{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=IBS",
    "query": {
      "condition": "IBS"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 243,
    "total_pages": 25,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=IBS&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T23:12:23.263Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00219531",
      "title": "Effect of Menstrual Cycle on Central Nervous System (CNS) Processing of Gut Stimuli in Irritable Bowel Syndrome (IBS) and Control",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Irritable Bowel Syndrome"
      ],
      "interventions": [
        {
          "name": "perception of rectal balloon distention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 48,
      "start_date": "1999-03",
      "completion_date": "2015-02",
      "has_results": false,
      "last_update_posted_date": "2017-11-29",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00219531"
    },
    {
      "nct_id": "NCT06657001",
      "title": "Enabling Microbiomics- Driven Personalized Nutrition",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Inflammatory Bowel Disease (IBD)",
        "Irritable Bowel Syndrome (IBS)",
        "Celiac Disease",
        "Diarrhea",
        "Constipation",
        "Microbiome",
        "Crohn's Disease",
        "UC - Ulcerative Colitis",
        "Microscopic Colitis",
        "Functional Dyspepsia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4001,
      "start_date": "2025-03-28",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06657001"
    },
    {
      "nct_id": "NCT04256551",
      "title": "Effects of a Novel Machine Learning Mobile App on Diet Adherence in Individuals Following the Low Fodmap Diet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "IBS - Irritable Bowel Syndrome"
      ],
      "interventions": [
        {
          "name": "Heali mobile application + Registered Dietitian",
          "type": "OTHER"
        },
        {
          "name": "Heali mobile application",
          "type": "OTHER"
        },
        {
          "name": "Standard Dietary Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 58,
      "start_date": "2020-01-23",
      "completion_date": "2020-06-01",
      "has_results": false,
      "last_update_posted_date": "2020-07-08",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04256551"
    },
    {
      "nct_id": "NCT02419963",
      "title": "Analyzing IBS to Identify Biomarkers and Microbiome Signatures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diarrhoea Predominant Irritable Bowel Syndrome",
        "IBS"
      ],
      "interventions": [
        {
          "name": "endoscopy for tissue biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood Sample",
          "type": "OTHER"
        },
        {
          "name": "Stool Sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 26,
      "start_date": "2015-05",
      "completion_date": "2016-12-12",
      "has_results": false,
      "last_update_posted_date": "2017-07-07",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02419963"
    },
    {
      "nct_id": "NCT06760533",
      "title": "Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "IBS - Irritable Bowel Syndrome"
      ],
      "interventions": [
        {
          "name": "Psilocybin 25 mg",
          "type": "DRUG"
        },
        {
          "name": "Psychotherapy Treatment Session",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Niacin 100 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2026-08",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06760533"
    },
    {
      "nct_id": "NCT00618904",
      "title": "Efficacy of Probiotic Bacteria in Subjects With IBS or Functional Diarrhea/ Bloating",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Probiotics - Lactobacillus and bifidobacterium",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 56,
      "start_date": "2005-12",
      "completion_date": "2007-09",
      "has_results": false,
      "last_update_posted_date": "2013-07-09",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00618904"
    },
    {
      "nct_id": "NCT00616200",
      "title": "Effects of a Very Low Carbohydrate Diet on Symptoms of Irritable Bowel Syndrome (IBS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diarrhea Predominant Irritable Bowel Syndrome"
      ],
      "interventions": [
        {
          "name": "Very low carbohydrate diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 17,
      "start_date": "2009-08",
      "completion_date": "2010-05",
      "has_results": true,
      "last_update_posted_date": "2017-10-16",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00616200"
    },
    {
      "nct_id": "NCT02559206",
      "title": "Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Irritable Bowel Syndrome With Constipation"
      ],
      "interventions": [
        {
          "name": "Linaclotide",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ironwood Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 759,
      "start_date": "2015-10-22",
      "completion_date": "2016-09-30",
      "has_results": true,
      "last_update_posted_date": "2020-04-24",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 71,
      "location_summary": "Huntsville, Alabama • Phoenix, Arizona • Tucson, Arizona + 61 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "North Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Anaheim",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02559206"
    },
    {
      "nct_id": "NCT05579444",
      "title": "Systems Biology of Gastrointestinal and Related Diseases",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ulcerative Colitis",
        "Crohn Disease",
        "Obesity",
        "Colon Polyp",
        "Eosinophilic Esophagitis",
        "GERD",
        "Gastro Esophageal Reflux",
        "Barrett Esophagus",
        "Esophageal Cancer",
        "Gastritis",
        "Gastric Ulcer",
        "Duodenal Ulcer",
        "Intestinal Metaplasia",
        "Gastric Cancer",
        "Lymphocytic Colitis",
        "Microscopic Colitis",
        "Celiac Sprue",
        "IBS",
        "Irritable Bowel Syndrome",
        "SIBO",
        "NAFLD",
        "Gallstone Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Viome",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2022-11-11",
      "completion_date": "2023-11-29",
      "has_results": false,
      "last_update_posted_date": "2023-12-15",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "Bothell, Washington",
      "locations": [
        {
          "city": "Bothell",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05579444"
    },
    {
      "nct_id": "NCT02186743",
      "title": "Irritable Bowel Syndrome and Food Sensitivity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Irritable Bowel Syndrome"
      ],
      "interventions": [
        {
          "name": "Personalized Dietary Advice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 58,
      "start_date": "2014-07",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2017-10-18",
      "last_synced_at": "2026-05-21T23:12:23.263Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02186743"
    }
  ]
}