{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Herpes+Simplex+Labialis",
    "query": {
      "condition": "Herpes Simplex Labialis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 34,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Herpes+Simplex+Labialis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T06:10:54.973Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03521479",
      "title": "A Phase 2, Muti-Center Study of Repeat Dosing of Squaric Acid Dibutyl Ester in Subjects With Herpes Labialis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Herpes Labialis",
        "HSV"
      ],
      "interventions": [
        {
          "name": "Squaric Acid Dibutyl Ester",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Squarex, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-03-12",
      "completion_date": "2019-10-05",
      "has_results": true,
      "last_update_posted_date": "2021-08-06",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 2,
      "location_summary": "Doral, Florida • Saint Paul, Minnesota",
      "locations": [
        {
          "city": "Doral",
          "state": "Florida"
        },
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03521479"
    },
    {
      "nct_id": "NCT01308424",
      "title": "Safety and Efficacy Study of a New Treatment for Recurrent Symptoms of Oral Herpes Virus Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Oral Herpes Simplex"
      ],
      "interventions": [
        {
          "name": "BTL TML HSV",
          "type": "DRUG"
        },
        {
          "name": "Matching placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beech Tree Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 171,
      "start_date": "2011-01",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2013-08-13",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 4,
      "location_summary": "Lexington, Kentucky • Buffalo, New York • Norwich, New York + 1 more",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Norwich",
          "state": "New York"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01308424"
    },
    {
      "nct_id": "NCT03192306",
      "title": "Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for Episodic Treatment of Cold Sores",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Recurrent Herpes Labialis"
      ],
      "interventions": [
        {
          "name": "Merlin",
          "type": "DRUG"
        },
        {
          "name": "Ethanol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Topical Remedy",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 451,
      "start_date": "2017-07-05",
      "completion_date": "2018-04-02",
      "has_results": true,
      "last_update_posted_date": "2018-09-12",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 6,
      "location_summary": "Huntsville, Alabama • San Diego, California • Melbourne, Florida + 3 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Melbourne",
          "state": "Florida"
        },
        {
          "city": "Peoria",
          "state": "Illinois"
        },
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03192306"
    },
    {
      "nct_id": "NCT04893577",
      "title": "EDTA Eye Drops Compared to Abreva for Herpes Simplex Virus Eruptions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Herpes Simplex Oral"
      ],
      "interventions": [
        {
          "name": "EDTA",
          "type": "DRUG"
        },
        {
          "name": "Abreva",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2022-01-20",
      "completion_date": "2025-08-01",
      "has_results": true,
      "last_update_posted_date": "2025-10-31",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 1,
      "location_summary": "Murray, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04893577"
    },
    {
      "nct_id": "NCT02871492",
      "title": "Trial on Efficacy and Safety of Pritelivir Ointment for Treatment of Labial Herpes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Herpes Labialis"
      ],
      "interventions": [
        {
          "name": "Pritelivir 5% w/w ointment",
          "type": "DRUG"
        },
        {
          "name": "Pritelivir ointment matching placebo",
          "type": "DRUG"
        },
        {
          "name": "Zovirax® cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AiCuris Anti-infective Cures AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 362,
      "start_date": "2016-11-29",
      "completion_date": "2017-10-16",
      "has_results": true,
      "last_update_posted_date": "2021-07-13",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 10,
      "location_summary": "Scottsdale, Arizona • Santa Rosa, California • Pinellas Park, Florida + 7 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Santa Rosa",
          "state": "California"
        },
        {
          "city": "Pinellas Park",
          "state": "Florida"
        },
        {
          "city": "Edina",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02871492"
    },
    {
      "nct_id": "NCT01574612",
      "title": "Open Label Safety Study of Xerese Cream in the Treatment of Recurrent Herpes Labialis in Children 6-11 Years Old",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Herpes Labialis"
      ],
      "interventions": [
        {
          "name": "acyclovir/hydrocortisone cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Meda Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "6 Years to 11 Years"
      },
      "enrollment_count": 54,
      "start_date": "2012-03",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2014-05-22",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 10,
      "location_summary": "Los Angeles, California • Opa-locka, Florida • West Palm Beach, Florida + 7 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Opa-locka",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Addison",
          "state": "Illinois"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01574612"
    },
    {
      "nct_id": "NCT00297206",
      "title": "A Safety And Tolerability Study Of Valaciclovir Oral Suspension In Infants And Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Herpes Simplex"
      ],
      "interventions": [
        {
          "name": "Valaciclovir",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "1 Month to 6 Years"
      },
      "enrollment_count": 36,
      "start_date": "2003-01-25",
      "completion_date": "2007-02-28",
      "has_results": false,
      "last_update_posted_date": "2017-09-11",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • San Diego, California + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00297206"
    },
    {
      "nct_id": "NCT01324466",
      "title": "A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis (SHaRCS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Recurrent Herpes Labialis"
      ],
      "interventions": [
        {
          "name": "NB-001",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NanoBio Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 847,
      "start_date": "2011-04",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2013-05-23",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 35,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 31 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Burbank",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01324466"
    },
    {
      "nct_id": "NCT01971385",
      "title": "Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Herpes Labialis"
      ],
      "interventions": [
        {
          "name": "Squaric Acid solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 54,
      "start_date": "2013-10",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2017-10-02",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01971385"
    },
    {
      "nct_id": "NCT01306084",
      "title": "Viral Infections in Healthy and Immunocompromised Hosts",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anogenital Herpes",
        "COVID-19",
        "Herpes Labialis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "6 Months to 120 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2011-03-15",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-07-23T06:10:54.973Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01306084"
    }
  ]
}