{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypertension%2C+Glaucoma%2C+Open-Angle&page=2",
    "query": {
      "condition": "Hypertension, Glaucoma, Open-Angle",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypertension%2C+Glaucoma%2C+Open-Angle&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-08T00:08:17.838Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05165290",
      "title": "Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Elevated Intraocular Pressure"
      ],
      "interventions": [
        {
          "name": "Latanoprost ophthalmic solution, 0.005%",
          "type": "DRUG"
        },
        {
          "name": "TC-002 latanoprost ophthalmic solution, 0.005%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "TearClear Corp",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2021-11-29",
      "completion_date": "2022-09",
      "has_results": false,
      "last_update_posted_date": "2022-05-25",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 20,
      "location_summary": "Garden Grove, California • Glendale, California • Mission Hills, California + 16 more",
      "locations": [
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "Mission Hills",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Petaluma",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05165290"
    },
    {
      "nct_id": "NCT03131167",
      "title": "Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Primary Open-angle Glaucoma (POAG)",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "SHP639 (n=60)",
          "type": "DRUG"
        },
        {
          "name": "Placebo Comparator (n=24)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Shire",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 63,
      "start_date": "2017-05-10",
      "completion_date": "2018-05-30",
      "has_results": true,
      "last_update_posted_date": "2021-06-08",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 1,
      "location_summary": "Lexington, Massachusetts",
      "locations": [
        {
          "city": "Lexington",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03131167"
    },
    {
      "nct_id": "NCT01495299",
      "title": "24-hour IOP Fluctuation Profile Recorded With SENSIMED Triggerfish in Primary Open-angle Glaucoma (POAG) Patients After Cataract Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Phacoemulsification with implantation of intraocular lens (CE-IOL) SENSIMED Triggerfish",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2011-12",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2019-08-21",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01495299"
    },
    {
      "nct_id": "NCT03267134",
      "title": "Hydrus Microstent for Refractory Open-Angle Glaucoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Open-angle Glaucoma"
      ],
      "interventions": [
        {
          "name": "Hydrus Microstent",
          "type": "DEVICE"
        },
        {
          "name": "Ophthalmic surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Ivantis, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 217,
      "start_date": "2017-08-01",
      "completion_date": "2022-12-16",
      "has_results": true,
      "last_update_posted_date": "2026-01-14",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 16,
      "location_summary": "Fayetteville, Arkansas • Sacramento, California • Fort Collins, Colorado + 13 more",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Ocala",
          "state": "Florida"
        },
        {
          "city": "Venice",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03267134"
    },
    {
      "nct_id": "NCT05506423",
      "title": "Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Open Angle Glaucoma"
      ],
      "interventions": [
        {
          "name": "CycloPen Cyclodialysis System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Iantrek, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2022-08-17",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 15,
      "location_summary": "Newport Beach, California • Cape Coral, Florida • DeLand, Florida + 12 more",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Cape Coral",
          "state": "Florida"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05506423"
    },
    {
      "nct_id": "NCT04285580",
      "title": "A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Open-Angle Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Bimatoprost SR",
          "type": "DRUG"
        },
        {
          "name": "LUMIGAN",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AbbVie",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2020-06-11",
      "completion_date": "2022-05-14",
      "has_results": true,
      "last_update_posted_date": "2023-06-08",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 6,
      "location_summary": "Dothan, Alabama • Newport Beach, California • Roswell, Georgia + 3 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Roswell",
          "state": "Georgia"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Cranberry Township",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04285580"
    },
    {
      "nct_id": "NCT06848946",
      "title": "Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Glaucoma, Open-angle",
        "Ocular Hypertension (OHT)",
        "Phacoemulsification Cataract Surgery"
      ],
      "interventions": [
        {
          "name": "iDose TR (travoprost intracameral implant) 75 µg in conjunction with cataract surgery",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Sham procedure in conjunction with cataract surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "PROCEDURE"
      ],
      "sponsor": "Glaukos Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2025-01-13",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 1,
      "location_summary": "Kenosha, Wisconsin",
      "locations": [
        {
          "city": "Kenosha",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06848946"
    },
    {
      "nct_id": "NCT01336569",
      "title": "Safety and Efficacy of Changing to DuoTrav in Patients Uncontrolled on Timolol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Travoprost 0.004%/timolol maleate 0.5% fixed combination",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2011-02",
      "completion_date": "2012-03",
      "has_results": true,
      "last_update_posted_date": "2013-07-08",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01336569"
    },
    {
      "nct_id": "NCT06152861",
      "title": "Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Open Angle Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Travoprost Ophthalmic Topical Cream low-dose",
          "type": "DRUG"
        },
        {
          "name": "Travoprost Ophthalmic Topical Cream mid-dose",
          "type": "DRUG"
        },
        {
          "name": "Travoprost Ophthalmic Topical Cream high-dose",
          "type": "DRUG"
        },
        {
          "name": "Timolol maleate ophthalmic solution, 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Travoprost Ophthalmic Solution, 0.004%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Glaukos Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2023-11-15",
      "completion_date": "2024-08",
      "has_results": false,
      "last_update_posted_date": "2023-12-06",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 1,
      "location_summary": "Newport Beach, California",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06152861"
    },
    {
      "nct_id": "NCT02599688",
      "title": "Open Label Extension of LipoLat-CS202",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Observation only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Peregrine Ophthalmic",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 18,
      "start_date": "2015-11",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2020-12-14",
      "last_synced_at": "2026-06-08T00:08:17.838Z",
      "location_count": 1,
      "location_summary": "Goose Creek, South Carolina",
      "locations": [
        {
          "city": "Goose Creek",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02599688"
    }
  ]
}