{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hyperlipidemia%2C+Familial+Combined", "query": { "condition": "Hyperlipidemia, Familial Combined" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 11, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hyperlipidemia%2C+Familial+Combined&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-23T16:43:38.481Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00136981", "title": "Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia, Familial", "Hyperlipidemia" ], "interventions": [ { "name": "torcetrapib/atorvastatin", "type": "DRUG" }, { "name": "atorvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 800, "start_date": "2003-12", "completion_date": "2006-11", "has_results": false, "last_update_posted_date": "2015-04-22", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 7, "location_summary": "Hartford, Connecticut • Boston, Massachusetts • Minneapolis, Minnesota + 4 more", "locations": [ { "city": "Hartford", "state": "Connecticut" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "New York", "state": "New York" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00136981" }, { "nct_id": "NCT00345657", "title": "Efficacy Study of Extended-Release Niacin/Lovastatin Versus Usual Care", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hyperlipidemia", "Mixed Hyperlipidemia", "Dyslipidemia" ], "interventions": [ { "name": "Niacin Extended Release/Lovastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "In His Image", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2003-07", "completion_date": "2004-05", "has_results": false, "last_update_posted_date": "2006-06-28", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 1, "location_summary": "Tulsa, Oklahoma", "locations": [ { "city": "Tulsa", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT00345657" }, { "nct_id": "NCT00134238", "title": "Carotid B-mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrapib/Atorvastatin to Atorvastatin.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Mixed Hyperlipidemia" ], "interventions": [ { "name": "torcetrapib/atorvastatin", "type": "DRUG" }, { "name": "atorvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 755, "start_date": "2003-11", "completion_date": "2006-12", "has_results": false, "last_update_posted_date": "2012-02-17", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 40, "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 37 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Alhambra", "state": "California" }, { "city": "Encinitas", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00134238" }, { "nct_id": "NCT00754039", "title": "Study to Compare Welchol and TriCor to TriCor Alone in Patients With High Cholesterol", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypercholesterolemia", "Hyperlipidemia, Familial Combined" ], "interventions": [ { "name": "colesevelam HCl tablets and fenofibrate tablets", "type": "DRUG" }, { "name": "fenofibrate tablets and Welchol placebo tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "30 Years to 70 Years" }, "enrollment_count": 129, "start_date": "2003-02", "completion_date": "2004-03", "has_results": false, "last_update_posted_date": "2015-04-03", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 10, "location_summary": "Longwood, Florida • Ocala, Florida • Winterpark, Florida + 7 more", "locations": [ { "city": "Longwood", "state": "Florida" }, { "city": "Ocala", "state": "Florida" }, { "city": "Winterpark", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Lombard", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00754039" }, { "nct_id": "NCT00134485", "title": "Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia, Familial", "Hyperlipidemia" ], "interventions": [ { "name": "torcetrapib/atorvastatin", "type": "DRUG" }, { "name": "atorvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2005-03", "completion_date": "2006-03", "has_results": false, "last_update_posted_date": "2007-10-30", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 14, "location_summary": "San Diego, California • Washington D.C., District of Columbia • Lutz, Florida + 11 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Lutz", "state": "Florida" }, { "city": "Tampa", "state": "Florida" }, { "city": "Tripler AMC", "state": "Hawaii" } ], "official_url": "https://clinicaltrials.gov/study/NCT00134485" }, { "nct_id": "NCT03337308", "title": "A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hyperlipidemias" ], "interventions": [ { "name": "Bempedoic Acid + Ezetimibe Fixed-Dose Combination", "type": "COMBINATION_PRODUCT" }, { "name": "Bempedoic Acid", "type": "DRUG" }, { "name": "Ezetimibe", "type": "DRUG" }, { "name": "Placebos", "type": "DRUG" } ], "intervention_types": [ "COMBINATION_PRODUCT", "DRUG" ], "sponsor": "Esperion Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 382, "start_date": "2017-10-23", "completion_date": "2018-07-18", "has_results": true, "last_update_posted_date": "2020-04-08", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 5, "location_summary": "Ames, Iowa • Nashua, New Hampshire • Statesville, North Carolina + 2 more", "locations": [ { "city": "Ames", "state": "Iowa" }, { "city": "Nashua", "state": "New Hampshire" }, { "city": "Statesville", "state": "North Carolina" }, { "city": "Wilmington", "state": "North Carolina" }, { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03337308" }, { "nct_id": "NCT01594983", "title": "A Pilot Study to Assess the Efficacy and Safety of LCQ908 Alone and in Combination With Fenofibrate or Lovaza® in Patients With Severe Hypertriglyceridemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Non Familial Chylocmicronemia Syndrome (Non-FCS)" ], "interventions": [ { "name": "LCQ908", "type": "DRUG" }, { "name": "Fenofibrate", "type": "DRUG" }, { "name": "Fish Oil", "type": "DRUG" }, { "name": "Placebo of LCQ908", "type": "DRUG" }, { "name": "Placebo of fenofibrate", "type": "DRUG" }, { "name": "Placebo of fish oil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 58, "start_date": "2012-06", "completion_date": "2013-07", "has_results": false, "last_update_posted_date": "2020-12-17", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 28, "location_summary": "Muscle Shoals, Alabama • Glendale, Arizona • Encinitas, California + 23 more", "locations": [ { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Encinitas", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Brandon", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01594983" }, { "nct_id": "NCT00145431", "title": "Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Subjects With A Genetic Cholesterol Disorder.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hyperlipoproteinemia Type III" ], "interventions": [ { "name": "torcetrapib/atorvastatin", "type": "DRUG" }, { "name": "atorvastatin", "type": "DRUG" }, { "name": "fenofibrate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 41, "start_date": "2005-03", "completion_date": "2006-12", "has_results": false, "last_update_posted_date": "2012-02-17", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 22, "location_summary": "Anaheim, California • Huntington Beach, California • Orange, California + 18 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Pacific Palisades", "state": "California" }, { "city": "Studio City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00145431" }, { "nct_id": "NCT00134511", "title": "Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia, Familial" ], "interventions": [ { "name": "Torcetrapib/atorvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2005-03", "completion_date": "2005-11", "has_results": false, "last_update_posted_date": "2007-11-07", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00134511" }, { "nct_id": "NCT06005597", "title": "Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dyslipidemias", "Hypercholesterolemia", "Familial Hypercholesterolemia", "ASCVD", "High Cholesterol" ], "interventions": [ { "name": "Combination Therapy", "type": "COMBINATION_PRODUCT" }, { "name": "Monotherapy obicetrapib", "type": "DRUG" }, { "name": "Monotherapy ezetimibe", "type": "DRUG" }, { "name": "Combination Therapy placebo", "type": "OTHER" }, { "name": "Obicetrapib Placebo", "type": "OTHER" }, { "name": "Ezetimibe Placebo", "type": "OTHER" } ], "intervention_types": [ "COMBINATION_PRODUCT", "DRUG", "OTHER" ], "sponsor": "NewAmsterdam Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 407, "start_date": "2024-03-01", "completion_date": "2024-10-16", "has_results": true, "last_update_posted_date": "2025-10-08", "last_synced_at": "2026-07-23T16:43:38.481Z", "location_count": 45, "location_summary": "Gilbert, Arizona • Jacksonville, Florida • Port Orange, Florida + 37 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Port Orange", "state": "Florida" }, { "city": "Columbus", "state": "Georgia" }, { "city": "Gainesville", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06005597" } ] }