{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immune+Dysfunction&page=46", "query": { "condition": "Immune Dysfunction", "page": 46 }, "page_size": 10 }, "pagination": { "page": 46, "page_size": 10, "total_count": 20607, "total_pages": 2061, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immune+Dysfunction&page=47&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immune+Dysfunction&page=45&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-21T16:52:58.951Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00460421", "title": "A Phase 1 Dose-escalation Study to Evaluate the Safety and Pharmacokinetics (PK) of Palifermin in Subjects With Acute Leukemias Undergoing HSCT", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Leukemia" ], "interventions": [ { "name": "Palifermin", "type": "DRUG" }, { "name": "Total Body irradiation", "type": "RADIATION" }, { "name": "Chemotherapy", "type": "DRUG" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Swedish Orphan Biovitrum", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "16 Years", "sex": "ALL", "summary": "1 Year to 16 Years" }, "enrollment_count": 27, "start_date": "2006-08", "completion_date": "2011-05", "has_results": true, "last_update_posted_date": "2014-12-05", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 7, "location_summary": "Tucson, Arizona • Loma Linda, California • Los Angeles, California + 3 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Loma Linda", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00460421" }, { "nct_id": "NCT06203106", "title": "NYSCF Scientific Discovery Biobank", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "ALS", "Amyotrophic Lateral Sclerosis", "Alzheimer Disease", "Alzheimer Disease, Early Onset", "Alzheimer Disease, Late Onset", "Batten Disease", "Corticobasal Degeneration", "Dementia", "Frontotemporal Dementia", "Huntington Disease", "Lewy Body Disease", "Multiple Sclerosis", "Multiple System Atrophy", "Parkinson Disease", "Parkinson's Disease and Parkinsonism", "Progressive Supranuclear Palsy", "INAD", "Diabetes", "Diabetes Mellitus", "Diabetes Mellitus, Type 2", "Diabetes Mellitus, Type 1", "Macular Degeneration", "Ovarian Cancer", "Cervical Cancer", "Uterine Cancer", "Vaginal Cancer", "Vulvar Cancer", "PTSD", "Post Traumatic Stress Disorder" ], "interventions": [ { "name": "Biological Sample Collection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "New York Stem Cell Foundation Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Days", "maximum_age": null, "sex": "ALL", "summary": "30 Days and older" }, "enrollment_count": 10000, "start_date": "2022-11-10", "completion_date": "2045-11-10", "has_results": false, "last_update_posted_date": "2025-03-03", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06203106" }, { "nct_id": "NCT01472406", "title": "Feasibility Study Using Zone-MPC Controller (Zone-Model Predictive Control) and Health Monitoring System (HMS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Type 1 Diabetes Mellitus" ], "interventions": [ { "name": "Sansum Closed-Loop Artificial Pancreas", "type": "DEVICE" }, { "name": "Insulin infusion pump", "type": "DEVICE" }, { "name": "Continuous Glucose Monitor", "type": "DEVICE" }, { "name": "zone-Model Predictive Control algorithm", "type": "DEVICE" }, { "name": "Safety Health Monitoring System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Sansum Diabetes Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 12, "start_date": "2011-11", "completion_date": "2014-03", "has_results": false, "last_update_posted_date": "2021-09-14", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 1, "location_summary": "Santa Barbara, California", "locations": [ { "city": "Santa Barbara", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01472406" }, { "nct_id": "NCT02355184", "title": "An Extension of Protocol PRO 140_CD01 Study", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV", "Human Immunodeficiency Virus" ], "interventions": [ { "name": "PRO 140 350mg weekly subcutaneous (SC) injection.", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "CytoDyn, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2014-11-18", "completion_date": "2022-07-15", "has_results": true, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02355184" }, { "nct_id": "NCT03387852", "title": "Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma Participants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "SAR440340", "type": "DRUG" }, { "name": "Dupilumab", "type": "DRUG" }, { "name": "Fluticasone or Fluticasone/salmeterol combination", "type": "DRUG" }, { "name": "Placebo for SAR440340", "type": "DRUG" }, { "name": "Placebo for dupilumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 296, "start_date": "2018-03-12", "completion_date": "2019-08-07", "has_results": true, "last_update_posted_date": "2022-06-14", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 18, "location_summary": "Birmingham, Alabama • Long Beach, California • Los Angeles, California + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Jose", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03387852" }, { "nct_id": "NCT02500849", "title": "Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV" ], "interventions": [ { "name": "SB-728mR-HSPC Infusion 3 days following busulfan conditioning", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 12, "start_date": "2016-03-10", "completion_date": "2027-07-23", "has_results": false, "last_update_posted_date": "2026-10-02", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 5, "location_summary": "Duarte, California • Los Angeles, California • San Francisco, California + 1 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Norwalk", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02500849" }, { "nct_id": "NCT03389347", "title": "High Throughput Drug Sensitivity and Genomics Data in Developing Individualized Treatment in Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Plasma Cell Leukemia", "Recurrent Multiple Myeloma", "Refractory Multiple Myeloma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "High Throughput Screening", "type": "DEVICE" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "OTHER" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2018-02-14", "completion_date": "2026-07-24", "has_results": true, "last_update_posted_date": "2026-09-16", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT03389347" }, { "nct_id": "NCT00491335", "title": "HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "HIV Infections", "AIDS", "Lung Cancer", "Tobacco Addiction", "Drug Addiction" ], "interventions": [], "intervention_types": [], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "17 Years", "maximum_age": null, "sex": "ALL", "summary": "17 Years and older" }, "enrollment_count": null, "start_date": "2007-06-18", "completion_date": "2010-02-16", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00491335" }, { "nct_id": "NCT00108108", "title": "Dose-finding Trial of HCD122 in Patients With Chronic Lymphocytic Leukemia (CLL) That is Relapsed or Non-responsive to Prior Fludaribine Therapy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Chronic Lymphocytic Leukemia" ], "interventions": [ { "name": "HCD122", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 26, "start_date": "2005-04", "completion_date": "2008-06", "has_results": false, "last_update_posted_date": "2012-10-01", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 5, "location_summary": "La Jolla, California • Beech Grove, Indiana • Baltimore, Maryland + 2 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Beech Grove", "state": "Indiana" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00108108" }, { "nct_id": "NCT02203825", "title": "Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Acute Myeloid Leukemia", "Myelodysplastic Syndrome", "Multiple Myeloma" ], "interventions": [ { "name": "CM-CS1 T-cell infusion", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Celyad Oncology SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 12, "start_date": "2015-03", "completion_date": "2018-03", "has_results": false, "last_update_posted_date": "2018-06-01", "last_synced_at": "2026-10-21T16:52:58.951Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02203825" } ] }