{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hirschsprung%27s+Disease",
    "query": {
      "condition": "Hirschsprung's Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hirschsprung%27s+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T10:18:00.047Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00671684",
      "title": "Endoscopic Mucosal Resection (EMR) for Diagnosis of Hirschsprung's Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Constipation",
        "Hirschsprung's Disease"
      ],
      "interventions": [
        {
          "name": "Endoscopic Mucosal Resection (EMR)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2007-10",
      "completion_date": "2009-04",
      "has_results": false,
      "last_update_posted_date": "2008-05-05",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00671684"
    },
    {
      "nct_id": "NCT04476225",
      "title": "Induced Pluripotent Stem Cells for Disease Research",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hirschsprung Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "13 Years to 100 Years"
      },
      "enrollment_count": 1,
      "start_date": "2022-04-15",
      "completion_date": "2022-10-03",
      "has_results": false,
      "last_update_posted_date": "2022-10-06",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04476225"
    },
    {
      "nct_id": "NCT00478712",
      "title": "Hirschsprung Disease Genetic Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hirschsprung Disease"
      ],
      "interventions": [
        {
          "name": "Identification of genetic causes of Hirschsprung Disease",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Week",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "1 Week to 100 Years"
      },
      "enrollment_count": 3000,
      "start_date": "2001-01",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00478712"
    },
    {
      "nct_id": "NCT06072976",
      "title": "The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastrointestinal Complication",
        "Intestinal Obstruction",
        "Gastroschisis",
        "Hirschsprung Disease",
        "Omphalocele",
        "Midgut Volvulus"
      ],
      "interventions": [
        {
          "name": "Standard of Care",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Exclusive Human Milk",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "0 Days to 55 Years"
      },
      "enrollment_count": 116,
      "start_date": "2023-06-09",
      "completion_date": "2027-06-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06072976"
    },
    {
      "nct_id": "NCT01515501",
      "title": "Endoscopic Mucosal Resection for the Diagnosis of a-Ganglionosis, a Controlled Prospective Trial (EDGE Trial)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Constipation",
        "Hirschsprung Disease"
      ],
      "interventions": [
        {
          "name": "Endoscopic mucosal resection (EMR)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2007-10",
      "completion_date": "2018-08",
      "has_results": false,
      "last_update_posted_date": "2018-08-16",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01515501"
    },
    {
      "nct_id": "NCT05038345",
      "title": "Hirschsprung Disease Trends in the United States: Analysis of the National Inpatient Sample",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hirschsprung Disease"
      ],
      "interventions": [
        {
          "name": "Pull through surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Day to 18 Years"
      },
      "enrollment_count": 2787,
      "start_date": "2019-03-13",
      "completion_date": "2021-08-15",
      "has_results": false,
      "last_update_posted_date": "2025-02-24",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05038345"
    },
    {
      "nct_id": "NCT00630838",
      "title": "Probiotic Prophylaxis of Hirschprung's Disease Associated Enterocolitis (HAEC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hirschsprung Disease"
      ],
      "interventions": [
        {
          "name": "VSL#3",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "1 Month to 12 Months"
      },
      "enrollment_count": 62,
      "start_date": "2006-09",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2016-07-19",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan • Buffalo, New York",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00630838"
    },
    {
      "nct_id": "NCT02193685",
      "title": "Identification Genetic, Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung Disease",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hirschsprung Disease",
        "Enterocolitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "1 Day to 17 Years"
      },
      "enrollment_count": 400,
      "start_date": "2010-02",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2016-08-12",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02193685"
    },
    {
      "nct_id": "NCT03626350",
      "title": "Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gastrointestinal Neoplasia",
        "Hirschsprung's Disease",
        "Esophageal Obstruction",
        "Gastroparesis",
        "Spastic Esophageal Disorders",
        "Zenker's Diverticulum"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 250,
      "start_date": "2018-06-12",
      "completion_date": "2025-06-12",
      "has_results": false,
      "last_update_posted_date": "2024-05-21",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03626350"
    },
    {
      "nct_id": "NCT03088020",
      "title": "International Congenital Central Hypoventilation Syndrome (CCHS) Registry and CCHS SHARE",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Central Hypoventilation Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Debra Weese-Mayer",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2013-06-24",
      "completion_date": "2032-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-06-10T10:18:00.047Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03088020"
    }
  ]
}