{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heartburn",
    "query": {
      "condition": "Heartburn"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 91,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Heartburn&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:10:35.843Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00171470",
      "title": "The Role of Tegaserod Therapy in the Management of Dyspeptic Symptoms in Female Patients on Proton Pump Inhibitors for the Treatment of Heartburn.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dyspepsia"
      ],
      "interventions": [
        {
          "name": "Tegaserod",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2005-04",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2008-02-01",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 1,
      "location_summary": "East Hanover, New Jersey",
      "locations": [
        {
          "city": "East Hanover",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00171470"
    },
    {
      "nct_id": "NCT02505945",
      "title": "The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "GERD Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "Omeprazole",
          "type": "DRUG"
        },
        {
          "name": "LINX Reflux Management System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Torax Medical Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 152,
      "start_date": "2015-06",
      "completion_date": "2018-08",
      "has_results": true,
      "last_update_posted_date": "2019-01-07",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 21,
      "location_summary": "Mobile, Alabama • Heber Springs, Arkansas • Los Angeles, California + 18 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Heber Springs",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02505945"
    },
    {
      "nct_id": "NCT00492622",
      "title": "Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gastroparesis",
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "Immediate-release omeprazole",
          "type": "DRUG"
        },
        {
          "name": "Delayed-release omeprazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 12,
      "start_date": "2007-06",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2017-07-28",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00492622"
    },
    {
      "nct_id": "NCT04846010",
      "title": "Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Sequelae of; Infection",
        "Post Infection Glomerulonephritis",
        "Post-Infectious Peripheral Neuralgia",
        "Post-Infectious Disorder (Disorder)",
        "Post-Infectious Arthritis",
        "Post-Infectious Polyneuritis",
        "Post-Infectious Parkinsonism",
        "Post-Infectious Hypothyroidism",
        "Post Infectious Osteoarthritis",
        "Anxiety Disorders",
        "Depression",
        "Depression, Anxiety",
        "Depression, Bipolar",
        "Insomnia",
        "GERD",
        "Gastro Esophageal Reflux",
        "Hepatitis",
        "Glomerulonephritis"
      ],
      "interventions": [
        {
          "name": "PurWet",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "FurFat",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurApo",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurPhl",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurClo",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurInf",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Smoliv",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "All Natural Medicine Clinic, LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2000,
      "start_date": "2021-03-01",
      "completion_date": "2022-10-01",
      "has_results": false,
      "last_update_posted_date": "2021-05-26",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 1,
      "location_summary": "Rockville, Maryland",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04846010"
    },
    {
      "nct_id": "NCT00171457",
      "title": "The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Heartburn",
        "Dyspepsia"
      ],
      "interventions": [
        {
          "name": "Tegaserod",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2005-04",
      "completion_date": "2006-09",
      "has_results": false,
      "last_update_posted_date": "2007-10-10",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00171457"
    },
    {
      "nct_id": "NCT01129713",
      "title": "Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Gastroesophageal Reflux Disease (GERD)",
        "Heartburn",
        "Indigestion"
      ],
      "interventions": [
        {
          "name": "Secretol",
          "type": "DRUG"
        },
        {
          "name": "Nexium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Effexus Pharmaceutical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2010-05",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2014-08-05",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01129713"
    },
    {
      "nct_id": "NCT00236197",
      "title": "E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Heartburn"
      ],
      "interventions": [
        {
          "name": "rabeprazole sodium",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eisai Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 619,
      "start_date": "2005-10",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2009-11-11",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 1,
      "location_summary": "Lake Success, New York",
      "locations": [
        {
          "city": "Lake Success",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00236197"
    },
    {
      "nct_id": "NCT00373334",
      "title": "Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gastroesophageal Reflux Disease",
        "GERD",
        "Heartburn"
      ],
      "interventions": [
        {
          "name": "nizatidine (axid)",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Braintree Laboratories",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "30 Days to 1 Year"
      },
      "enrollment_count": 138,
      "start_date": "2006-08",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2009-11-18",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 26,
      "location_summary": "Hot Springs, Arkansas • Jonesboro, Arkansas • Little Rock, Arkansas + 22 more",
      "locations": [
        {
          "city": "Hot Springs",
          "state": "Arkansas"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Searcy",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00373334"
    },
    {
      "nct_id": "NCT05418439",
      "title": "Study to Evaluate the Efficacy of Poppi Apple Cider Vinegar Prebiotic Soda to Improve Gut Health In Participants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "IBS - Irritable Bowel Syndrome"
      ],
      "interventions": [
        {
          "name": "Drink Poppi Soda",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Drink Poppi",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 38,
      "start_date": "2022-04-01",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2022-06-15",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05418439"
    },
    {
      "nct_id": "NCT00627016",
      "title": "A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Dexlansoprazole",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 305,
      "start_date": "2008-03",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2011-04-28",
      "last_synced_at": "2026-06-11T04:10:35.843Z",
      "location_count": 43,
      "location_summary": "Tucson, Arizona • Anaheim, California • Garden Grove, California + 40 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Lancaster",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00627016"
    }
  ]
}