{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Rate+Variability+%28HRV%29&page=2",
    "query": {
      "condition": "Heart Rate Variability (HRV)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heart+Rate+Variability+%28HRV%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:51:52.674Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03458910",
      "title": "Heart Rate Variability and Emotion Regulation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Rate Variability"
      ],
      "interventions": [
        {
          "name": "HRV training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 193,
      "start_date": "2018-02-14",
      "completion_date": "2020-05-05",
      "has_results": true,
      "last_update_posted_date": "2025-07-23",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03458910"
    },
    {
      "nct_id": "NCT04105998",
      "title": "Effects of Intramuscular (IM) Oxytocin on Pupil Diameter and Heart Rate Variability (HRV)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Pain Due to Injury"
      ],
      "interventions": [
        {
          "name": "Oxytocin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "66 Years",
        "sex": "ALL",
        "summary": "18 Years to 66 Years"
      },
      "enrollment_count": 22,
      "start_date": "2019-10-24",
      "completion_date": "2021-11-01",
      "has_results": true,
      "last_update_posted_date": "2022-11-10",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04105998"
    },
    {
      "nct_id": "NCT01184755",
      "title": "RCT of Effects of Device-guided Breathing on Ambulatory BP",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Relaxation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "RESPeRate",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 253,
      "start_date": "2008-05",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2017-05-16",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 2,
      "location_summary": "New Brunswick, New Jersey • New York, New York",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01184755"
    },
    {
      "nct_id": "NCT06365723",
      "title": "Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PreDiabetes",
        "Heart Rate Variability (HRV)",
        "Stress and Anxiety",
        "Stress Biomarkers"
      ],
      "interventions": [
        {
          "name": "Nature-based Walking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Built-environment/Commercial Walking",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "25 Years to 64 Years"
      },
      "enrollment_count": 216,
      "start_date": "2024-06-06",
      "completion_date": "2027-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-22",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 3,
      "location_summary": "Lake Forest, Illinois • Winfield, Illinois • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Lake Forest",
          "state": "Illinois"
        },
        {
          "city": "Winfield",
          "state": "Illinois"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06365723"
    },
    {
      "nct_id": "NCT07599475",
      "title": "Mobile Dual-Task Brain and Balance Intervention for Concussion Recovery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Traumatic Brain Injury (mTBI)",
        "Sports-related Concussion",
        "Heart Rate Variability (HRV)",
        "Walking",
        "Oculomotor",
        "Saliva",
        "Exosomal microRNA",
        "Cognitive Function"
      ],
      "interventions": [
        {
          "name": "Home-Based Mobile Dual-Task Intervention (BraW-Day™)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Hyunhwa Lee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-05-15",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07599475"
    },
    {
      "nct_id": "NCT02193373",
      "title": "Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteopathic Manual Manipulation of Neurovascular Regulation"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manual Medicine",
          "type": "OTHER"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 126,
      "start_date": "2014-06",
      "completion_date": "2018-05",
      "has_results": false,
      "last_update_posted_date": "2019-07-05",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02193373"
    },
    {
      "nct_id": "NCT07361731",
      "title": "Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autonomic Nervous System Imbalance",
        "Heart Rate Variability (HRV)",
        "Opioid Use Disorder",
        "Breathing Techniques",
        "Opioid Craving",
        "Recovery",
        "Emotional Regulation",
        "Positive and Negative Affect",
        "Stress",
        "Biofeedback"
      ],
      "interventions": [
        {
          "name": "Heart rate variability biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2025-12-01",
      "completion_date": "2026-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07361731"
    },
    {
      "nct_id": "NCT07015047",
      "title": "Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Recovery of Function (G11.427.698.620)",
        "Athletic Performance",
        "Heart Rate Variability (HRV)"
      ],
      "interventions": [
        {
          "name": "Magnesium L-Threonate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-10-01",
      "completion_date": "2026-07-15",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07015047"
    },
    {
      "nct_id": "NCT03692624",
      "title": "Use of Heart Rate Variability (HRV) Biofeedback for Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2015-05-10",
      "completion_date": "2020-02-07",
      "has_results": false,
      "last_update_posted_date": "2020-03-06",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03692624"
    },
    {
      "nct_id": "NCT00735618",
      "title": "Relaxation and Heart Rate Variability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Guided Relaxation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2008-06",
      "completion_date": "2008-09",
      "has_results": true,
      "last_update_posted_date": "2011-12-19",
      "last_synced_at": "2026-05-22T04:51:52.674Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00735618"
    }
  ]
}