{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypertonia%2C+Muscle&page=2",
    "query": {
      "condition": "Hypertonia, Muscle",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypertonia%2C+Muscle&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T22:56:01.890Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03080454",
      "title": "The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Stroke",
        "Cerebrovascular Accident (CVA)",
        "Hemiparesis",
        "Spasticity as Sequela of Stroke",
        "Muscle Spasticity",
        "Upper Extremity Paralysis"
      ],
      "interventions": [
        {
          "name": "sham Doublestim",
          "type": "DEVICE"
        },
        {
          "name": "anodal Doublestim",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2016-09",
      "completion_date": "2018-03",
      "has_results": true,
      "last_update_posted_date": "2021-04-05",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 1,
      "location_summary": "Manhasset, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03080454"
    },
    {
      "nct_id": "NCT05311215",
      "title": "Phase II Study to Assess Safety, Pharmacokinetics and Efficacy of SL-1002 for Limb Spasticity",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Spasticity"
      ],
      "interventions": [
        {
          "name": "SL-1002",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Saol Therapeutics Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 32,
      "start_date": "2022-04-22",
      "completion_date": "2023-09",
      "has_results": false,
      "last_update_posted_date": "2023-09-06",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 2,
      "location_summary": "Houston, Texas • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05311215"
    },
    {
      "nct_id": "NCT01712087",
      "title": "Long-term Surveillance of the MedStream Programmable Infusion System",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spasticity"
      ],
      "interventions": [
        {
          "name": "MedStream Programmable Infusion System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Codman & Shurtleff",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2012-10-01",
      "completion_date": "2017-12-17",
      "has_results": false,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 2,
      "location_summary": "Worcester, Massachusetts • Houston, Texas",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01712087"
    },
    {
      "nct_id": "NCT00488839",
      "title": "IPX056 in Subjects With Established Spasticity Resulting From Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "IPX056 20 mg",
          "type": "DRUG"
        },
        {
          "name": "IPX056 40 mg",
          "type": "DRUG"
        },
        {
          "name": "Encapsulated Baclofen 20 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo Baclofen Tablet",
          "type": "DRUG"
        },
        {
          "name": "IPX056 10 mg",
          "type": "DRUG"
        },
        {
          "name": "IPX056 30 mg",
          "type": "DRUG"
        },
        {
          "name": "IPX056 35 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo IPX056 20 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo IPX056 40 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Impax Laboratories, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 173,
      "start_date": "2007-06",
      "completion_date": "2008-05",
      "has_results": false,
      "last_update_posted_date": "2019-11-06",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 20,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Colorado Springs, Colorado + 16 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00488839"
    },
    {
      "nct_id": "NCT00023075",
      "title": "Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Lateral Sclerosis",
        "Hereditary Spastic Paraplegia",
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 55,
      "start_date": "2001-08",
      "completion_date": "2003-08",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00023075"
    },
    {
      "nct_id": "NCT02903823",
      "title": "Intrathecal (IT) Baclofen Drug Distribution",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Muscle Spasticity"
      ],
      "interventions": [
        {
          "name": "Baclofen bolus injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 27,
      "start_date": "2016-04-22",
      "completion_date": "2019-02-01",
      "has_results": true,
      "last_update_posted_date": "2022-02-22",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02903823"
    },
    {
      "nct_id": "NCT05429736",
      "title": "Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Incomplete Spinal Cord Injury",
        "Spasticity, Muscle"
      ],
      "interventions": [
        {
          "name": "Motor Skill Training (MST)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Transcutaneous Spinal Stimulation (TSS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Shepherd Center, Atlanta GA",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 28,
      "start_date": "2022-03-01",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05429736"
    },
    {
      "nct_id": "NCT03319732",
      "title": "A Study to Evaluate the Long-term Safety of Arbaclofen Extended-Release Tablets for Patients With Spasticity Due to MS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Spasticity, Muscle"
      ],
      "interventions": [
        {
          "name": "Arbaclofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "RVL Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 323,
      "start_date": "2018-04-03",
      "completion_date": "2020-06-11",
      "has_results": true,
      "last_update_posted_date": "2022-08-09",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 1,
      "location_summary": "Fresno, California",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03319732"
    },
    {
      "nct_id": "NCT04203498",
      "title": "Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple Sclerosis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Multiple Sclerosis (MS)"
      ],
      "interventions": [
        {
          "name": "Nabiximols",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jazz Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 139,
      "start_date": "2020-10-01",
      "completion_date": "2023-02-28",
      "has_results": true,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 15,
      "location_summary": "Birmingham, Alabama • Port Charlotte, Florida • Tampa, Florida + 11 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Port Charlotte",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04203498"
    },
    {
      "nct_id": "NCT00565201",
      "title": "Evaluation of BOTOX® With Rehabilitation Therapy for the Treatment of Wrist and Hand Spasticity in Post-Stroke Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Botox and rehab",
          "type": "DRUG"
        },
        {
          "name": "Placebo and rehab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 25,
      "start_date": "2007-10",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2013-08-13",
      "last_synced_at": "2026-06-10T22:56:01.890Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00565201"
    }
  ]
}