{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Rate+Variability&page=2",
    "query": {
      "condition": "Heart Rate Variability",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Rate+Variability&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:23:56.305Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05425290",
      "title": "Emotion Regulation Training to Reduce Cardiovascular Disease Risk Among Depressed Young Adults in Southern Mississippi",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Cardiovascular Diseases",
        "Inflammation",
        "Blood Pressure",
        "Heart Rate Variability"
      ],
      "interventions": [
        {
          "name": "Single-session emotion regulation training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern Mississippi",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "18 Years to 29 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-08-25",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-05-14",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Hattiesburg, Mississippi",
      "locations": [
        {
          "city": "Hattiesburg",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05425290"
    },
    {
      "nct_id": "NCT04393623",
      "title": "Stress, Emotion Regulation, and Alcohol in Women Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use Disorder",
        "Post Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Cognitive Reappraisal",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 81,
      "start_date": "2020-11-01",
      "completion_date": "2024-09-30",
      "has_results": true,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Leeds, Massachusetts",
      "locations": [
        {
          "city": "Leeds",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04393623"
    },
    {
      "nct_id": "NCT00215228",
      "title": "Effects of Duloxetine vs. Escitalopram on Heart Rate Variability in Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "duloxetine vs. escitalopram",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "20 Years to 60 Years"
      },
      "enrollment_count": 26,
      "start_date": "2005-07",
      "completion_date": "2007-08",
      "has_results": false,
      "last_update_posted_date": "2014-07-21",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00215228"
    },
    {
      "nct_id": "NCT03280589",
      "title": "Pranayama Practice on the Autonomic Nervous System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pranayama Effect on Autonomic Nervous System",
        "Respiration Variability Effect on Nervous System"
      ],
      "interventions": [
        {
          "name": "Sheetali/Sheekari Pranayama",
          "type": "OTHER"
        },
        {
          "name": "Sitting Quietly",
          "type": "OTHER"
        },
        {
          "name": "Deep breathing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "National University of Natural Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "25 Years to 55 Years"
      },
      "enrollment_count": 25,
      "start_date": "2017-08-15",
      "completion_date": "2021-07-21",
      "has_results": false,
      "last_update_posted_date": "2023-03-24",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03280589"
    },
    {
      "nct_id": "NCT07220421",
      "title": "Foundational Programs to Combat Clinician Stress",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burnout, Professional",
        "Stress, Psychological",
        "Stress, Physiological",
        "Psychological Well-Being",
        "Mind-Body Therapies",
        "Work Related Stress"
      ],
      "interventions": [
        {
          "name": "Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Education Program (HEP)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Lancaster General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "25 Years to 70 Years"
      },
      "enrollment_count": 180,
      "start_date": "2025-09-15",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2025-10-23",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 6,
      "location_summary": "Boston, Massachusetts • Plainsboro, New Jersey • Lancaster, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Plainsboro",
          "state": "New Jersey"
        },
        {
          "city": "Lancaster",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07220421"
    },
    {
      "nct_id": "NCT01359683",
      "title": "Heart Rate Variability Changes During Cardiac Surgery And The Incidence Of Post-Operative Cardiac Arrhythmias",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Arrhythmia"
      ],
      "interventions": [
        {
          "name": "Dataq Instruments DI-158",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Drexel University College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2007-09",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2013-06-14",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01359683"
    },
    {
      "nct_id": "NCT03838627",
      "title": "Feasibility and Agreement of Remote Evaluation of Resting Heart Rate and Heart Rate Variability in Survivors of Hodgkin Lymphoma Treated With Chest Radiation (PILOT STUDY-SURVIVOR)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hodgkin Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2019-02-05",
      "completion_date": "2023-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-12",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03838627"
    },
    {
      "nct_id": "NCT06455527",
      "title": "Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "Active Transcranial Direct Current Stimulation (tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Transcranial Direct Current Stimulation (tDCS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-01-02",
      "completion_date": "2027-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-28",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06455527"
    },
    {
      "nct_id": "NCT04910997",
      "title": "Heart Rate Variability-Guided Exercise Training in Type 2 Diabetes",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Diabetes Mellitus, Type 2",
        "Type 2 Diabetes Mellitus in Obese"
      ],
      "interventions": [
        {
          "name": "Aerobic exercise training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-06-01",
      "completion_date": "2022-05-03",
      "has_results": false,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04910997"
    },
    {
      "nct_id": "NCT00195975",
      "title": "Heart Rate Variability in Children With a Functional Gastrointestinal Disorder",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Abdominal Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 44,
      "start_date": "2005-06",
      "completion_date": "2009-03",
      "has_results": false,
      "last_update_posted_date": "2011-06-28",
      "last_synced_at": "2026-05-22T09:23:56.305Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00195975"
    }
  ]
}