{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Host+Disease+Manifestation&page=2",
    "query": {
      "condition": "Host Disease Manifestation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Host+Disease+Manifestation&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Host+Disease+Manifestation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-05T04:00:25.224Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00521196",
      "title": "Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "DC Stimulator (Transcranial Direct Current Stimulator)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 13,
      "start_date": "2007-07",
      "completion_date": "2012-01-13",
      "has_results": false,
      "last_update_posted_date": "2017-03-21",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00521196"
    },
    {
      "nct_id": "NCT06288217",
      "title": "Non-invasive Trigeminal and Vagus Nerve Stimulation for Stroke Subjects With Chronic Upper Extremity Deficits",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Upper Extremity Paresis",
        "Stroke, Chronic"
      ],
      "interventions": [
        {
          "name": "NeuraStasis Stimulator System (Non-Invasive Trigeminal and Vagus Nerve Stimulation)",
          "type": "DEVICE"
        },
        {
          "name": "Upper Limb Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Sham Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "NeuraStasis, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "30 Years to 85 Years"
      },
      "enrollment_count": 16,
      "start_date": "2024-03-05",
      "completion_date": "2025-11-13",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06288217"
    },
    {
      "nct_id": "NCT05206630",
      "title": "ED Physical Therapy for Chronic Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "ED Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 128,
      "start_date": "2022-01-11",
      "completion_date": "2025-07-25",
      "has_results": false,
      "last_update_posted_date": "2025-10-14",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05206630"
    },
    {
      "nct_id": "NCT06841770",
      "title": "A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Spinal Cord Injury Cervical",
        "Spinal Cord Injury Thoracic",
        "Spinal Cord Injury, Acute",
        "Spinal Cord Injury",
        "Spinal Cord Injury, Chronic"
      ],
      "interventions": [
        {
          "name": "OPC1",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Lineage Cell Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2025-06-30",
      "completion_date": "2037-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 2,
      "location_summary": "Downey, California • La Jolla, California",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06841770"
    },
    {
      "nct_id": "NCT02605135",
      "title": "Host Response to Pessaries in Microbial Communities of the Postmenopausal Vagina",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stress Urinary Incontinence",
        "Prolapse"
      ],
      "interventions": [
        {
          "name": "Continued Pessary Use",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Loyola University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "51 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "51 Years and older · Female only"
      },
      "enrollment_count": 84,
      "start_date": "2016-04",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2019-01-22",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "Maywood, Illinois",
      "locations": [
        {
          "city": "Maywood",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02605135"
    },
    {
      "nct_id": "NCT01421160",
      "title": "Regulating Urine pH Levels to Alleviate Chronic Joint Pain",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "sodium citrate and citric acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Texas Tech University Health Sciences Center, El Paso",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2011-07",
      "completion_date": "2012-03",
      "has_results": false,
      "last_update_posted_date": "2017-05-16",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "El Paso, Texas",
      "locations": [
        {
          "city": "El Paso",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01421160"
    },
    {
      "nct_id": "NCT00360685",
      "title": "Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mucositis",
        "Graft-versus-host Disease"
      ],
      "interventions": [
        {
          "name": "Tac+MTX",
          "type": "DRUG"
        },
        {
          "name": "TAC + MMF",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 89,
      "start_date": "2005-09",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2013-05-03",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00360685"
    },
    {
      "nct_id": "NCT01976598",
      "title": "Sub-Sensory Intraspinal Neurostimulation Therapy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Back Pain",
        "Back Pain With Radiation",
        "Pain in Leg, Unspecified"
      ],
      "interventions": [
        {
          "name": "Sub-Sensory Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Algos Clinical Development Thomas L. Yearwood, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 1,
      "start_date": "2013-10",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-01-19",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "Pascagoula, Mississippi",
      "locations": [
        {
          "city": "Pascagoula",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01976598"
    },
    {
      "nct_id": "NCT04087291",
      "title": "Veterans Response to Dosage in Chiropractic Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Patient Acceptance of Health Care",
        "Veterans Health"
      ],
      "interventions": [
        {
          "name": "Chiropractic Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 766,
      "start_date": "2021-02-22",
      "completion_date": "2025-05-20",
      "has_results": true,
      "last_update_posted_date": "2026-08-11",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • West Haven, Connecticut • Iowa City, Iowa + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "West Haven",
          "state": "Connecticut"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04087291"
    },
    {
      "nct_id": "NCT06419439",
      "title": "Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Low Back Pain",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Ketamine hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Minimally Enhanced Usual Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Brief narrative intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2025-12-03",
      "completion_date": "2029-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-10-05T04:00:25.224Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06419439"
    }
  ]
}