{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hyaline+Membrane+Disease",
    "query": {
      "condition": "Hyaline Membrane Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T01:40:47.482Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00433212",
      "title": "Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Insufficiency of Prematurity"
      ],
      "interventions": [
        {
          "name": "nCPAP",
          "type": "DEVICE"
        },
        {
          "name": "NIPPV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "28 Days",
        "sex": "ALL",
        "summary": "Up to 28 Days"
      },
      "enrollment_count": 1011,
      "start_date": "2007-04",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2014-12-05",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 14,
      "location_summary": "Washington D.C., District of Columbia • Boston, Massachusetts • Voorhees Township, New Jersey + 6 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Voorhees Township",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00433212"
    },
    {
      "nct_id": "NCT02294630",
      "title": "Aerosolized Surfactant in Neonatal RDS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "Surfactant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sood, Beena G., MD, MS",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 159,
      "start_date": "2014-12",
      "completion_date": "2020-07",
      "has_results": true,
      "last_update_posted_date": "2021-08-25",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02294630"
    },
    {
      "nct_id": "NCT07344714",
      "title": "Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn",
        "Respiratory Distress Syndrome in Premature Infant",
        "Transient Tachypnea of the Newborn",
        "Meconium Aspiration Syndrome",
        "Pneumonia Neonatal",
        "Hyaline Membrane Disease",
        "Pneumothorax",
        "Respiratory Distress Neonatal"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "32 Weeks",
        "maximum_age": "41 Weeks",
        "sex": "ALL",
        "summary": "32 Weeks to 41 Weeks"
      },
      "enrollment_count": 500,
      "start_date": "2026-03-11",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07344714"
    },
    {
      "nct_id": "NCT00599651",
      "title": "Randomized Controlled Trial of Surfactant Administration by Laryngeal Mask Airway (LMA)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "Surfactant administered via Laryngeal Mask Airway (LMA)",
          "type": "DEVICE"
        },
        {
          "name": "standard of care (nasal CPAP and supplemental oxygen)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 380,
      "start_date": "2005-06",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-05-07",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00599651"
    },
    {
      "nct_id": "NCT02112513",
      "title": "The Use of Maternal Serum Unconjugated Estriol for Monitoring the Prevention of Neonatal Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neonatal Respiratory Distress Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 160,
      "start_date": "2012-11",
      "completion_date": "2017-06-30",
      "has_results": false,
      "last_update_posted_date": "2019-02-28",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02112513"
    },
    {
      "nct_id": "NCT06140615",
      "title": "Lung Ultrasound - Prospective Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress of Newborn"
      ],
      "interventions": [
        {
          "name": "Ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 71,
      "start_date": "2023-12-11",
      "completion_date": "2026-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 2,
      "location_summary": "Minneapolis, Minnesota • Madison, Wisconsin",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06140615"
    },
    {
      "nct_id": "NCT03171129",
      "title": "ADINA vs. High Flow Nasal Cannula Comparison Study",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Neonatal"
      ],
      "interventions": [
        {
          "name": "Adaptive Dynamic Inspiratory Nasal Apparatus",
          "type": "DEVICE"
        },
        {
          "name": "High flow Nasal Canula",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "40 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 40 Weeks"
      },
      "enrollment_count": 40,
      "start_date": "2026-07",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03171129"
    },
    {
      "nct_id": "NCT07216053",
      "title": "Predictive Value of Lung Ultrasound for Respiratory Decompensation in Late Preterm Neonates",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pre-Term",
        "Respiratory Distress of Newborn",
        "Premature"
      ],
      "interventions": [
        {
          "name": "Point of care lung ultrasound",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Hackensack Meridian Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "34 Weeks",
        "maximum_age": "36 Weeks",
        "sex": "ALL",
        "summary": "34 Weeks to 36 Weeks"
      },
      "enrollment_count": 300,
      "start_date": "2025-11-06",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-05-22T01:40:47.482Z",
      "location_count": 1,
      "location_summary": "Hackensack, New Jersey",
      "locations": [
        {
          "city": "Hackensack",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07216053"
    }
  ]
}