{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Diseases+in+Pregnancy&page=3",
    "query": {
      "condition": "Heart Diseases in Pregnancy",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 307,
    "total_pages": 31,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Diseases+in+Pregnancy&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Diseases+in+Pregnancy&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T14:16:26.515Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03701074",
      "title": "Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Patent Ductus Arteriosus",
        "Preterm Infant",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Ibuprofen and acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen and placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of South Alabama",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Days",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "5 Days to 21 Days"
      },
      "enrollment_count": 1,
      "start_date": "2018-12-15",
      "completion_date": "2020-12-02",
      "has_results": true,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 1,
      "location_summary": "Mobile, Alabama",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03701074"
    },
    {
      "nct_id": "NCT00870220",
      "title": "Initiating Transdermal Estradiol Therapy in Turner's Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Turner's Syndrome"
      ],
      "interventions": [
        {
          "name": "Norditropin, Menostar 14mcg patch, Vivelle dot 25mcg patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "138 Months",
        "maximum_age": "13 Years",
        "sex": "FEMALE",
        "summary": "138 Months to 13 Years · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2009-04",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2014-03-11",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00870220"
    },
    {
      "nct_id": "NCT02791880",
      "title": "Acute Kidney Injury Genomics and Biomarkers in TAVR Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Kidney Injury",
        "Renal Insufficiency, Chronic",
        "Heart Failure",
        "Myocardial Infarction",
        "Arrhythmias, Cardiac",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Transcatheter Aortic Valve Replacement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2016-10-25",
      "completion_date": "2031-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-29",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 3,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02791880"
    },
    {
      "nct_id": "NCT03133663",
      "title": "Heart Rate Evaluation and Resuscitation Trial in Preterm Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Resuscitation",
        "Infant, Premature"
      ],
      "interventions": [
        {
          "name": "Electrocardiogram group",
          "type": "OTHER"
        },
        {
          "name": "Pulse oximeter and auscultation group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Hour",
        "sex": "ALL",
        "summary": "Up to 1 Hour"
      },
      "enrollment_count": 51,
      "start_date": "2017-06-13",
      "completion_date": "2018-03-23",
      "has_results": false,
      "last_update_posted_date": "2018-12-21",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03133663"
    },
    {
      "nct_id": "NCT06995144",
      "title": "Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure",
        "Edema",
        "Pulmonary Congestion",
        "Fluid Overload"
      ],
      "interventions": [
        {
          "name": "Extended Release Torsemide Tablets",
          "type": "DRUG"
        },
        {
          "name": "Immedate Release Torsemide Tablets",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sarfez Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-05",
      "completion_date": "2026-09-16",
      "has_results": false,
      "last_update_posted_date": "2026-09-28",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06995144"
    },
    {
      "nct_id": "NCT03551600",
      "title": "Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infant, Premature",
        "Congenital Heart Disease",
        "Patent Ductus Arteriosus",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Near-infrared spectroscopy (NIRS)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Days",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "12 Days to 6 Months"
      },
      "enrollment_count": 64,
      "start_date": "2015-10",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-04-04",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 3,
      "location_summary": "Murray, Utah • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03551600"
    },
    {
      "nct_id": "NCT00709865",
      "title": "Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Renal Insufficiency",
        "Congestive Heart Failure"
      ],
      "interventions": [
        {
          "name": "tonapofylline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Biogen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 420,
      "start_date": "2008-07-31",
      "completion_date": "2009-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-09-11",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 68,
      "location_summary": "Huntsville, Alabama • Mobile, Alabama • Fort Smith, Arkansas + 64 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Fort Smith",
          "state": "Arkansas"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00709865"
    },
    {
      "nct_id": "NCT04144660",
      "title": "\"Treatment Use of ECMO In Pregnancy or Peripartum Patient.\"",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiogenic Shock",
        "Peripartum Cardiomyopathy",
        "Complication, Pregnancy"
      ],
      "interventions": [
        {
          "name": "Extracorporeal Membrane Oxygenation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sarah Thordsen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 5,
      "start_date": "2019-10-28",
      "completion_date": "2020-03-31",
      "has_results": false,
      "last_update_posted_date": "2020-11-23",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04144660"
    },
    {
      "nct_id": "NCT01085955",
      "title": "Investigation in Pregnancy Associate Cardiomyopathy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiomyopathy",
        "Pregnancy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "16 Years and older · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2009-10",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2016-01-15",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 28,
      "location_summary": "Los Angeles, California • Miami, Florida • Augusta, Georgia + 23 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01085955"
    },
    {
      "nct_id": "NCT03670732",
      "title": "CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Respiratory Distress Syndrome",
        "Apnea of Prematurity"
      ],
      "interventions": [
        {
          "name": "continuous positive airway pressure",
          "type": "OTHER"
        },
        {
          "name": "nasal intermittent positive pressure ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Women and Infants Hospital of Rhode Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 52,
      "start_date": "2017-09-30",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-30",
      "last_synced_at": "2026-10-09T14:16:26.515Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03670732"
    }
  ]
}