{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypoxia-Ischemia%2C+Brain&page=3",
    "query": {
      "condition": "Hypoxia-Ischemia, Brain",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 90,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypoxia-Ischemia%2C+Brain&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Hypoxia-Ischemia%2C+Brain&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T23:34:30.875Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02612155",
      "title": "A Multi-site Study of Autologous Cord Blood Cells for Hypoxic Ischemic Encephalopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Moderate or Severe Hypoxic-ischemic Encephalopathy in Newborns"
      ],
      "interventions": [
        {
          "name": "Infusion of autologous cord blood",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Michael Cotten",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Hours",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "0 Hours to 6 Hours"
      },
      "enrollment_count": 35,
      "start_date": "2017-03-30",
      "completion_date": "2019-08-05",
      "has_results": true,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02612155"
    },
    {
      "nct_id": "NCT02793999",
      "title": "Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic Ischemic Brain Injury",
        "Neonatal Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Near-Infrared Spectroscopy (NIRS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 125,
      "start_date": "2015-05",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2025-12-10",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02793999"
    },
    {
      "nct_id": "NCT07493096",
      "title": "Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neurodevelopmental Disorders",
        "Neurodevelopmental Disorders (NDD)",
        "Neurodevelopmental Disorders and Developmental Abnormalities",
        "Developmental Delay (Disorder)",
        "Cerebral Palsy (CP)",
        "Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment",
        "Cerebral Palsy Infantile",
        "Cerebral Palsy Spastic Hemiplegic",
        "Cerebral Palsy, Dyskinetic",
        "Autism Spectrum Disorder",
        "Autism Spectrum Disorder (ASD",
        "Hypoxic Ischemic Encephalopathy",
        "Hypoxic Ischemic Encephalopathy (HIE)",
        "Traumatic Brain Injury (TBI)",
        "Sensory Processing Disorder",
        "Chromosomal Abnormalities",
        "Genetic Disorders",
        "Down Syndrome (Trisomy 21)",
        "Fragile X Syndrome (FXS)",
        "RETT Syndrome With Proven MECP2 Mutation",
        "Williams Syndrome",
        "22q11.2 Deletion Syndrome",
        "Sensorimotor Integration"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Healing Hope International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "4 Years to 12 Years"
      },
      "enrollment_count": 100,
      "start_date": "2026-03-01",
      "completion_date": "2036-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-25",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 1,
      "location_summary": "The Woodlands, Texas",
      "locations": [
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07493096"
    },
    {
      "nct_id": "NCT03071861",
      "title": "Mild Encephalopathy in the Newborn Treated With Darbepoetin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Neonatal Encephalopathy",
        "Hypoxic-Ischemic Encephalopathy Mild"
      ],
      "interventions": [
        {
          "name": "Darbepoetin Alfa",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 28,
      "start_date": "2017-12-01",
      "completion_date": "2022-09-01",
      "has_results": true,
      "last_update_posted_date": "2023-12-21",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03071861"
    },
    {
      "nct_id": "NCT04337697",
      "title": "Neonatal Seizure Registry - Developmental Functional EValuation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neonatal Seizure",
        "Hypoxic-Ischemic Encephalopathy",
        "Stroke",
        "Intracranial Hemorrhages",
        "Epilepsy",
        "Cerebral Palsy",
        "Intellectual Disability"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "2 Years to 8 Years"
      },
      "enrollment_count": 188,
      "start_date": "2020-03-15",
      "completion_date": "2025-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 9,
      "location_summary": "San Francisco, California • Stanford, California • Washington D.C., District of Columbia + 5 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04337697"
    },
    {
      "nct_id": "NCT01128673",
      "title": "MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(HIE)",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "mRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Week",
        "sex": "ALL",
        "summary": "Up to 1 Week"
      },
      "enrollment_count": 0,
      "start_date": "2010-05",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-03",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01128673"
    },
    {
      "nct_id": "NCT07197918",
      "title": "Identification of Brain Injury Using Portable MRI",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiac Arrest (CA)",
        "Hypoxic-Ischemic Brain Injury"
      ],
      "interventions": [
        {
          "name": "portable MRI scanner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-12-02",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07197918"
    },
    {
      "nct_id": "NCT01936246",
      "title": "Protein Supplementation in Infants With Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perinatal Stroke",
        "Hypoxic-ischemic Encephalopathy",
        "White Matter Injury"
      ],
      "interventions": [
        {
          "name": "Increased protein",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Days",
        "maximum_age": "3 Weeks",
        "sex": "ALL",
        "summary": "2 Days to 3 Weeks"
      },
      "enrollment_count": 24,
      "start_date": "2012-08",
      "completion_date": "2016-02",
      "has_results": false,
      "last_update_posted_date": "2017-07-06",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01936246"
    },
    {
      "nct_id": "NCT04621279",
      "title": "Cool Prime Comparative Effectiveness Study for Mild HIE",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mild Hypoxic Ischemic Encephalopathy of Newborn"
      ],
      "interventions": [
        {
          "name": "Normothermia",
          "type": "PROCEDURE"
        },
        {
          "name": "Whole body therapeutic hypothermia",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "36 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "36 Weeks and older"
      },
      "enrollment_count": 460,
      "start_date": "2023-07-19",
      "completion_date": "2029-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04621279"
    },
    {
      "nct_id": "NCT05376267",
      "title": "Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Arrest, Out-Of-Hospital",
        "Hypothermia, Induced",
        "Hypoxia-Ischemia, Brain"
      ],
      "interventions": [
        {
          "name": "Therapeutic Hypothermia",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Days",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Days to 17 Years"
      },
      "enrollment_count": 900,
      "start_date": "2022-08-05",
      "completion_date": "2028-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-08",
      "last_synced_at": "2026-10-09T23:34:30.875Z",
      "location_count": 52,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 44 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05376267"
    }
  ]
}