{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hereditary+Nonpolyposis+Colorectal+Cancer&page=3", "query": { "condition": "Hereditary Nonpolyposis Colorectal Cancer", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 78, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hereditary+Nonpolyposis+Colorectal+Cancer&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hereditary+Nonpolyposis+Colorectal+Cancer&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T19:07:16.530Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04508764", "title": "Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hereditary Breast and Ovarian Cancer", "Lynch Syndrome" ], "interventions": [ { "name": "Families Accelerating Cascade Testing Toolkit", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 96, "start_date": "2021-04-09", "completion_date": "2024-03-20", "has_results": false, "last_update_posted_date": "2024-04-16", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT04508764" }, { "nct_id": "NCT03832985", "title": "Pediatric Reporting of Adult-Onset Genomic Results", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Hereditary Breast and Ovarian Cancer Syndrome", "Lynch Syndrome", "Familial Hypercholesterolemia" ], "interventions": [ { "name": "Child(ren) receive an adult-onset result", "type": "GENETIC" }, { "name": "Child(ren) received a pediatric-onset result", "type": "GENETIC" }, { "name": "Control - Negative Result", "type": "GENETIC" }, { "name": "Adolescents who received adult-onset result", "type": "GENETIC" }, { "name": "Adolescents who received a pediatric-onset result", "type": "GENETIC" }, { "name": "Adolescent controls - negative for familial variant", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Geisinger Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 162, "start_date": "2020-11-25", "completion_date": "2024-10-31", "has_results": true, "last_update_posted_date": "2026-04-09", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 1, "location_summary": "Danville, Pennsylvania", "locations": [ { "city": "Danville", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03832985" }, { "nct_id": "NCT00582296", "title": "Multi-Organ Screening Recommendations in Patients With Lynch Syndrome", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lynch Syndrome" ], "interventions": [ { "name": "questionnaires, telephone interview, optional blood drawn", "type": "BEHAVIORAL" }, { "name": "questionnaires, telephone interview and optional blood drawn", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1530, "start_date": "2004-12", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-01-07", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 8, "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more", "locations": [ { "city": "Basking Ridge", "state": "New Jersey" }, { "city": "Middletown", "state": "New Jersey" }, { "city": "Montvale", "state": "New Jersey" }, { "city": "Commack", "state": "New York" }, { "city": "Harrison", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00582296" }, { "nct_id": "NCT02012699", "title": "Integrated Cancer Repository for Cancer Research", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pancreatic Cancer", "Thyroid Cancer", "Lung Cancer", "Esophageal Cancer", "Thymus Cancer", "Colon Cancer", "Rectal Cancer", "Gastrointestinal Stromal Tumors", "Anal Cancer", "Bile Duct Cancer", "Duodenal Cancer", "Gallbladder Cancer", "Gastric Cancer", "Liver Cancer", "Small Intestine Cancer", "Peritoneal Surface Malignancies", "Familial Adenomatous Polyposis", "Lynch Syndrome", "Bladder Cancer", "Kidney Cancer", "Penile Cancer", "Prostate Cancer", "Testicular Cancer", "Ureter Cancer", "Urethral Cancer", "Hypopharyngeal Cancer", "Laryngeal Cancer", "Lip Cancer", "Oral Cavity Cancer", "Nasopharyngeal Cancer", "Oropharyngeal Cancer", "Paranasal Sinus Cancer", "Nasal Cavity Cancer", "Salivary Gland Cancer", "Skin Cancer", "Central Nervous System Tumor", "Central Nervous System Cancer", "Mesothelioma", "Breast Cancer", "Leukemia", "Melanoma", "Sarcoma", "Unknown Primary Tumor", "Multiple Myeloma", "Ovarian Cancer", "Endometrial Cancer", "Vaginal Cancer", "Neuroendocrine Tumors", "Plasma Cell Dyscrasia", "Healthy Control" ], "interventions": [], "intervention_types": [], "sponsor": "University of Nebraska", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "19 Years", "maximum_age": "110 Years", "sex": "ALL", "summary": "19 Years to 110 Years" }, "enrollment_count": 999999, "start_date": "2013-11-01", "completion_date": "2099-12", "has_results": false, "last_update_posted_date": "2026-06-29", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 