{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Human+Milk+Fortification",
    "query": {
      "condition": "Human Milk Fortification"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Human+Milk+Fortification&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T23:04:44.395Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00506584",
      "title": "Randomized Study of Human-Milk Based Nutrition Versus Formula in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Very Low Birth Weight"
      ],
      "interventions": [
        {
          "name": "Pasteurized human milk and pasteurized human milk fortifier",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Human milk fortifier (bovine-based), pre-term formula",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Pre-term/term formula",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Prolacta Bioscience",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "1 Day to 21 Days"
      },
      "enrollment_count": 260,
      "start_date": "2007-07",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2010-02-18",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 12,
      "location_summary": "Berkeley, California • San Diego, California • New Haven, Connecticut + 9 more",
      "locations": [
        {
          "city": "Berkeley",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00506584"
    },
    {
      "nct_id": "NCT04025021",
      "title": "Targeted Breast Milk Fortification for Very Low Birth Weight Infants in the NICU",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Milk",
        "Neonate",
        "Breast Milk"
      ],
      "interventions": [
        {
          "name": "Targeted Fortification",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "The Miris Human Milk Analyzer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DEVICE"
      ],
      "sponsor": "MetroHealth Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 3,
      "start_date": "2019-10-01",
      "completion_date": "2021-03-31",
      "has_results": true,
      "last_update_posted_date": "2023-02-23",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04025021"
    },
    {
      "nct_id": "NCT04284280",
      "title": "Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Poor Growth in Extremely Preterm Infants",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Routine vs Selective use of Human Milk Donor Fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Crouse Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "6 Days",
        "sex": "ALL",
        "summary": "0 Days to 6 Days"
      },
      "enrollment_count": 170,
      "start_date": "2020-02-15",
      "completion_date": "2025-11-11",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "Syracuse, New York",
      "locations": [
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04284280"
    },
    {
      "nct_id": "NCT04294368",
      "title": "Targeted Fortification of Donor Breast Milk in Preterm Infants",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity; Extreme",
        "Failure to Thrive in Newborn",
        "Growth Retardation",
        "Growth Failure",
        "Infant Nutrition Disorders"
      ],
      "interventions": [
        {
          "name": "Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac Liquid Protein Fortifier",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Nestle Microlipid",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Medica Nutrition SolCarb",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac Liquid Protein Fortifier (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Nestle Microlipid (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Medica Nutrition SolCarb (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Analysis with Miris (AB) Human Milk Analyzer",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "1 Day to 21 Days"
      },
      "enrollment_count": 50,
      "start_date": "2020-03-09",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04294368"
    },
    {
      "nct_id": "NCT02943746",
      "title": "Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Infants"
      ],
      "interventions": [
        {
          "name": "Standard Protein Diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High Protein Diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Days",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Days and older"
      },
      "enrollment_count": 118,
      "start_date": "2016-11",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02943746"
    },
    {
      "nct_id": "NCT05228535",
      "title": "Human Milk in Preterm Infants",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Human milk fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "4 Days",
        "sex": "ALL",
        "summary": "Up to 4 Days"
      },
      "enrollment_count": 50,
      "start_date": "2022-04-11",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2022-07-21",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05228535"
    },
    {
      "nct_id": "NCT01988792",
      "title": "Human Milk Fortification in Very Low Birth Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature; Infant",
        "Enteral Nutrition",
        "Human Milk",
        "Fortification"
      ],
      "interventions": [
        {
          "name": "Human milk fortifiers",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Days",
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "2 Days to 7 Days"
      },
      "enrollment_count": 100,
      "start_date": "2013-11",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-07-29",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01988792"
    },
    {
      "nct_id": "NCT00760942",
      "title": "Liquid Preterm Formula Versus Powdered Human Milk Fortifier in VLBW Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Very Low Birth Weight"
      ],
      "interventions": [
        {
          "name": "Similac special care 30",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac human milk fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "10 Weeks",
        "sex": "ALL",
        "summary": "1 Day to 10 Weeks"
      },
      "enrollment_count": 84,
      "start_date": "2008-10",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2013-12-10",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00760942"
    },
    {
      "nct_id": "NCT04190875",
      "title": "Post-Discharge Growth and Development of Infants Who Received Targeted Fortification in the NICU",
      "overall_status": "SUSPENDED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Premature Infants"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": "24 Months",
        "sex": "ALL",
        "summary": "18 Months to 24 Months"
      },
      "enrollment_count": 120,
      "start_date": "2019-02-20",
      "completion_date": "2027-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04190875"
    },
    {
      "nct_id": "NCT06870981",
      "title": "Optimizing Nutrition and Milk (Opti-NuM) Project",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Very Low Birth Weight Baby",
        "Early Nutrition and the Preterm Infant",
        "Nutritional Requirements",
        "Human Milk Fortification",
        "Human Milk Microbiome",
        "Human Milk Feeding",
        "Human Milk Nutrition",
        "Growth &Amp; Development"
      ],
      "interventions": [
        {
          "name": "Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Hospital for Sick Children",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "1 Hour to 21 Days"
      },
      "enrollment_count": 1100,
      "start_date": "2010-10-01",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-03-11",
      "last_synced_at": "2026-06-10T23:04:44.395Z",
      "location_count": 2,
      "location_summary": "Palo Alto, California • San Diego, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06870981"
    }
  ]
}