{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypoplastic+Left+Heart",
    "query": {
      "condition": "Hypoplastic Left Heart"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 46,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypoplastic+Left+Heart&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:38:59.256Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01736956",
      "title": "Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis",
        "Hypoplastic Left Heart Syndrome"
      ],
      "interventions": [
        {
          "name": "Fetal Aortic Valvuloplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "16 Years and older · Female only"
      },
      "enrollment_count": 9,
      "start_date": "2012-10",
      "completion_date": "2022-10",
      "has_results": false,
      "last_update_posted_date": "2023-01-09",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01736956"
    },
    {
      "nct_id": "NCT03079401",
      "title": "Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hypoplastic Left Heart Syndrome",
        "Atrioventricular Canal"
      ],
      "interventions": [
        {
          "name": "MPC; rexlemestrocel-L",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "Up to 5 Years"
      },
      "enrollment_count": 19,
      "start_date": "2017-11-27",
      "completion_date": "2024-01",
      "has_results": false,
      "last_update_posted_date": "2023-04-21",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03079401"
    },
    {
      "nct_id": "NCT01135485",
      "title": "Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 33,
      "start_date": "2010-03",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-08-02",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01135485"
    },
    {
      "nct_id": "NCT01883076",
      "title": "Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoplastic Left Heart Syndrome"
      ],
      "interventions": [
        {
          "name": "autologous cell-based delivery",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Timothy J Nelson, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Months",
        "sex": "ALL",
        "summary": "Up to 18 Months"
      },
      "enrollment_count": 30,
      "start_date": "2013-05-15",
      "completion_date": "2021-04-28",
      "has_results": false,
      "last_update_posted_date": "2022-04-29",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 6,
      "location_summary": "Los Angeles, California • Aurora, Colorado • Minneapolis, Minnesota + 3 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01883076"
    },
    {
      "nct_id": "NCT02135081",
      "title": "Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Single Ventricle Defect"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Months",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "4 Months to 10 Years"
      },
      "enrollment_count": 260,
      "start_date": "2008-12",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2018-03-19",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02135081"
    },
    {
      "nct_id": "NCT02852031",
      "title": "National Collaborative to Improve Care of Children With Complex Congenital Heart Disease",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoplastic Left Heart Syndrome (HLHS)"
      ],
      "interventions": [
        {
          "name": "Collaborative Learning Network",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "15 Months",
        "sex": "ALL",
        "summary": "Up to 15 Months"
      },
      "enrollment_count": 1000,
      "start_date": "2016-05",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2025-06-19",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 61,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 53 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02852031"
    },
    {
      "nct_id": "NCT01169519",
      "title": "Sildenafil in Single Ventricle Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Disease"
      ],
      "interventions": [
        {
          "name": "Sildenafil by injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "120 Months",
        "sex": "ALL",
        "summary": "3 Months to 120 Months"
      },
      "enrollment_count": 21,
      "start_date": "2011-04",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2013-12-05",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01169519"
    },
    {
      "nct_id": "NCT02462434",
      "title": "Impact of Early Intervention on Maternal Stress in Mothers of Fetuses Diagnosed With Single Ventricle Physiology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Defects, Congenital",
        "Hypoplastic Left Heart Syndrome",
        "Single Ventricle Defect",
        "Stress, Psychological"
      ],
      "interventions": [
        {
          "name": "Early palliative care team consultation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2013-04",
      "completion_date": "2016-11-15",
      "has_results": false,
      "last_update_posted_date": "2017-04-18",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02462434"
    },
    {
      "nct_id": "NCT05386173",
      "title": "Effect of Fetal Aortic Valvuloplasty on Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease",
        "Aortic Valve Stenosis",
        "Fetal Cardiac Disorder",
        "Hypoplastic Left Heart Syndrome"
      ],
      "interventions": [
        {
          "name": "Fetal aortic balloon dilatation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Queen Silvia Children's Hospital, Gothenburg, Sweden",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "31 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 31 Weeks"
      },
      "enrollment_count": 200,
      "start_date": "2021-01-01",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-21",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Columbus, Ohio",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05386173"
    },
    {
      "nct_id": "NCT06469918",
      "title": "The Co-Op @ HeartWorks",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "HeartWorks, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "0 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2024-01-24",
      "completion_date": "2050-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-05-22T05:38:59.256Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06469918"
    }
  ]
}