{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hookah+Smoking",
    "query": {
      "condition": "Hookah Smoking"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hookah+Smoking&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:50:07.616Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03166787",
      "title": "Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smoking",
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Charcoal hookah",
          "type": "OTHER"
        },
        {
          "name": "E-coal hookah",
          "type": "OTHER"
        },
        {
          "name": "Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Carbon Monoxide inhalation",
          "type": "DRUG"
        },
        {
          "name": "Room Air inhalation",
          "type": "OTHER"
        },
        {
          "name": "vitamin C",
          "type": "DRUG"
        },
        {
          "name": "tadalafil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "21 Years to 49 Years"
      },
      "enrollment_count": 60,
      "start_date": "2017-08-15",
      "completion_date": "2020-10-15",
      "has_results": false,
      "last_update_posted_date": "2021-04-09",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03166787"
    },
    {
      "nct_id": "NCT03616002",
      "title": "Effects of Hookah (Waterpipe) Smoking on Blood Vessel Function",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hookah Smoking"
      ],
      "interventions": [
        {
          "name": "Hookah smoking",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "18 Years to 29 Years"
      },
      "enrollment_count": 58,
      "start_date": "2015-01-01",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2021-02-04",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03616002"
    },
    {
      "nct_id": "NCT01974063",
      "title": "Alternate Nicotine Delivery Systems and Airway Epithelial Biology",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Smoking",
        "Smoking Cessation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2013-03",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2018-05-03",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01974063"
    },
    {
      "nct_id": "NCT06316947",
      "title": "Developing and Pilot Testing an Intervention to Reduce Household Shisha Smoke Exposure Within Somali Homes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shisha"
      ],
      "interventions": [
        {
          "name": "CHW-delivered intervention",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Months and older"
      },
      "enrollment_count": 15,
      "start_date": "2025-09-03",
      "completion_date": "2026-03-15",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06316947"
    },
    {
      "nct_id": "NCT03690427",
      "title": "The Cardiovascular Effects of Electronic Hookah Vaping",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endothelial Dysfunction",
        "Inflammation",
        "Oxidative Stress"
      ],
      "interventions": [
        {
          "name": "Traditional hookah smoking",
          "type": "OTHER"
        },
        {
          "name": "Electronic hookah vaping",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "21 Years to 39 Years"
      },
      "enrollment_count": 19,
      "start_date": "2018-12-11",
      "completion_date": "2021-09-27",
      "has_results": true,
      "last_update_posted_date": "2023-08-16",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03690427"
    },
    {
      "nct_id": "NCT02310373",
      "title": "Effects of Nicotine-Free Hookah Smoking on Blood Flow to the Heart, Muscle and Skin",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Nicotine-free Hookah Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine free hookah smoking",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 9,
      "start_date": "2014-11",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2020-01-13",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02310373"
    },
    {
      "nct_id": "NCT00992550",
      "title": "Comparison of Hookah and Cigarette Smoking",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Cigarette",
          "type": "DRUG"
        },
        {
          "name": "Hookah",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 13,
      "start_date": "2009-10",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2013-05-24",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00992550"
    },
    {
      "nct_id": "NCT03096860",
      "title": "Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use, Unspecified",
        "Hookah Smoking"
      ],
      "interventions": [
        {
          "name": "Active alcohol consumption",
          "type": "OTHER"
        },
        {
          "name": "Placebo consumption",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oklahoma State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2017-02-22",
      "completion_date": "2017-10-10",
      "has_results": false,
      "last_update_posted_date": "2017-10-13",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03096860"
    },
    {
      "nct_id": "NCT04661683",
      "title": "Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hookah Smoking",
        "Secondhand Aerosol",
        "Vascular Stiffness",
        "Vaping"
      ],
      "interventions": [
        {
          "name": "Combustible Hookah Smoke",
          "type": "OTHER"
        },
        {
          "name": "Electronic Hookah Aerosol",
          "type": "OTHER"
        },
        {
          "name": "Clean Room Air",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "21 Years to 49 Years"
      },
      "enrollment_count": 12,
      "start_date": "2021-06-25",
      "completion_date": "2027-04-15",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04661683"
    },
    {
      "nct_id": "NCT05705375",
      "title": "Effect of Waterpipe Size on Smoking Behavior and Exposures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Waterpipe Size"
      ],
      "interventions": [
        {
          "name": "Waterpipe size",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Texas at Arlington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "21 Years to 39 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-04-22",
      "completion_date": "2024-03-30",
      "has_results": true,
      "last_update_posted_date": "2025-11-05",
      "last_synced_at": "2026-05-22T04:50:07.616Z",
      "location_count": 1,
      "location_summary": "Arlington, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05705375"
    }
  ]
}