{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypnotics+and+Sedatives",
    "query": {
      "condition": "Hypnotics and Sedatives"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 22,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypnotics+and+Sedatives&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T12:52:20.197Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01118273",
      "title": "Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Naproxen Sodium 440 mg (BAYH6689) / DPH 50mg",
          "type": "DRUG"
        },
        {
          "name": "Naproxen Sodium 440 mg (BAYH6689)",
          "type": "DRUG"
        },
        {
          "name": "Naproxen Sodium 220 mg (BAYH6689) / DPH 50mg",
          "type": "DRUG"
        },
        {
          "name": "Naproxen Sodium 220 mg (BAYH6689)",
          "type": "DRUG"
        },
        {
          "name": "DPH 50mg",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen 400 mg / Diphenhydramine citrate 76 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "16 Years to 45 Years"
      },
      "enrollment_count": 162,
      "start_date": "2008-01",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01118273"
    },
    {
      "nct_id": "NCT04284553",
      "title": "Optimizing Electronic Health Record Prompts With Behavioral Economics to Improve Prescribing for Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Benzodiazepine Sedative Adverse Reaction",
        "Anticholinergic Adverse Reaction",
        "Adverse Drug Event"
      ],
      "interventions": [
        {
          "name": "Order Entry",
          "type": "OTHER"
        },
        {
          "name": "Open Encounter",
          "type": "OTHER"
        },
        {
          "name": "Follow-up booster Alert",
          "type": "OTHER"
        },
        {
          "name": "Cold State outreach",
          "type": "OTHER"
        },
        {
          "name": "Simplified",
          "type": "OTHER"
        },
        {
          "name": "Sign-off alert",
          "type": "OTHER"
        },
        {
          "name": "Pre-commitment",
          "type": "OTHER"
        },
        {
          "name": "Different Risks",
          "type": "OTHER"
        },
        {
          "name": "Standard Epic Basic Alert",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Alert",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 216,
      "start_date": "2020-10-13",
      "completion_date": "2022-08-31",
      "has_results": true,
      "last_update_posted_date": "2024-11-07",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Braintree, Massachusetts",
      "locations": [
        {
          "city": "Braintree",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04284553"
    },
    {
      "nct_id": "NCT00919698",
      "title": "Delirium in Mechanically Ventilated Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Delirium"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2010-06",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2014-12-03",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00919698"
    },
    {
      "nct_id": "NCT03511209",
      "title": "Discontinuation of Hypnotics in Older Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia"
      ],
      "interventions": [
        {
          "name": "CBTI plus taper method A",
          "type": "BEHAVIORAL"
        },
        {
          "name": "CBTI plus taper method B",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2018-12-10",
      "completion_date": "2023-11-27",
      "has_results": true,
      "last_update_posted_date": "2024-11-14",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "West Los Angeles, California",
      "locations": [
        {
          "city": "West Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03511209"
    },
    {
      "nct_id": "NCT02577250",
      "title": "Ketamine Infusions for PTSD and Treatment-Resistant Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Depressive Disorder, Treatment-Resistant",
        "Stress Disorders, Post-Traumatic"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Minneapolis Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 20,
      "start_date": "2015-05",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2019-05-14",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02577250"
    },
    {
      "nct_id": "NCT05027438",
      "title": "Reducing Use of Sleep Medications Assisted by a Digital Insomnia Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Deprescribing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2022-09-22",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-04-11",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05027438"
    },
    {
      "nct_id": "NCT05538065",
      "title": "NUDGE-EHR Replication Trial at Mass General Brigham",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Benzodiazepine Sedative Adverse Reaction",
        "Anticholinergic Adverse Reaction",
        "Adverse Drug Event"
      ],
      "interventions": [
        {
          "name": "Follow-up booster Alert",
          "type": "OTHER"
        },
        {
          "name": "Pre-commitment",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Alert",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 201,
      "start_date": "2022-11-10",
      "completion_date": "2024-06-15",
      "has_results": true,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05538065"
    },
    {
      "nct_id": "NCT06403852",
      "title": "Investigating Near-Threshold Perception During Anesthetic Sedation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Propofol",
        "Anesthesia",
        "fMRI"
      ],
      "interventions": [
        {
          "name": "Functional Magnetic Resonance Imaging (fMRI) with propofol",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 36,
      "start_date": "2024-05-10",
      "completion_date": "2025-10-03",
      "has_results": false,
      "last_update_posted_date": "2025-11-13",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06403852"
    },
    {
      "nct_id": "NCT04818827",
      "title": "Ketamine Infusion as Sedative Analgesic in Severe ARDS",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intensive Care Unit Syndrome",
        "Mechanical Ventilation Complication",
        "Sedatives and Hypnotics Causing Adverse Effects in Therapeutic Use",
        "Delirium"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Interfaith Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 124,
      "start_date": "2020-02-01",
      "completion_date": "2021-02-14",
      "has_results": false,
      "last_update_posted_date": "2021-03-26",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04818827"
    },
    {
      "nct_id": "NCT00095251",
      "title": "MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Delirium"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Lorazepam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2004-08",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2018-09-11",
      "last_synced_at": "2026-06-27T12:52:20.197Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00095251"
    }
  ]
}