{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Humoral+Hypercalcemia+of+Malignancy",
    "query": {
      "condition": "Humoral Hypercalcemia of Malignancy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T13:04:38.069Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00060138",
      "title": "Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Hypercalcemia of Malignancy",
        "Metastatic Cancer",
        "Pain"
      ],
      "interventions": [
        {
          "name": "monoclonal antibody CAL",
          "type": "BIOLOGICAL"
        },
        {
          "name": "zoledronic acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Chugai Pharmaceutical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": null,
      "start_date": "2002-11",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2013-05-15",
      "last_synced_at": "2026-07-22T13:04:38.069Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060138"
    },
    {
      "nct_id": "NCT01333267",
      "title": "One Week Comparison Study of PTH and PTHrP Infusions",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteoporosis",
        "Hypercalcemia of Malignancy",
        "Hyperparathyroidism",
        "Bone Diseases, Endocrine"
      ],
      "interventions": [
        {
          "name": "Parathyroid Hormone-related Protein (1-36)",
          "type": "DRUG"
        },
        {
          "name": "parathyroid hormone (1-34)",
          "type": "DRUG"
        },
        {
          "name": "PTH (1-34) and PTHrP (1-36)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "24 Years to 35 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-01",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2014-12-05",
      "last_synced_at": "2026-07-22T13:04:38.069Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01333267"
    },
    {
      "nct_id": "NCT00580788",
      "title": "One Week Parathyroid Hormone-related Protein (PTHrP) IV Dose Escalation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Osteoporosis",
        "Humoral Hypercalcemia of Malignancy",
        "Hyperparathyroidism"
      ],
      "interventions": [
        {
          "name": "PTHrP (1-36)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "24 Years to 35 Years"
      },
      "enrollment_count": 14,
      "start_date": "2008-01",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2016-02-11",
      "last_synced_at": "2026-07-22T13:04:38.069Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00580788"
    },
    {
      "nct_id": "NCT00896454",
      "title": "Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Hypercalcemia of Malignancy",
        "Colon Cancer",
        "Endocrine Cancer",
        "Head and Neck Cancer",
        "Kidney Cancer",
        "Lung Cancer",
        "Lymphoma",
        "Metastatic Cancer",
        "Multiple Myeloma",
        "Parathyroid Neoplasms",
        "Renal Cancer",
        "Thyroid Cancer",
        "Hodgkin's Lymphoma",
        "Non-Hodgkin's Lymphoma",
        "Non-Small Cell Lung Cancer"
      ],
      "interventions": [
        {
          "name": "denosumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Amgen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2009-11-16",
      "completion_date": "2013-08-21",
      "has_results": true,
      "last_update_posted_date": "2018-10-17",
      "last_synced_at": "2026-07-22T13:04:38.069Z",
      "location_count": 12,
      "location_summary": "Encinitas, California • New Haven, Connecticut • Salisbury, Maryland + 9 more",
      "locations": [
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Salisbury",
          "state": "Maryland"
        },
        {
          "city": "Dearborn",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00896454"
    },
    {
      "nct_id": "NCT00003884",
      "title": "Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hypercalcemia of Malignancy",
        "Lung Cancer",
        "Metastatic Cancer",
        "Pain",
        "Unspecified Adult Solid Tumor, Protocol Specific"
      ],
      "interventions": [
        {
          "name": "zoledronic acid",
          "type": "DRUG"
        },
        {
          "name": "quality-of-life assessment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Novartis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "1998-08",
      "completion_date": "2001-01",
      "has_results": false,
      "last_update_posted_date": "2013-02-21",
      "last_synced_at": "2026-07-22T13:04:38.069Z",
      "location_count": 55,
      "location_summary": "Birmingham, Alabama • Springdale, Arkansas • Gilroy, California + 48 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Springdale",
          "state": "Arkansas"
        },
        {
          "city": "Gilroy",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00003884"
    }
  ]
}