{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=IGF1R&page=2", "query": { "condition": "IGF1R", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=IGF1R&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T04:50:57.810Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00924989", "title": "A Study of OSI-906 in Patients With Locally Advanced or Metastatic Adrenocortical Carcinoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Adrenocortical Carcinoma" ], "interventions": [ { "name": "OSI-906", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Astellas Pharma Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 139, "start_date": "2009-12-01", "completion_date": "2012-10-08", "has_results": false, "last_update_posted_date": "2024-11-20", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 14, "location_summary": "Scottsdale, Arizona • Los Angeles, California • Aurora, Colorado + 10 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00924989" }, { "nct_id": "NCT06112340", "title": "Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Thyroid Eye Disease", "Graves Orbitopathy", "Endocrine System Diseases", "Eye Diseases", "Thyroid Associated Ophthalmopathy", "Graves Ophthalmopathy", "Thyroid Diseases", "Orbital Diseases", "Proptosis", "IGF1R", "Exophthalmos", "Hashimoto" ], "interventions": [ { "name": "linsitinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sling Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 75, "start_date": "2023-10-11", "completion_date": "2026-06", "has_results": false, "last_update_posted_date": "2025-02-25", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 2, "location_summary": "Miami, Florida • Morgantown, West Virginia", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06112340" }, { "nct_id": "NCT00778817", "title": "IMC-A12 With Mitotane vs Mitotane Alone in Recurrent, Metastatic, or Primary ACC That Cannot Be Removed by Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Recurrent Adrenocortical Carcinoma", "Stage III Adrenocortical Carcinoma", "Stage IV Adrenocortical Carcinoma" ], "interventions": [ { "name": "IMC-A12", "type": "BIOLOGICAL" }, { "name": "mitotane", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2008-12", "completion_date": "2014-03", "has_results": true, "last_update_posted_date": "2014-04-29", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 8, "location_summary": "Los Angeles, California • Chicago, Illinois • Decatur, Illinois + 3 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Decatur", "state": "Illinois" }, { "city": "Springfield", "state": "Illinois" }, { "city": "Springfield", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00778817" }, { "nct_id": "NCT02103283", "title": "A Phase 1, Open-Label Study of Teprotumumab in Patients With Diabetic Macular Edema (DME)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diabetic Macular Edema" ], "interventions": [ { "name": "Teprotumumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 5, "start_date": "2014-10", "completion_date": "2016-08", "has_results": false, "last_update_posted_date": "2025-06-25", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 3, "location_summary": "Beverly Hills, California • St. Petersburg, Florida • Omaha, Nebraska", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "St. Petersburg", "state": "Florida" }, { "city": "Omaha", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT02103283" }, { "nct_id": "NCT02507583", "title": "Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Malignant Glioma", "Neoplasms" ], "interventions": [ { "name": "IGF-1R/AS ODN; Surgery with tissue harvest and implantation 20 diffusion chambers in the rectus sheath with IGF-1R/AS ODN within 24 hours of craniotomy, implanted for 48 hours.", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "david andrews", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2015-09-01", "completion_date": "2020-08-17", "has_results": false, "last_update_posted_date": "2025-05-07", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02507583" }, { "nct_id": "NCT00005105", "title": "Genetic Study of Insulin-Like Growth Factor-I Receptor Mutations in Patients With Intrauterine Growth Retardation", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Intrauterine Growth Retardation" ], "interventions": [], "intervention_types": [], "sponsor": "National Center for Research Resources (NCRR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Months", "maximum_age": "18 Years", "sex": "ALL", "summary": "18 Months to 