{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Grade&page=20", "query": { "condition": "High Grade", "page": 20 }, "page_size": 10 }, "pagination": { "page": 20, "page_size": 10, "total_count": 7763, "total_pages": 777, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Grade&page=21&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Grade&page=19&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T10:44:04.243Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01621178", "title": "A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes", "Chronic Kidney Disease" ], "interventions": [ { "name": "Dulaglutide", "type": "DRUG" }, { "name": "Insulin glargine", "type": "DRUG" }, { "name": "Insulin lispro", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 577, "start_date": "2012-07", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2019-09-19", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 47, "location_summary": "Montgomery, Alabama • Azusa, California • Granada Hills, California + 39 more", "locations": [ { "city": "Montgomery", "state": "Alabama" }, { "city": "Azusa", "state": "California" }, { "city": "Granada Hills", "state": "California" }, { "city": "Greenbrae", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01621178" }, { "nct_id": "NCT02348216", "title": "Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Refractory Diffuse Large B Cell Lymphoma (DLBCL)", "Relapsed Diffuse Large B-Cell Lymphoma", "Transformed Follicular Lymphoma (TFL)", "Primary Mediastinal B-cell Lymphoma (PMBCL)", "High Grade B-cell Lymphoma (HGBCL)" ], "interventions": [ { "name": "Axicabtagene Ciloleucel", "type": "BIOLOGICAL" }, { "name": "Fludarabine", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Levetiracetam", "type": "DRUG" }, { "name": "Tocilizumab", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "High-dose methylprednisolone", "type": "DRUG" }, { "name": "Bendamustine", "type": "DRUG" }, { "name": "Rituximab", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Vincristine", "type": "DRUG" }, { "name": "Ifosfamide", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Etoposide", "type": "DRUG" }, { "name": "Gemcitabine", "type": "DRUG" }, { "name": "Oxaliplatin", "type": "DRUG" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Methylprednisolone", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Kite, A Gilead Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 307, "start_date": "2015-04-21", "completion_date": "2023-07-27", "has_results": true, "last_update_posted_date": "2024-06-04", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 23, "location_summary": "Gilbert, Arizona • Duarte, California • La Jolla, California + 19 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Duarte", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02348216" }, { "nct_id": "NCT06013384", "title": "Low-Intensity Focused Ultrasound for Treatment-Resistant Depression", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder", "Treatment Resistant Depression" ], "interventions": [ { "name": "Low-Intensity Focused Ultrasound Pulsation", "type": "DEVICE" }, { "name": "Sham Low-Intensity Focused Ultrasound Pulsation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 1, "start_date": "2024-02-16", "completion_date": "2028-06", "has_results": false, "last_update_posted_date": "2026-01-12", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06013384" }, { "nct_id": "NCT00098358", "title": "Study of Oral Zileuton in the Treatment of Moderate to Severe Facial Acne Vulgaris", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acne Vulgaris" ], "interventions": [ { "name": "Zileuton", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Critical Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 90, "start_date": "2004-11", "completion_date": "2005-05", "has_results": false, "last_update_posted_date": "2007-02-07", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 12, "location_summary": "San Diego, California • Newnan, Georgia • Louisville, Kentucky + 9 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Newnan", "state": "Georgia" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Fridley", "state": "Minnesota" }, { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT00098358" }, { "nct_id": "NCT06049017", "title": "A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colitis, Ulcerative" ], "interventions": [ { "name": "JNJ-77242113", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 252, "start_date": "2023-10-09", "completion_date": "2026-01-05", "has_results": false, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 32, "location_summary": "Anaheim, California • Newport Beach, California • San Diego, California + 28 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Kissimmee", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06049017" }, { "nct_id": "NCT02059499", "title": "Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Anal Intraepithelial Neoplasia", "High-grade Squamous Intraepithelial Lesion", "HIV Infection" ], "interventions": [ { "name": "imiquimod", "type": "DRUG" }, { "name": "fluorouracil", "type": "DRUG" }, { "name": "questionnaire administration", "type": "OTHER" }, { "name": "laboratory biomarker analysis", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "AIDS Malignancy Consortium", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 91, "start_date": "2015-12-28", "completion_date": "2024-05-02", "has_results": true, "last_update_posted_date": "2025-07-23", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 12, "location_summary": "Los Angeles, California • San Francisco, California • Atlanta, Georgia + 6 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "New Orleans", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02059499" }, { "nct_id": "NCT05570006", "title": "Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ulcerative Colitis" ], "interventions": [ { "name": "ABBV-668", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2023-03-16", "completion_date": "2024-12-23", "has_results": true, "last_update_posted_date": "2025-12-23", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 18, "location_summary": "Chula Vista, California • Maitland, Florida • Margate, Florida + 13 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Maitland", "state": "Florida" }, { "city": "Margate", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Macon", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05570006" }, { "nct_id": "NCT02502149", "title": "Pharmacokinetics and Safety of rFVIIIFc Manufactured at 15,000 L (15K) Scale", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Severe Hemophilia A" ], "interventions": [ { "name": "rFVIIIFc", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Bioverativ Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "MALE", "summary": "12 Years and older · Male only" }, "enrollment_count": 24, "start_date": "2015-08", "completion_date": "2017-06", "has_results": true, "last_update_posted_date": "2020-12-19", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 8, "location_summary": "Los Angeles, California • Chicago, Illinois • Indianapolis, Indiana + 5 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "East Lansing", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02502149" }, { "nct_id": "NCT05848115", "title": "BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Asthma in Children" ], "interventions": [ { "name": "Bi-level Positive Airway Pressure", "type": "DEVICE" }, { "name": "Sham Bi-level Positive Airway Pressure", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "5 Years to 17 Years" }, "enrollment_count": 67, "start_date": "2023-06-23", "completion_date": "2025-07-07", "has_results": false, "last_update_posted_date": "2025-08-21", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05848115" }, { "nct_id": "NCT06359015", "title": "Metformin and Esomeprazole in Preterm Pre-eclampsia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Preeclampsia Severe", "Pre-Eclampsia", "Preeclampsia", "Preeclampsia Second Trimester", "Preeclampsia Complicating Childbirth", "Preeclampsia Puerperium", "Preterm" ], "interventions": [ { "name": "Metformin", "type": "DRUG" }, { "name": "Esomeprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Christiana Care Health Services", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "18 Years to 60 Years · Female only" }, "enrollment_count": 4, "start_date": "2021-02-11", "completion_date": "2025-05-08", "has_results": false, "last_update_posted_date": "2025-05-31", "last_synced_at": "2026-10-22T10:44:04.243Z", "location_count": 1, "location_summary": "Newark, Delaware", "locations": [ { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT06359015" } ] }