{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hereditary+Coproporphyria",
    "query": {
      "condition": "Hereditary Coproporphyria"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hereditary+Coproporphyria&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T09:03:51.919Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04883905",
      "title": "ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Hepatic Porphyria"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2021-04-26",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-27",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 13,
      "location_summary": "Birmingham, Alabama • Gilbert, Arizona • San Francisco, California + 10 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04883905"
    },
    {
      "nct_id": "NCT03906214",
      "title": "Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Porphyrias"
      ],
      "interventions": [
        {
          "name": "Web-based Survey",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "2019-04-03",
      "completion_date": "2019-09-13",
      "has_results": false,
      "last_update_posted_date": "2019-10-16",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03906214"
    },
    {
      "nct_id": "NCT00299195",
      "title": "A Randomized Study of Sulindac in Oral Premalignant Lesions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Leukoplakia, Oral",
        "Benign Neoplasms"
      ],
      "interventions": [
        {
          "name": "sulindac",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2006-02-23",
      "completion_date": "2020-01-06",
      "has_results": true,
      "last_update_posted_date": "2020-11-19",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00299195"
    },
    {
      "nct_id": "NCT05344599",
      "title": "Evaluating the Prevalence of Acute Hepatic Porphyria in Postural Tachycardia Syndrome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Postural Orthostatic Tachycardia Syndrome",
        "Acute Hepatic Porphyria"
      ],
      "interventions": [
        {
          "name": "Autonomic Function Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Genetic Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Urine Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood laboratory Testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 70,
      "start_date": "2022-01-19",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05344599"
    },
    {
      "nct_id": "NCT01561157",
      "title": "Longitudinal Study of the Porphyrias",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Porphyrias",
        "Cutaneous Porphyrias"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The American Porphyrias Expert Collaborative",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Minute and older"
      },
      "enrollment_count": 1500,
      "start_date": "2010-11-01",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 16,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • San Francisco, California + 13 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01561157"
    },
    {
      "nct_id": "NCT02240784",
      "title": "EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Hepatic Porphyria"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2014-08",
      "completion_date": "2021-04-26",
      "has_results": false,
      "last_update_posted_date": "2021-05-17",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 8,
      "location_summary": "San Francisco, California • Miami, Florida • Ann Arbor, Michigan + 5 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02240784"
    },
    {
      "nct_id": "NCT00680290",
      "title": "The Effect of Low Intensity Exercise on Quality of Life and Hemodynamics in Patients With Permanent Atrial Fibrillation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2007-07",
      "completion_date": "2009-07",
      "has_results": false,
      "last_update_posted_date": "2019-01-16",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00680290"
    },
    {
      "nct_id": "NCT03338816",
      "title": "ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Hepatic Porphyria",
        "Acute Intermittent Porphyria",
        "Porphyria, Acute Intermittent",
        "Acute Porphyria",
        "Hereditary Coproporphyria (HCP)",
        "Variegate Porphyria (VP)",
        "ALA Dehydratase Deficient Porphyria (ADP)"
      ],
      "interventions": [
        {
          "name": "Givosiran",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2017-11-16",
      "completion_date": "2021-05-31",
      "has_results": true,
      "last_update_posted_date": "2024-04-22",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 10,
      "location_summary": "Little Rock, Arkansas • San Francisco, California • Boston, Massachusetts + 7 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03338816"
    },
    {
      "nct_id": "NCT03547297",
      "title": "INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Hepatic Porphyria",
        "Hepatic Porphyrias",
        "Acute Intermittent Porphyria (AIP)",
        "Hereditary Coproporphyria (HCP)",
        "Variegate Porphyria (VP)",
        "ALA Dehydratase Deficient Porphyria (ADP)",
        "Porphyria Acute"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 212,
      "start_date": "2018-05-29",
      "completion_date": "2019-01-15",
      "has_results": false,
      "last_update_posted_date": "2019-01-25",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 12,
      "location_summary": "Pasadena, California • Jacksonville, Florida • Margate, Florida + 9 more",
      "locations": [
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Margate",
          "state": "Florida"
        },
        {
          "city": "Ames",
          "state": "Iowa"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03547297"
    },
    {
      "nct_id": "NCT02922413",
      "title": "Panhematin for Prevention of Acute Attacks of Porphyria",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Intermittent Porphyria",
        "Hereditary Coproporphyria",
        "Variegate Porphyria"
      ],
      "interventions": [
        {
          "name": "Hemin for injection",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2015-10-30",
      "completion_date": "2023-12-27",
      "has_results": true,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-06-26T09:03:51.919Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02922413"
    }
  ]
}