{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Grade&page=4", "query": { "condition": "High Grade", "page": 4 }, "page_size": 10 }, "pagination": { "page": 4, "page_size": 10, "total_count": 7762, "total_pages": 777, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Grade&page=5&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=High+Grade&page=3&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-20T13:05:58.813Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00036894", "title": "CC-5013 in Treating Patients With Recurrent Glioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Brain and Central Nervous System Tumors" ], "interventions": [ { "name": "lenalidomide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": null, "start_date": "2002-03", "completion_date": null, "has_results": false, "last_update_posted_date": "2015-04-30", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00036894" }, { "nct_id": "NCT00859222", "title": "LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Malignant Glioma" ], "interventions": [ { "name": "LBH589", "type": "DRUG" }, { "name": "bevacizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Patrick Y. Wen, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 51, "start_date": "2009-03", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2017-03-14", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 5, "location_summary": "Chicago, Illinois • Boston, Massachusetts • Charlottesville, Virginia", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Charlottesville", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00859222" }, { "nct_id": "NCT00547729", "title": "Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "HeartPOD™ System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 71, "start_date": "2005-03", "completion_date": "2008-06", "has_results": true, "last_update_posted_date": "2021-09-02", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 4, "location_summary": "La Jolla, California • Los Angeles, California • Columbus, Ohio + 1 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT00547729" }, { "nct_id": "NCT06444451", "title": "A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alopecia Areata" ], "interventions": [ { "name": "Amlitelimab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 166, "start_date": "2024-06-06", "completion_date": "2026-05-21", "has_results": false, "last_update_posted_date": "2026-08-10", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 17, "location_summary": "Birmingham, Alabama • Fountain Valley, California • Fremont, California + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Fremont", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06444451" }, { "nct_id": "NCT01198002", "title": "A Rheumatoid Arthritis Study in Participants on a Background Treatment of Methotrexate", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "LY2127399", "type": "DRUG" }, { "name": "Placebo Q2W", "type": "DRUG" }, { "name": "Placebo Q4W", "type": "DRUG" }, { "name": "Methotrexate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1041, "start_date": "2010-12", "completion_date": "2014-01", "has_results": true, "last_update_posted_date": "2018-05-08", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 75, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Paradise Valley, Arizona + 72 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Paradise Valley", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01198002" }, { "nct_id": "NCT00004031", "title": "SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Lymphoma" ], "interventions": [ { "name": "rituximab", "type": "BIOLOGICAL" }, { "name": "CHOP regimen", "type": "DRUG" }, { "name": "carmustine", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "doxorubicin hydrochloride", "type": "DRUG" }, { "name": "etoposide", "type": "DRUG" }, { "name": "prednisone", "type": "DRUG" }, { "name": "vincristine sulfate", "type": "DRUG" }, { "name": "bone marrow ablation with stem cell support", "type": "PROCEDURE" }, { "name": "peripheral blood stem cell transplantation", "type": "PROCEDURE" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "PROCEDURE", "RADIATION" ], "sponsor": "SWOG Cancer Research Network", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "15 Years to 65 Years" }, "enrollment_count": 397, "start_date": "1997-07", "completion_date": "2013-10-31", "has_results": true, "last_update_posted_date": "2021-02-02", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT00004031" }, { "nct_id": "NCT01312922", "title": "Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "PNB01 fixed dose combination of pipamperone and citalopram", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Pipamperone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "PharmaNeuroBoost N.V.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 555, "start_date": "2011-09", "completion_date": "2012-12", "has_results": true, "last_update_posted_date": "2022-04-07", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 26, "location_summary": "Glendale, California • National City, California • Riverside, California + 22 more", "locations": [ { "city": "Glendale", "state": "California" }, { "city": "National City", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01312922" }, { "nct_id": "NCT00437151", "title": "Analysis of Adherence & Associated Factors in Teenagers Undergoing Treatment of Acne Vulgaris With Differin® Gel 0.1%", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Acne" ], "interventions": [ { "name": "More frequent than normal office visits", "type": "OTHER" }, { "name": "Electronic reminders (voice, e-mail, text messages)", "type": "OTHER" }, { "name": "Parenteral involvement / intervention reminders", "type": "OTHER" }, { "name": "No intervention or reminders", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Galderma R&D", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "13 Years to 18 Years" }, "enrollment_count": 61, "start_date": "2006-06", "completion_date": "2007-06", "has_results": false, "last_update_posted_date": "2022-07-29", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00437151" }, { "nct_id": "NCT04154631", "title": "Implementing and Sustaining a Sleep Treatment to Improve Community Mental Part 1: Implementation Health Outcomes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sleep Disorder", "Circadian Dysregulation" ], "interventions": [ { "name": "Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)", "type": "BEHAVIORAL" }, { "name": "Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)", "type": "BEHAVIORAL" }, { "name": "Usual Care Delayed Treatment", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "University of California, Berkeley", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 489, "start_date": "2020-01-08", "completion_date": "2023-12-19", "has_results": true, "last_update_posted_date": "2025-10-27", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 10, "location_summary": "Concord, California • Fairfield, California • Goleta, California + 7 more", "locations": [ { "city": "Concord", "state": "California" }, { "city": "Fairfield", "state": "California" }, { "city": "Goleta", "state": "California" }, { "city": "Hanford", "state": "California" }, { "city": "Lucerne", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04154631" }, { "nct_id": "NCT01074502", "title": "Apremilast in the Treatment of Moderate to Severe Acne", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acne" ], "interventions": [ { "name": "apremilast", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 3, "start_date": "2010-02", "completion_date": "2010-10", "has_results": true, "last_update_posted_date": "2017-03-13", "last_synced_at": "2026-10-20T13:05:58.813Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01074502" } ] }