bionic Ear System"
      ],
      "interventions": [
        {
          "name": "Control first, then Experimental",
          "type": "DEVICE"
        },
        {
          "name": "Experimental first, then Control",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Advanced Bionics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2012-05",
      "completion_date": "2012-09",
      "has_results": true,
      "last_update_posted_date": "2020-07-22",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 5,
      "location_summary": "Los Angeles, California • Tampa, Florida • Urbana, Illinois + 2 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Urbana",
          "state": "Illinois"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01616576"
    },
    {
      "nct_id": "NCT00678899",
      "title": "Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sensorineural Hearing Loss"
      ],
      "interventions": [
        {
          "name": "Nucleus Hybrid L24",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cochlear",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2008-04",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2015-07-15",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00678899"
    },
    {
      "nct_id": "NCT02203305",
      "title": "Cochlear Implantation in Cases of Single-Sided Deafness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Unilateral Moderate to Profound Hearing Loss",
        "Asymmetric Hearing Loss",
        "Single-Sided Deafness (SSD)"
      ],
      "interventions": [
        {
          "name": "Cochlear Implant",
          "type": "DEVICE"
        },
        {
          "name": "Control Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2014-10",
      "completion_date": "2021-09-16",
      "has_results": true,
      "last_update_posted_date": "2022-07-25",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02203305"
    },
    {
      "nct_id": "NCT02132130",
      "title": "Safety, Tolerability and Efficacy for CGF166 in Patients With Unilateral or Bilateral Severe-to-profound Hearing Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Unilateral Severe to Profound Hearing Loss OR Bilateral Severe to Profound Hearing Loss"
      ],
      "interventions": [
        {
          "name": "CGF166",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 22,
      "start_date": "2014-06-23",
      "completion_date": "2019-12-09",
      "has_results": true,
      "last_update_posted_date": "2021-10-08",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 4,
      "location_summary": "Kansas City, Kansas • Baltimore, Maryland • New York, New York + 1 more",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02132130"
    },
    {
      "nct_id": "NCT02589912",
      "title": "Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients",
      "overall_status": "NO_LONGER_AVAILABLE",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Neurofibromatosis Type 2",
        "Severe Profound Sensorineural Hearing Loss"
      ],
      "interventions": [
        {
          "name": "Nucleus Profile ABI541 Auditory Brainstem Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts Eye and Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "12 Years to 80 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2019-12-06",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02589912"
    },
    {
      "nct_id": "NCT01904448",
      "title": "Auditory Brainstem Implantation in Young Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Developmental Cochlear Nerve Deficiency",
        "Acquired Cochlear Nerve Deficiency",
        "Cochlear Aplasia",
        "Post-meningitis Cochlear Ossification",
        "Cochlear Malformation"
      ],
      "interventions": [
        {
          "name": "Auditory Brainstem Implantation in Children",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "18 Months to 17 Years"
      },
      "enrollment_count": 5,
      "start_date": "2012-09",
      "completion_date": "2017-10-01",
      "has_results": true,
      "last_update_posted_date": "2018-07-05",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01904448"
    },
    {
      "nct_id": "NCT01975571",
      "title": "Hybrid Cochlear Implants in Severe to Profound Adults, Children, and Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hearing Loss, High-Frequency"
      ],
      "interventions": [
        {
          "name": "Cochlear® Nucleus™ Hybrid L24",
          "type": "DEVICE"
        },
        {
          "name": "Cochlear® Nucleus™ Hybrid S12",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bruce J Gantz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2011-07",
      "completion_date": "2018-09-08",
      "has_results": true,
      "last_update_posted_date": "2022-06-08",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01975571"
    },
    {
      "nct_id": "NCT02102256",
      "title": "A Safety Study of the Auditory Brainstem Implant for Pediatric Profoundly Deaf Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Profound Bilateral Deafness Due to",
        "Bilateral Cochlear Aplasia",
        "Bilateral Cochlear Nerve Deficiency",
        "Bilateral Cochlear Ossification Secondary to Meningitis"
      ],
      "interventions": [
        {
          "name": "Auditory Brainstem Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Laurie Eisenberg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "2 Years to 6 Years"
      },
      "enrollment_count": 10,
      "start_date": "2014-03",
      "completion_date": "2021-04-06",
      "has_results": true,
      "last_update_posted_date": "2025-09-15",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02102256"
    },
    {
      "nct_id": "NCT06699797",
      "title": "Pivotal Clinical Trial Evaluating the Safety and Efficacy of the Fully Implanted Acclaim Cochlear Implant",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sensori-Neural Deafness",
        "Sensorineural Hearing Loss",
        "Sensorineural Hearing Loss (Disorder)",
        "Sensorineural Hearing Loss, Bilateral",
        "Sensorineural Hearing Loss, Profound",
        "Sensorineural Hearing Loss, Severe"
      ],
      "interventions": [
        {
          "name": "Acclaim Cochlear Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Envoy Medical Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2025-02-06",
      "completion_date": "2028-04",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 7,
      "location_summary": "Tucson, Arizona • Seal Beach, California • Gainesville, Florida + 4 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Seal Beach",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06699797"
    },
    {
      "nct_id": "NCT03261726",
      "title": "Maintaining Cochlear Patency After VIIIth Nerve Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acoustic Neuroma",
        "Labyrinthitis Ossificans",
        "Profound Hearing Impairment"
      ],
      "interventions": [
        {
          "name": "MedEl Test Electrode Placer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2017-08-04",
      "completion_date": "2021-03-04",
      "has_results": false,
      "last_update_posted_date": "2025-12-19",
      "last_synced_at": "2026-07-22T18:49:32.300Z",
      "location_count": 1,
      "location_summary": "Farmington Hills, Michigan",
      "locations": [
        {
          "city": "Farmington Hills",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03261726"
    }
  ]
}