{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Disease+Chronic&page=2",
    "query": {
      "condition": "Heart Disease Chronic",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Disease+Chronic&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T19:26:10.911Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01205776",
      "title": "EXCEL Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Coronary Occlusion",
        "Unprotected Left Main Coronary Artery Disease",
        "Stent Thrombosis",
        "Vascular Disease",
        "Myocardial Ischemia",
        "Coronary Artery Stenosis",
        "Coronary Disease",
        "Coronary Artery Disease",
        "Coronary Restenosis"
      ],
      "interventions": [
        {
          "name": "Percutaneous Coronary Intervention",
          "type": "DEVICE"
        },
        {
          "name": "CABG",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1905,
      "start_date": "2010-09-29",
      "completion_date": "2019-06-28",
      "has_results": true,
      "last_update_posted_date": "2020-04-07",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 1,
      "location_summary": "Santa Clara, California",
      "locations": [
        {
          "city": "Santa Clara",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01205776"
    },
    {
      "nct_id": "NCT01817686",
      "title": "Study of Default Options in Advance Directives",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD",
        "Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy",
        "Idiopathic Pulmonary Fibrosis",
        "Other Interstitial Lung Disease Without Curative Therapy",
        "Congestive Heart Failure",
        "NYHA Class IV or NYHA Class III Plus 1 Hospitalization in the Past Year",
        "Malignancy",
        "Any Stage 3B or 4 Solid Tumor"
      ],
      "interventions": [
        {
          "name": "Comfort Default AD forms",
          "type": "OTHER"
        },
        {
          "name": "Life Extension Default AD forms",
          "type": "OTHER"
        },
        {
          "name": "Standard Default AD forms",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Corporal Michael J. Crescenz VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2013-03",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-30",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01817686"
    },
    {
      "nct_id": "NCT01112579",
      "title": "Determining the Feasibility of Spinal Cord Neuromodulation for the Treatment of Chronic Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Medtronic PrimeADVANCED Neurostimulator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiac Rhythm and Heart Failure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 81,
      "start_date": "2010-04",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2015-10-29",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 6,
      "location_summary": "Miami, Florida • Indianapolis, Indiana • Allentown, Pennsylvania + 3 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Allentown",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01112579"
    },
    {
      "nct_id": "NCT02970669",
      "title": "Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure, Reduced Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "sacubitril/valsartan (LCZ696)",
          "type": "DRUG"
        },
        {
          "name": "enalapril",
          "type": "DRUG"
        },
        {
          "name": "matching placebo sacubitril/valsartan (LCZ696)",
          "type": "DRUG"
        },
        {
          "name": "matching placebo enalapril",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 140,
      "start_date": "2016-12-16",
      "completion_date": "2018-03-19",
      "has_results": true,
      "last_update_posted_date": "2021-10-07",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 23,
      "location_summary": "Fort Payne, Alabama • Beverly Hills, California • Stockton, California + 20 more",
      "locations": [
        {
          "city": "Fort Payne",
          "state": "Alabama"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Stockton",
          "state": "California"
        },
        {
          "city": "West Hills",
          "state": "California"
        },
        {
          "city": "Doral",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02970669"
    },
    {
      "nct_id": "NCT00009646",
      "title": "Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Very Low Birth Weight",
        "Infant, Premature",
        "Ductus Arteriosus, Patent"
      ],
      "interventions": [
        {
          "name": "Indomethacin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Hours",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "2 Hours to 6 Hours"
      },
      "enrollment_count": 1202,
      "start_date": "1993-11",
      "completion_date": "2001-03",
      "has_results": false,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 9,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00009646"
    },
    {
      "nct_id": "NCT01206062",
      "title": "Systolic Blood Pressure Intervention Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Intensive control of SBP",
          "type": "DRUG"
        },
        {
          "name": "Standard control of SBP",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 9361,
      "start_date": "2010-10",
      "completion_date": "2019-03",
      "has_results": true,
      "last_update_posted_date": "2021-01-08",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01206062"
    },
    {
      "nct_id": "NCT01763996",
      "title": "The Influence of Febuxostat on Coronary Artery Endothelial Dysfunction in Participants With Chronic Stable Angina",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Febuxostat",
          "type": "DRUG"
        },
        {
          "name": "Febuxostat placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 30,
      "start_date": "2013-05",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2016-04-13",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01763996"
    },
    {
      "nct_id": "NCT03519347",
      "title": "Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes/Ultrafiltration, Study A",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Potassium Removal Maximization",
          "type": "OTHER"
        },
        {
          "name": "Potassium Gradient Minimization",
          "type": "OTHER"
        },
        {
          "name": "Alkalosis Avoidance",
          "type": "OTHER"
        },
        {
          "name": "Acidosis avoidance",
          "type": "OTHER"
        },
        {
          "name": "Point of Care Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Cardiac Monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 19,
      "start_date": "2018-11-30",
      "completion_date": "2022-10-14",
      "has_results": true,
      "last_update_posted_date": "2023-08-15",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03519347"
    },
    {
      "nct_id": "NCT00409916",
      "title": "PREVENT-HF: Prevention of Heart Failure Events With Impedance Cardiography Testing",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure, Congestive"
      ],
      "interventions": [
        {
          "name": "BioZ Dx",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CardioDynamics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2007-01",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2009-06-03",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 3,
      "location_summary": "Sacramento, California • San Diego, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00409916"
    },
    {
      "nct_id": "NCT02884206",
      "title": "Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Heart Failure (CHF)"
      ],
      "interventions": [
        {
          "name": "LCZ696",
          "type": "DRUG"
        },
        {
          "name": "Valsartan",
          "type": "DRUG"
        },
        {
          "name": "Placebo of LCZ696",
          "type": "DRUG"
        },
        {
          "name": "Placebo of Valsartan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 592,
      "start_date": "2016-11-23",
      "completion_date": "2022-05-16",
      "has_results": true,
      "last_update_posted_date": "2024-08-06",
      "last_synced_at": "2026-06-26T19:26:10.911Z",
      "location_count": 52,
      "location_summary": "Andalusia, Alabama • Glendale, Arizona • Mesa, Arizona + 45 more",
      "locations": [
        {
          "city": "Andalusia",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sun City West",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02884206"
    }
  ]
}