42, "location_summary": "Greenwood Village, Colorado • Manchester, Connecticut • Daytona Beach, Florida + 34 more", "locations": [ { "city": "Greenwood Village", "state": "Colorado" }, { "city": "Manchester", "state": "Connecticut" }, { "city": "Daytona Beach", "state": "Florida" }, { "city": "DeLand", "state": "Florida" }, { "city": "Orange City", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02012699" }, { "nct_id": "NCT07411599", "title": "Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial (\"Chip-CRC Trial\")", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Colorectal Cancer", "Peritoneal Metastases", "Carcinomatosis" ], "interventions": [ { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Fludarabine", "type": "DRUG" }, { "name": "Cetuximab", "type": "DRUG" }, { "name": "NK Cells", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2026-04-20", "completion_date": "2030-11-15", "has_results": false, "last_update_posted_date": "2026-10-05", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07411599" }, { "nct_id": "NCT03426878", "title": "Cancer Health Assessments Reaching Many", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hereditary Cancer Syndrome" ], "interventions": [ { "name": "Modified genetic counseling", "type": "OTHER" }, { "name": "Traditional genetic counseling", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Kaiser Permanente", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "49 Years", "sex": "ALL", "summary": "18 Years to 49 Years" }, "enrollment_count": 967, "start_date": "2018-08-15", "completion_date": "2022-02-01", "has_results": true, "last_update_posted_date": "2025-09-11", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 2, "location_summary": "Denver, Colorado • Portland, Oregon", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT03426878" }, { "nct_id": "NCT04494945", "title": "Identifying and Caring for Individuals With Inherited Cancer Syndrome", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome", "Breast Ductal Carcinoma In Situ", "Hematopoietic and Lymphoid System Neoplasm", "Hereditary Neoplastic Syndrome", "Lynch Syndrome", "Malignant Solid Neoplasm" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Genetic Counseling", "type": "OTHER" }, { "name": "Genetic Testing", "type": "OTHER" }, { "name": "Survey Administration", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "OHSU Knight Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 27500, "start_date": "2020-03-09", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 2, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT04494945" }, { "nct_id": "NCT03495674", "title": "Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "High-Frequency Microsatellite Instability", "Mismatch Repair Gene Mutation", "Mutation-Negative Lynch Syndrome", "Mutation-Positive Lynch Syndrome" ], "interventions": [ { "name": "Exercise Intervention", "type": "BEHAVIORAL" }, { "name": "Informational Intervention", "type": "OTHER" }, { "name": "Monitoring Device", "type": "DEVICE" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER", "DEVICE" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 21, "start_date": "2018-04-04", "completion_date": "2024-01-02", "has_results": false, "last_update_posted_date": "2024-01-05", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03495674" }, { "nct_id": "NCT00508846", "title": "Screening for Gynecologic Cancers in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Colon Cancer" ], "interventions": [ { "name": "Questionnaire", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": null, "sex": "FEMALE", "summary": "25 Years and older · Female only" }, "enrollment_count": 93, "start_date": "2003-05", "completion_date": "2016-03", "has_results": false, "last_update_posted_date": "2016-03-11", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00508846" }, { "nct_id": "NCT05257057", "title": "Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lynch Syndrome", "Endometrial Cancer", "Endometrial Hyperplasia", "Mismatch Repair Deficiency", "Microsatellite Instability" ], "interventions": [ { "name": "Immunohistochemical staining", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "WellSpan Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "FEMALE", "summary": "18 Years to 99 Years · Female only" }, "enrollment_count": 91, "start_date": "2019-05-08", "completion_date": "2023-06-02", "has_results": false, "last_update_posted_date": "2025-03-28", "last_synced_at": "2026-10-22T19:07:16.530Z", "location_count": 1, "location_summary": "York, Pennsylvania", "locations": [ { "city": "York", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05257057" } ] }