{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Flow+Nasal+Cannula&page=2",
    "query": {
      "condition": "High Flow Nasal Cannula",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Flow+Nasal+Cannula&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:14:01.235Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00609882",
      "title": "Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Nasal CPAP",
          "type": "OTHER"
        },
        {
          "name": "Humidified High Flow Nasal Cannula (HHFNC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Weeks",
        "sex": "ALL",
        "summary": "Up to 8 Weeks"
      },
      "enrollment_count": 420,
      "start_date": "2007-12",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2013-02-06",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 8,
      "location_summary": "Philadelphia, Pennsylvania • Lackland Air Force Base, Texas • Ogden, Utah + 3 more",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        },
        {
          "city": "Ogden",
          "state": "Utah"
        },
        {
          "city": "Provo",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00609882"
    },
    {
      "nct_id": "NCT03738345",
      "title": "The Effects of Flow Settings During High Flow Nasal Cannula for Adult Hypoxemia Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxemia"
      ],
      "interventions": [
        {
          "name": "HFNC flow",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 49,
      "start_date": "2018-12-26",
      "completion_date": "2021-03-30",
      "has_results": false,
      "last_update_posted_date": "2021-04-23",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03738345"
    },
    {
      "nct_id": "NCT00990119",
      "title": "High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive",
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Vapotherm High Flow Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Non-invasive positive pressure ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2009-09",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2020-09-16",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00990119"
    },
    {
      "nct_id": "NCT02793674",
      "title": "HFNC Flow Titration and Effort of Breathing in the PICU",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "High Flow Nasal Cannula"
      ],
      "interventions": [
        {
          "name": "Fisher & Paykel high flow nasal cannula",
          "type": "DEVICE"
        },
        {
          "name": "Vapotherm high flow nasal cannula",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Years",
        "sex": "ALL",
        "summary": "Up to 3 Years"
      },
      "enrollment_count": 21,
      "start_date": "2014-09",
      "completion_date": "2016-07",
      "has_results": true,
      "last_update_posted_date": "2024-10-30",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02793674"
    },
    {
      "nct_id": "NCT03148262",
      "title": "High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Desaturation of Blood",
        "Obesity",
        "Colonoscopy",
        "Sleep Apnea",
        "High Flow Nasal Cannula"
      ],
      "interventions": [
        {
          "name": "The Comfort Flo system",
          "type": "DEVICE"
        },
        {
          "name": "The Salter nasal cannula",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 59,
      "start_date": "2017-05-10",
      "completion_date": "2018-01-22",
      "has_results": true,
      "last_update_posted_date": "2018-11-19",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03148262"
    },
    {
      "nct_id": "NCT05869825",
      "title": "HFNC vs NIPPV Following Extubation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "High Flow Nasal Canula following extubation",
          "type": "PROCEDURE"
        },
        {
          "name": "Non-Invasive Positive Pressure Ventilation following extubation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 200,
      "start_date": "2025-02-27",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05869825"
    },
    {
      "nct_id": "NCT02373683",
      "title": "Helium-oxygen Gas Mixtures Delivered by a High Flow Nasal Cannula in Bronchiolitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchiolitis",
        "Heliox",
        "Pediatrics"
      ],
      "interventions": [
        {
          "name": "Vapotherm-Heliox",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 10,
      "start_date": "2014-12",
      "completion_date": "2015-11",
      "has_results": true,
      "last_update_posted_date": "2022-03-02",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02373683"
    },
    {
      "nct_id": "NCT02236559",
      "title": "High Flow Therapy for the Treatment of Respiratory Failure in the ED",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Noninvasive positive pressure ventilation (NIPPV)",
          "type": "DEVICE"
        },
        {
          "name": "Vapotherm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 204,
      "start_date": "2014-09",
      "completion_date": "2017-02",
      "has_results": true,
      "last_update_posted_date": "2019-05-23",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 5,
      "location_summary": "Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more",
      "locations": [
        {
          "city": "Athens",
          "state": "Georgia"
        },
        {
          "city": "Florence",
          "state": "South Carolina"
        },
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02236559"
    },
    {
      "nct_id": "NCT04517344",
      "title": "High Flow Nasal Cannula (HFNC) Initiation Flow Rate Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchiolitis"
      ],
      "interventions": [
        {
          "name": "Initial Flow Rate",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "7 Days to 12 Months"
      },
      "enrollment_count": 21,
      "start_date": "2020-12-01",
      "completion_date": "2025-04-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04517344"
    },
    {
      "nct_id": "NCT04694638",
      "title": "Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prone Positioning",
        "Covid19",
        "Hypoxemic Respiratory Failure",
        "ARDS",
        "Non Invasive Ventilation",
        "High Flow Nasal Cannulla"
      ],
      "interventions": [
        {
          "name": "Body position change",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 6,
      "start_date": "2020-05-21",
      "completion_date": "2023-05-10",
      "has_results": false,
      "last_update_posted_date": "2023-10-05",
      "last_synced_at": "2026-05-22T05:14:01.235Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04694638"
    }
  ]
}