18 Years" }, "enrollment_count": 75, "start_date": "1997-01", "completion_date": null, "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 5, "location_summary": "Atlanta, Georgia • Indianapolis, Indiana • New Hyde Park, New York + 2 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "New Hyde Park", "state": "New York" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00005105" }, { "nct_id": "NCT00778167", "title": "Erlotinib Hydrochloride With or Without Cixutumumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Recurrent Non-small Cell Lung Cancer", "Stage IIIA Non-small Cell Lung Cancer", "Stage IIIB Non-small Cell Lung Cancer", "Stage IV Non-small Cell Lung Cancer" ], "interventions": [ { "name": "cixutumumab", "type": "BIOLOGICAL" }, { "name": "erlotinib hydrochloride", "type": "DRUG" }, { "name": "laboratory biomarker analysis", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 18, "start_date": "2008-10", "completion_date": "2012-05", "has_results": true, "last_update_posted_date": "2014-05-21", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 2, "location_summary": "Denver, Colorado • Buffalo, New York", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00778167" }, { "nct_id": "NCT00811993", "title": "A Study of R1507 in Combination With Multiple Standard Chemotherapy Treatments in Patients With Advanced Solid Tumors", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Neoplasms" ], "interventions": [ { "name": "RG1507", "type": "DRUG" }, { "name": "RO1507", "type": "DRUG" }, { "name": "bevacizumab [Avastin]", "type": "DRUG" }, { "name": "capecitabine [Xeloda]", "type": "DRUG" }, { "name": "carboplatin", "type": "DRUG" }, { "name": "cetuximab", "type": "DRUG" }, { "name": "docetaxel", "type": "DRUG" }, { "name": "erlotinib [Tarceva]", "type": "DRUG" }, { "name": "etoposide", "type": "DRUG" }, { "name": "gemcitabine", "type": "DRUG" }, { "name": "irinotecan", "type": "DRUG" }, { "name": "mFOLFOX6", "type": "DRUG" }, { "name": "paclitaxel", "type": "DRUG" }, { "name": "pemetrexel", "type": "DRUG" }, { "name": "sorafenib", "type": "DRUG" }, { "name": "temozolomide", "type": "DRUG" }, { "name": "trastuzumab [Herceptin]", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 104, "start_date": "2009-02", "completion_date": "2012-12", "has_results": false, "last_update_posted_date": "2016-11-02", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 8, "location_summary": "Tucson, Arizona • San Francisco, California • Santa Monica, California + 5 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "San Francisco", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00811993" }, { "nct_id": "NCT01016015", "title": "Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metastatic Osteosarcoma", "Recurrent Adult Soft Tissue Sarcoma", "Recurrent Osteosarcoma", "Stage III Adult Soft Tissue Sarcoma", "Stage IV Adult Soft Tissue Sarcoma" ], "interventions": [ { "name": "Cixutumumab", "type": "BIOLOGICAL" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Temsirolimus", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "OTHER", "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 178, "start_date": "2009-11", "completion_date": "2014-07", "has_results": true, "last_update_posted_date": "2015-07-30", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 22, "location_summary": "Los Angeles, California • Jacksonville, Florida • Tampa, Florida + 16 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Tampa", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01016015" }, { "nct_id": "NCT00807612", "title": "QUILT-2.017: Phase 1b/2 Study of AMG 479 in Combination With Paclitaxel and Carboplatin for 1st Line Treatment of Advanced Squamous Non-Small Cell Lung Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Advanced Squamous Non-Small Cell Lung Cancer" ], "interventions": [ { "name": "AMG 479", "type": "BIOLOGICAL" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "NantCell, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2009-01", "completion_date": "2010-08", "has_results": true, "last_update_posted_date": "2024-09-25", "last_synced_at": "2026-05-22T04:50:57.810Z", "location_count": 25, "location_summary": "Fayetteville, Arkansas • Fort Wayne, Indiana • Indianapolis, Indiana + 9 more", "locations": [ { "city": "Fayetteville", "state": "Arkansas" }, { "city": "Fayetteville", "state": "Arkansas" }, { "city": "Fort Wayne", "state": "Indiana" }, { "city": "Fort Wayne", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00807612" } ] }