{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypoplastic+Right+Heart+Syndrome",
    "query": {
      "condition": "Hypoplastic Right Heart Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:47:52.181Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02135081",
      "title": "Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Single Ventricle Defect"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Months",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "4 Months to 10 Years"
      },
      "enrollment_count": 260,
      "start_date": "2008-12",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2018-03-19",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02135081"
    },
    {
      "nct_id": "NCT01169519",
      "title": "Sildenafil in Single Ventricle Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Disease"
      ],
      "interventions": [
        {
          "name": "Sildenafil by injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "120 Months",
        "sex": "ALL",
        "summary": "3 Months to 120 Months"
      },
      "enrollment_count": 21,
      "start_date": "2011-04",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2013-12-05",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01169519"
    },
    {
      "nct_id": "NCT04907526",
      "title": "Intramyocardial Injection of Autologous UCB-MNC During Fontan Surgery for SRV Dependent CHD",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Congenital Heart Disease, SRV Dependent"
      ],
      "interventions": [
        {
          "name": "Autologous mononuclear cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Timothy J Nelson, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "2 Years to 5 Years"
      },
      "enrollment_count": 30,
      "start_date": "2021-06-01",
      "completion_date": "2025-08-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 6,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 3 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04907526"
    },
    {
      "nct_id": "NCT03779711",
      "title": "Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypoplastic Left Heart Syndrome"
      ],
      "interventions": [
        {
          "name": "Autologous (self) mononuclear cells derived from umbilical cord blood",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Stage II Surgical repair",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Timothy J Nelson, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "Up to 12 Months"
      },
      "enrollment_count": 95,
      "start_date": "2019-06-06",
      "completion_date": "2026-02",
      "has_results": true,
      "last_update_posted_date": "2025-07-08",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 8,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 5 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03779711"
    },
    {
      "nct_id": "NCT02080637",
      "title": "Ambrisentan in Single Ventricle",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypoplastic Left Heart Syndrome",
        "Hypoplastic Right-sided Heart Complex"
      ],
      "interventions": [
        {
          "name": "Ambrisentan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Kevin Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Months",
        "maximum_age": "120 Months",
        "sex": "ALL",
        "summary": "24 Months to 120 Months"
      },
      "enrollment_count": 16,
      "start_date": "2015-07",
      "completion_date": "2017-08-20",
      "has_results": true,
      "last_update_posted_date": "2019-09-12",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02080637"
    },
    {
      "nct_id": "NCT01656941",
      "title": "Genetic Determinants of Congenital Heart Disease Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease",
        "Hypoplastic Left Heart Syndrome",
        "Hypoplastic Right Heart Syndrome",
        "d-Transposition of the Great Arteries"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "Up to 30 Days"
      },
      "enrollment_count": 250,
      "start_date": "2011-03",
      "completion_date": "2017-03-16",
      "has_results": false,
      "last_update_posted_date": "2021-08-10",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 4,
      "location_summary": "Atlanta, Georgia • Ann Arbor, Michigan • Charleston, South Carolina + 1 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01656941"
    },
    {
      "nct_id": "NCT04702373",
      "title": "Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "passive range of motion exercise therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Carelon Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "35 Days",
        "sex": "ALL",
        "summary": "Up to 35 Days"
      },
      "enrollment_count": 144,
      "start_date": "2021-02-23",
      "completion_date": "2024-12-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 9,
      "location_summary": "Atlanta, Georgia • Indianapolis, Indiana • Boston, Massachusetts + 6 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04702373"
    },
    {
      "nct_id": "NCT04452188",
      "title": "Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoplastic Left Heart Syndrome",
        "Total Anomalous Pulmonary Venous Return",
        "Truncus Arteriosus",
        "Pulmonary Atresia With Ventricular Septal Defect",
        "Transposition of the Great Arteries",
        "Double Outlet Right Ventricle, Subpulmonary VSD",
        "Tetralogy of Fallot",
        "Double Outlet Right Ventricle With Subaortic Ventricular Septal Defect and Pulmonary Stenosis",
        "Cardiopulmonary Bypass"
      ],
      "interventions": [
        {
          "name": "Normoxia (with controlled re-oxygenation)",
          "type": "OTHER"
        },
        {
          "name": "Standard of care ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "29 Days",
        "sex": "ALL",
        "summary": "Up to 29 Days"
      },
      "enrollment_count": 29,
      "start_date": "2021-01-18",
      "completion_date": "2023-04-20",
      "has_results": true,
      "last_update_posted_date": "2024-06-18",
      "last_synced_at": "2026-05-22T07:47:52.181Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04452188"
    }
  ]
}