{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypotonia",
    "query": {
      "condition": "Hypotonia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 21,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypotonia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:07:50.121Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02425449",
      "title": "Fade Upon TOF Stimulation Induced by Succinylcholine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Muscle Relaxants"
      ],
      "interventions": [
        {
          "name": "Succinylcholine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Toledo Health Science Campus",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 19,
      "start_date": "2015-04",
      "completion_date": "2017-01-04",
      "has_results": true,
      "last_update_posted_date": "2018-01-02",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "Toledo, Ohio",
      "locations": [
        {
          "city": "Toledo",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02425449"
    },
    {
      "nct_id": "NCT06614582",
      "title": "Long-term Evaluation of Nasopharyngeal Airway in Hypotonia",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypotonia, Muscle",
        "Obstructive Sleep Apnea",
        "Nasal Airway Obstruction"
      ],
      "interventions": [
        {
          "name": "Self-Supporting Nasopharyngeal Airway (ssNPA)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "23 Years",
        "sex": "ALL",
        "summary": "3 Years to 23 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-10-23",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2025-12-02",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06614582"
    },
    {
      "nct_id": "NCT00208091",
      "title": "Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Focal Dystonia"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin, type B",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "25 Years to 69 Years"
      },
      "enrollment_count": 16,
      "start_date": "2003-04",
      "completion_date": "2008-05",
      "has_results": true,
      "last_update_posted_date": "2014-05-09",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00208091"
    },
    {
      "nct_id": "NCT02625155",
      "title": "Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Target Drug-related Adverse Events"
      ],
      "interventions": [
        {
          "name": "Urine diagnostic testing as SOC, drug regimen changes per SOC",
          "type": "OTHER"
        },
        {
          "name": "Urine diagnostic testing with selective PGx testing, drug regimen changes based on PGx test results",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "InSource Diagnostics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 14000,
      "start_date": "2015-12",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2018-02-28",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "Tazewell, Tennessee",
      "locations": [
        {
          "city": "Tazewell",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02625155"
    },
    {
      "nct_id": "NCT03701568",
      "title": "A RETROspective Study of Patients With TK2d",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Thymidine Kinase 2 (TK2)"
      ],
      "interventions": [
        {
          "name": "dC/dT",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Zogenix MDS, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 38,
      "start_date": "2018-11-19",
      "completion_date": "2019-05-31",
      "has_results": false,
      "last_update_posted_date": "2023-09-01",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03701568"
    },
    {
      "nct_id": "NCT02157545",
      "title": "The Dose-Response Relationship of Rocuronium in Patients Taking Pyridostigmine",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Muscle Relaxants"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Shashi Bhatt, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2014-03",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-07-19",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "Toledo, Ohio",
      "locations": [
        {
          "city": "Toledo",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02157545"
    },
    {
      "nct_id": "NCT05440058",
      "title": "BIS Monitoring in Relation to Muscle Relaxant Administration",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiovascular Surgery",
        "Bispectral Index",
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Bispectral Index (BIS) monitoring system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2022-08-26",
      "completion_date": "2022-09-20",
      "has_results": false,
      "last_update_posted_date": "2023-10-13",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05440058"
    },
    {
      "nct_id": "NCT02584413",
      "title": "Hypotonia and Neurofibromatosis Type 1 (NF1) Glioma",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurofibromatosis Type 1"
      ],
      "interventions": [
        {
          "name": "Magnetic resonance imaging",
          "type": "DEVICE"
        },
        {
          "name": "Gadolinium contrast",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "7 Years",
        "sex": "ALL",
        "summary": "1 Year to 7 Years"
      },
      "enrollment_count": 29,
      "start_date": "2013-04-16",
      "completion_date": "2019-02-07",
      "has_results": false,
      "last_update_posted_date": "2019-09-03",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02584413"
    },
    {
      "nct_id": "NCT02057705",
      "title": "Prospective, Longitudinal Study of the Natural History and Functional Status of Patients With Myotubular Myopathy (MTM)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myotubular Myopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Valerion Therapeutics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 48,
      "start_date": "2014-02",
      "completion_date": "2017-06-26",
      "has_results": false,
      "last_update_posted_date": "2018-06-07",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02057705"
    },
    {
      "nct_id": "NCT03116997",
      "title": "Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Neostigmine+glycopyrrolate",
          "type": "DRUG"
        },
        {
          "name": "Sugammadex",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 201,
      "start_date": "2017-04-07",
      "completion_date": "2022-03-03",
      "has_results": true,
      "last_update_posted_date": "2025-05-18",
      "last_synced_at": "2026-05-22T05:07:50.121Z",
      "location_count": 4,
      "location_summary": "Basking Ridge, New Jersey • Commack, New York • Harrison, New York + 1 more",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        },
        {
          "city": "Commack",
          "state": "New York"
        },
        {
          "city": "Harrison",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03116997"
    }
  ]
}