{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ichthyosis%2C+Lamellar",
    "query": {
      "condition": "Ichthyosis, Lamellar"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:47:00.599Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02864082",
      "title": "A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Congenital Ichthyosis"
      ],
      "interventions": [
        {
          "name": "PAT-001, 0.1%",
          "type": "DRUG"
        },
        {
          "name": "PAT-001, 0.2%",
          "type": "DRUG"
        },
        {
          "name": "Vehicle for PAT-001 0.1%",
          "type": "DRUG"
        },
        {
          "name": "Vehicle for PAT-001 0.2%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Patagonia Pharmaceuticals, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2017-03-08",
      "completion_date": "2018-12-04",
      "has_results": true,
      "last_update_posted_date": "2021-09-29",
      "last_synced_at": "2026-05-22T06:47:00.599Z",
      "location_count": 5,
      "location_summary": "San Diego, California • New Haven, Connecticut • Chicago, Illinois + 2 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02864082"
    },
    {
      "nct_id": "NCT03738800",
      "title": "A Safety, Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lamellar Ichthyosis"
      ],
      "interventions": [
        {
          "name": "CD5789 Cream 200 µg/g",
          "type": "DRUG"
        },
        {
          "name": "CD5789 Cream 100 µg/g",
          "type": "DRUG"
        },
        {
          "name": "CD5789 Cream Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayne Pharma International Pty Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2019-05-01",
      "completion_date": "2021-09-03",
      "has_results": true,
      "last_update_posted_date": "2023-08-14",
      "last_synced_at": "2026-05-22T06:47:00.599Z",
      "location_count": 10,
      "location_summary": "San Diego, California • Aurora, Colorado • New Haven, Connecticut + 7 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Skokie",
          "state": "Illinois"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03738800"
    },
    {
      "nct_id": "NCT00074685",
      "title": "National Registry for Ichthyosis and Related Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Darier Disease",
        "Hailey-Hailey Disease",
        "Hyperkeratosis, Epidermolytic",
        "Ichthyosis",
        "Ichthyosis, Lamellar",
        "Ichthyosis, X-Linked",
        "Keratoderma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 610,
      "start_date": "1994-09",
      "completion_date": "2004-01",
      "has_results": false,
      "last_update_posted_date": "2022-09-28",
      "last_synced_at": "2026-05-22T06:47:00.599Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00074685"
    },
    {
      "nct_id": "NCT00001292",
      "title": "Study of Scaling Disorders and Other Inherited Skin Diseases",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Genetic Skin Disease",
        "Keratosis Follicularis",
        "Lamellar Ichthyosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": null,
      "start_date": "1992-02",
      "completion_date": "2001-04",
      "has_results": false,
      "last_update_posted_date": "2008-03-05",
      "last_synced_at": "2026-05-22T06:47:00.599Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001292"
    },
    {
      "nct_id": "NCT03041038",
      "title": "The Efficacy and Safety of Secukinumab in Patients With Ichthyoses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ichthyosis",
        "Autosomal Recessive Congenital Ichthyosis",
        "Lamellar Ichthyosis",
        "Congenital Ichthyosiform Erythroderma",
        "Epidermolytic Ichthyosis",
        "Netherton Syndrome"
      ],
      "interventions": [
        {
          "name": "Secukinumab",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2016-12",
      "completion_date": "2020-08-31",
      "has_results": true,
      "last_update_posted_date": "2021-08-25",
      "last_synced_at": "2026-05-22T06:47:00.599Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • New York, New York",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03041038"
    }
  ]
}