{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hyperopic+Astigmatism",
    "query": {
      "condition": "Hyperopic Astigmatism"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 2,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T12:49:22.173Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01893359",
      "title": "Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hyperopia",
        "Hyperopic Astigmatism"
      ],
      "interventions": [
        {
          "name": "riboflavin ophthalmic solution, 0% dextran",
          "type": "DRUG"
        },
        {
          "name": "UVA Irradiation (30 mW/cm2 for 2 minutes continuous UVA)",
          "type": "DEVICE"
        },
        {
          "name": "UVA Irradiation (30 mW/cm2 for 3 minutes pulsed UVA with an on/off cycle of 2 seconds UVA on/1 second UVA off)",
          "type": "DEVICE"
        },
        {
          "name": "Laser-assisted in situ keratomileusis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Glaukos Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2013-08",
      "completion_date": "2016-04",
      "has_results": true,
      "last_update_posted_date": "2021-04-26",
      "last_synced_at": "2026-07-22T12:49:22.173Z",
      "location_count": 5,
      "location_summary": "San Diego, California • Waltham, Massachusetts • Teaneck, New Jersey + 2 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Waltham",
          "state": "Massachusetts"
        },
        {
          "city": "Teaneck",
          "state": "New Jersey"
        },
        {
          "city": "Sioux Falls",
          "state": "South Dakota"
        },
        {
          "city": "McLean",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01893359"
    },
    {
      "nct_id": "NCT04805593",
      "title": "Clinical Investigation of the WaveLight® EX500 Excimer Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperopia",
        "Hyperopic Astigmatism"
      ],
      "interventions": [
        {
          "name": "WaveLight EX500 excimer laser system",
          "type": "DEVICE"
        },
        {
          "name": "LASIK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2021-04-28",
      "completion_date": "2023-05-02",
      "has_results": true,
      "last_update_posted_date": "2024-08-21",
      "last_synced_at": "2026-07-22T12:49:22.173Z",
      "location_count": 5,
      "location_summary": "Overland Park, Kansas • Kansas City, Missouri • Greensboro, North Carolina + 2 more",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Greensboro",
          "state": "North Carolina"
        },
        {
          "city": "West Fargo",
          "state": "North Dakota"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04805593"
    }
  ]
}