{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hyperkeratosis%2C+Epidermolytic",
    "query": {
      "condition": "Hyperkeratosis, Epidermolytic"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:49:38.291Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04148651",
      "title": "The CO2RE® System for Vulvar Lichen Sclerosus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vulvar Lichen Sclerosus"
      ],
      "interventions": [
        {
          "name": "The CO2RE® System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Candela Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 14,
      "start_date": "2018-07-11",
      "completion_date": "2020-12-17",
      "has_results": true,
      "last_update_posted_date": "2022-03-22",
      "last_synced_at": "2026-05-22T07:49:38.291Z",
      "location_count": 4,
      "location_summary": "Jacksonville, Florida • Cincinnati, Ohio • South Burlington, Vermont",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "South Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04148651"
    },
    {
      "nct_id": "NCT06545695",
      "title": "Epidermal Growth Factor Receptor Inhibition for Keratinopathies",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Epidermolytic Ichthyosis",
        "Palmoplantar Keratoderma",
        "Pachyonychia Congenita"
      ],
      "interventions": [
        {
          "name": "Erlotinib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2027-07-01",
      "completion_date": "2031-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-05-22T07:49:38.291Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06545695"
    },
    {
      "nct_id": "NCT05853783",
      "title": "Evaluation of Oral Potentially Malignant Disorders (OPMDs) with STRATICYTE™",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mouth Diseases"
      ],
      "interventions": [
        {
          "name": "STRATICYTE™ Test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Proteocyte Diagnostics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2023-01-01",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2024-11-07",
      "last_synced_at": "2026-05-22T07:49:38.291Z",
      "location_count": 5,
      "location_summary": "Birmingham, Alabama • Loma Linda, California • Minneapolis, Minnesota + 1 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05853783"
    },
    {
      "nct_id": "NCT00074685",
      "title": "National Registry for Ichthyosis and Related Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Darier Disease",
        "Hailey-Hailey Disease",
        "Hyperkeratosis, Epidermolytic",
        "Ichthyosis",
        "Ichthyosis, Lamellar",
        "Ichthyosis, X-Linked",
        "Keratoderma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 610,
      "start_date": "1994-09",
      "completion_date": "2004-01",
      "has_results": false,
      "last_update_posted_date": "2022-09-28",
      "last_synced_at": "2026-05-22T07:49:38.291Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00074685"
    },
    {
      "nct_id": "NCT01270971",
      "title": "Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Onychomycosis of Toenails"
      ],
      "interventions": [
        {
          "name": "AN2690 Topical Solution, 5%",
          "type": "DRUG"
        },
        {
          "name": "Solution Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 594,
      "start_date": "2010-12-01",
      "completion_date": "2013-01-08",
      "has_results": true,
      "last_update_posted_date": "2019-02-22",
      "last_synced_at": "2026-05-22T07:49:38.291Z",
      "location_count": 27,
      "location_summary": "Tucson, Arizona • Hot Springs, Arkansas • Burbank, California + 23 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Hot Springs",
          "state": "Arkansas"
        },
        {
          "city": "Burbank",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01270971"
    },
    {
      "nct_id": "NCT01302119",
      "title": "Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Onychomycosis of Toenails"
      ],
      "interventions": [
        {
          "name": "AN2690 Topical Solution, 5%",
          "type": "DRUG"
        },
        {
          "name": "Solution Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 604,
      "start_date": "2011-02",
      "completion_date": "2013-02-20",
      "has_results": true,
      "last_update_posted_date": "2019-04-03",
      "last_synced_at": "2026-05-22T07:49:38.291Z",
      "location_count": 26,
      "location_summary": "Phoenix, Arizona • Novato, California • Oceanside, California + 22 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Novato",
          "state": "California"
        },
        {
          "city": "Oceanside",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01302119"
    },
    {
      "nct_id": "NCT03041038",
      "title": "The Efficacy and Safety of Secukinumab in Patients With Ichthyoses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ichthyosis",
        "Autosomal Recessive Congenital Ichthyosis",
        "Lamellar Ichthyosis",
        "Congenital Ichthyosiform Erythroderma",
        "Epidermolytic Ichthyosis",
        "Netherton Syndrome"
      ],
      "interventions": [
        {
          "name": "Secukinumab",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2016-12",
      "completion_date": "2020-08-31",
      "has_results": true,
      "last_update_posted_date": "2021-08-25",
      "last_synced_at": "2026-05-22T07:49:38.291Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • New York, New York",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03041038"
    }
  ]
}